RZZ and Mad1 dynamics in Drosophila mitosis.
Paris, France. In Chromosome Res, Jun 2015
Among the factors regulating the levels of Mad1 at kinetochores is the Rod, Zw10, and Zwilch (RZZ) complex, which is required for Mad1 recruitment through a mechanism that remains unknown.
Regulators of the cytoplasmic dynein motor.
Cambridge, United States. In Nat Rev Mol Cell Biol, 2009
The answer could lie in the several multifunctional adaptors, including dynactin, lissencephaly 1, nuclear distribution protein E (NUDE) and NUDE-like, Bicaudal D, Rod-ZW10-Zwilch and Spindly, that regulate dynein function and localization.