KAP1 is a Novel Substrate for the Arginine Methyltransferase PRMT5.
Napoli, Italy. In Biology (basel), 2014
In previous papers, we analyzed the KAP1-dependent molecular mechanism of transcriptional repression mediated by ZNF224, a member of the KRAB-ZFP family, and identified the protein arginine methyltransferase PRMT5 as a component of the ZNF224 repression complex.
[Genetic profiles of longevity and healthy cognitive aging in nonagenarians from the Basque Country].
Vitoria-Gasteiz, Spain. In Rev Esp Geriatr Gerontol, 2011
In addition, 64 SNPs loci distributed in 13 candidate genes FOXO3, SIRT1, TOMM40, APOE, PICALM, COMT, CETP, CLU, CR1, IL-6, PCK-1, ZNF224 and ACE will be analysed by Taqman array.
Intermediate phenotypes identify divergent pathways to Alzheimer's disease.
Boston, United States. In Plos One, 2009
A SNP in the zinc finger protein 224 gene (ZNF224, rs3746319) was associated with both global AD neuropathology (p = 0.009) and global cognition (p = 0.002); whereas, a SNP at the phosphoenolpyruvate carboxykinase locus (PCK1, rs8192708) was selectively associated with global cognition (p = 3.57 x 10(-4)).
Identification of endogenous reference genes for qRT-PCR analysis in normal matched breast tumor tissues.
Ankara, Turkey. In Oncol Res, 2008
In this study, expression patterns of 15 widely used endogenous RGs (ACTB, TBP, GAPDH, SDHA, HPRT, HMBS, B2M, PPIA, GUSB, YWHAZ2, PGK1, RPLP0, PUM1, MRPL19, and RPL41), and three candidate genes that were selected through analysis of two independent microarray datasets (IL22RA1, TC22, ZNF224) were determined in 23 primary breast tumors and their matched normal tissues using qRT-PCR.