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Zinc finger protein 16

The protein encoded by this gene contains a C2H2 type of zinc finger, and thus may function as a transcription factor. This gene is located in a region close to ZNF7/KOX4, a gene also encoding a zinc finger protein, on chromosome 8. Two alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: zinc finger protein 1, V1a, GATA-1, ACID, lacZ
Papers on ZnF16
ZNF16 (HZF1) promotes erythropoiesis and megakaryocytopoiesis via regulation of the c-KIT gene.
Zhang et al., Beijing, China. In Biochem J, 2014
We previously characterized the zinc finger protein gene HZF1 [also known as ZNF16 (zinc finger protein 16)] and demonstrated its important roles in erythroid and megakaryocytic differentiation of K562 cells.
Zinc finger protein HZF1 promotes K562 cell proliferation by interacting with and inhibiting INCA1.
Zhang et al., Beijing, China. In Mol Med Report, 2011
Previously, we characterized a zinc finger protein gene HZF1 (ZNF16) and demonstrated that it played a significant role in the erythroid and megakaryocytic differentiation of K562 cells by knockdown of the gene.
Identification of the trans-activation domain and the nuclear location signals of human zinc finger protein HZF1 (ZNF16).
Zhang et al., Beijing, China. In Mol Biotechnol, 2010
We previously characterized a C2H2-type zinc finger protein HZF1 (ZNF16) and demonstrated its important role in erythroid and megakaryocytic differentiation.
The ancient mammalian KRAB zinc finger gene cluster on human chromosome 8q24.3 illustrates principles of C2H2 zinc finger evolution associated with unique expression profiles in human tissues.
Thiesen et al., Rostock, Germany. In Bmc Genomics, 2009
Six (ZNF7, ZNF34, ZNF250, ZNF251, ZNF252, ZNF517) of the seven locus members contain exons encoding KRAB domains, one (ZNF16) does not.
A homozygous deletion in a small cell lung cancer cell line involving a 3p21 region with a marked instability in yeast artificial chromosomes.
van de Ven et al., Groningen, Netherlands. In Cancer Res, 1994
The homozygous deletion maps between UBE1L and ZnF16, just centromeric to D3F15S2.
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