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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Zinc finger homeobox 4

zfh-4, ZFHX4, zinc finger homeodomain 4
Top mentioned proteins: HAD, ACID, ATBF1, zfh-2, CAN
Papers on zfh-4
Identification of Drosophila Zfh2 as a Mediator of Hypercapnic Immune Regulation by a Genome-Wide RNA Interference Screen.
Beitel et al., Evanston, United States. In J Immunol, Feb 2016
In vivo tests of one of the strongest screen hits, zinc finger homeodomain 2 (Zfh2; mammalian orthologs ZFHX3/ATBF1 and ZFHX4), demonstrate that reducing zfh2 function using a mutation or RNA interference improves survival of flies exposed to elevated CO2 and infected with Staphylococcus aureus.
New basal cell carcinoma susceptibility loci.
Stefansson et al., Reykjavík, Iceland. In Nat Commun, 2014
P=1.5 × 10(-9)), 8q21 ZFHX4 (rs28727938[G], OR=0.70,
ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state.
Chheda et al., Cambridge, United States. In Cell Rep, 2014
To understand the regulation of the TIC state, we performed an image-based screen for genes regulating GBM TIC maintenance and identified ZFHX4, a 397 kDa transcription factor.
Identification of novel candidate gene loci and increased sex chromosome aneuploidy among infants with conotruncal heart defects.
Lammer et al., Oakland, United States. In Am J Med Genet A, 2014
From these duplications and deletions, we found five high priority candidate genes (GATA4, CRKL, BMPR1A, SNAI2, and ZFHX4).
Clinical significance of de novo and inherited copy-number variation.
de Vries et al., Nijmegen, Netherlands. In Hum Mutat, 2013
In addition, we identified 20 de novo single-gene CNVs that directly indicate novel genes for ID/MCA, including ZFHX4, ANKH, DLG2, MPP7, CEP89, TRIO, ASTN2, and PIK3C3.
Characterization of a 8q21.11 microdeletion syndrome associated with intellectual disability and a recognizable phenotype.
Lapunzina et al., Madrid, Spain. In Am J Hum Genet, 2011
The smallest region of overlap was a 539.7 kb interval encompassing three genes: a Zinc Finger Homeobox 4 (ZFHX4), one microRNA of unknown function, and one nonfunctional pseudogen.
A single nucleotide polymorphism-derived regulatory gene network underlying puberty in 2 tropical breeds of beef cattle.
Hawken et al., Australia. In J Anim Sci, 2011
As a novel finding, we report 5 TF (HIVEP3, TOX, EYA1, NCOA2, and ZFHX4) located in the network intersecting both breeds and interacting with other TF, forming a regulatory network that harmonizes with the recent literature of puberty.
Genome-wide scan of 500,000 single-nucleotide polymorphisms among responders and nonresponders to interferon beta therapy in multiple sclerosis.
Montalban et al., Barcelona, Spain. In Arch Neurol, 2009
Of these, 7 SNPs were located in genes that code for alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid-type glutamate receptor GRIA3, type 1 interferon-related proteins ADAR and IFNAR2, cell cycle-dependent protein CIT, zinc finger proteins ZFAT and ZFHX4, and guanosine triphosphatase-activating protein STARD13.
Genome-wide linkage analysis and mutation analysis of hereditary congenital blepharoptosis in a Japanese family.
Yoshiura et al., Nagasaki, Japan. In J Hum Genet, 2007
In addition, in a sporadic case with a balanced chromosomal translocation t(1;8) (p34.3;q21.12), the ZFHX4 (zinc finger homeodomain 4) gene was found to be disrupted at the 8q21.12
A homeodomain-zinc finger protein, ZFHX4, is expressed in neuronal differentiation manner and suppressed in muscle differentiation manner.
Tsuchiya et al., Machida, Japan. In Biol Pharm Bull, 2006
Human ZFHX4 has recently been shown to be a candidate gene for congenital bilateral isolated ptosis.
Microarray analysis reveals differential gene expression patterns in tumors of the pineal region.
Lachuer et al., Lyon, France. In J Neuropathol Exp Neurol, 2006
PTPRs, classified with chordoid glioma and separately from ependymomas, showed high expression of SPEDF, KRT18, and genes encoding proteins reported to be expressed in the subcommissural organ, namely ZFH4, RFX3, TTR, and CGRP.
ZFH4 protein is expressed in many neurons of developing rat brain.
Sasahara et al., Toyama, Japan. In J Comp Neurol, 2005
We have cloned the ZFH4 gene that encodes a protein with structures closely related to ATBF1.
A candidate gene for congenital bilateral isolated ptosis identified by molecular analysis of a de novo balanced translocation.
Robinson et al., Southampton, United Kingdom. In Hum Genet, 2002
Human ZFH-4 is a candidate gene for congenital bilateral isolated ptosis, identified by molecular analysis of a de novo balanced translocation.
The mouse ZFH-4 protein contains four homeodomains and twenty-two zinc fingers.
Tamaoki et al., Machida, Japan. In Biochem Biophys Res Commun, 2000
We isolated the mouse zfh-4 cDNA which is 12 kb long and capable of encoding a 3,550-amino acid protein containing four homeodomains and 22 zinc fingers including two pseudo zinc finger motifs.
Expression of zfh-4, a new member of the zinc finger-homeodomain family, in developing brain and muscle.
Sanes et al., Saint Louis, United States. In Dev Dyn, 1995
We have identified zfh-4, a new member of a recently recognized zinc finger-homeodomain (zfh) family of putative transcription factors.
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