Unorthodox methods for enhancing solvent production in solventogenic Clostridium species.
Wooster, United States. In Appl Microbiol Biotechnol, Feb 2016
In this review, the impacts of metabolic perturbations including medium supplementation with glycerol; furfural and 5-hydroxymethyl furfural; allopurinol, an inhibitor of xanthine dehydrogenase; calcium (Ca(2+)) and zinc (Zn(2+)) ions); and artificial electron carriers, methyl viologen and neutral red, on butanol production are discussed.
Molybdenum cofactor deficiency.
Houston, United States. In Mol Genet Metab, Jan 2016
MoCD results in deficiency of the molybdenum cofactor dependent enzymes sulfite oxidase, xanthine dehydrogenase, aldehyde oxidase and mitochondrial amidoxime reducing component.
Oxidative stress and myocarditis.
Tokyo, Japan. In Curr Pharm Des, Dec 2015
ROS are produced by mitochondrial respiratory chain reactions and enzymes including NADPH oxidases, cyclooxygenase, and xanthine oxidase.
Reperfusion injury and reactive oxygen species: The evolution of a concept.
Shreveport, United States. In Redox Biol, Dec 2015
Of the potential ROS sources described to date, xanthine oxidase, NADPH oxidase (Nox), mitochondria, and uncoupled nitric oxide synthase have gained a status as the most likely contributors to reperfusion-induced oxidative stress and represent priority targets for therapeutic intervention against reperfusion-induced organ dysfunction and tissue damage.
Gout therapeutics: new drugs for an old disease.
United States. In Lancet, 2011
The approval of febuxostat, a non-purine-analogue inhibitor of xanthine oxidase, by the European Medicines Agency and the US Food and Drug Administration heralds a new era in the treatment of gout.