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1: Title: ZNF830 mediates cancer chemoresistance through promoting homologous-recombination repair.
Authors: Chen, Guo, .
Journal: Nucleic acids research (Nucleic Acids Res), 2017 .
Snippet: ZNF830 directly and preferentially binds to double-strand DNA with its 3' or 5' overhang through the Zinc finger (Znf) domain, facilitating HR repair and maintaining genome stability.
Affiliation: The First Affiliated Hospital, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health and Key Laboratory of Organ Transplantation of Zhejiang Province, School of Medicine, Zhejiang University, Hangzhou 310003, PR China. Department of Radiation Oncology, Emory University School of Medicine and Winship Cancer Institute of Emory University, Atlanta, GA 30322, USA. Holistic Integrative Pharmacy Institutes (HIPI), Hangzhou Normal University, Key Laboratory of Elemene Class Anti-cancer Chinese Medicine of Zhejiang Province, Engineering Laboratory of Development and Application of Traditional Chinese Medicine from Zhejiang Province, Hangzhou 311100, PR China. Laboratory of Cancer Genomics, Division of Cellular and Molecular Research, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore 169610, Singapore. Engineering Research Center of Molecular and Neuro Imaging, Ministry of Education, School of Life Science and Technology, Xidian University, Xi'an 710071, China. Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi 710032, China. Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, USA. .
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2: Title: Genetic Variants in CD44 and MAT1A Confer Susceptibility to Acute Skin Reaction in Breast Cancer Patients Undergoing Radiation Therapy.
Journal: International journal of radiation oncology, biology, physics (Int J Radiat Oncol Biol Phys), Vol. 97 (1): 118-127, 2017 .
Snippet: We tested 22 genetic variants reported in 18 genes (ie, NFE2L2, OGG1, NEIL3, RAD17, PTTG1, REV3L, ALAD, CD44, RAD9A, TGFβR3, MAD2L2, MAP3K7, MAT1A, RPS6KB2, ZNF830, SH3GL1, BAX, and XRCC1) using TaqMan assay-based real-time polymerase chain reaction.
Affiliation: Department of Radiation Biology and Toxicology, School of Life Sciences, Manipal University, Manipal, Karnataka, India. Department of Biotechnology, School of Life Sciences, Manipal University, Manipal, Karnataka, India. Department of Radiotherapy and Oncology, Shirdi Saibaba Cancer Hospital and Research Centre, Kasturba Hospital, Manipal, Karnataka, India. Department of Radiation Oncology, Manipal Hospital, Bengaluru, Karnataka, India. Advanced Radiation Biology Research Program, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba, Japan. Department of Biotechnology, School of Life Sciences, Manipal University, Manipal, Karnataka, India. Electronic address: .
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