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13 documents found
1: Title: Investigating core genetic-and-epigenetic cell cycle networks for stemness and carcinogenic mechanisms, and cancer drug design using big database mining and genome-wide next-generation sequencing data.
Authors: Li, Cheng-Wei, .
Journal: Cell cycle (Georgetown, Tex.) (Cell Cycle), Vol. 15 (19): 2593-2607, 2016 .
Snippet: We found that dysregulation of miR-29C, miR-34A, miR-98, and miR-215; and methylation of ANKRD1, ARID5B, CDCA2, PIF1, STAMBPL1, TROAP, ZNF165, and HIST1H2AJ in HeLa cells could result in cell proliferation and anti-apoptosis through NFκB, TGF-β, and PI3K pathways.
Affiliation: a Department of Electrical Engineering , National Tsing Hua University , Hsinchu , Taiwan. .
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2: Title: Comprehensive functional characterization of cancer-testis antigens defines obligate participation in multiple hallmarks of cancer.
Authors: Maxfield, Kimberly E, .
Journal: Nature communications (Nat Commun), Vol. 6, 2015 .
Snippet: Furthermore, ZNF165 promotes TGFβ signalling by directly suppressing the expression of negative feedback regulatory pathways.
Affiliation: Simmons Comprehensive Cancer Center, UT-Southwestern Medical Center, Dallas, Texas 75390, USA. Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA. Department of Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA. Department of Clinical Science, UT-Southwestern Medical Center, Dallas, Texas 75390, USA. Department of Neuroscience, UT-Southwestern Medical Center, Dallas, Texas 75390, USA. Eugene McDermott Center for Human Growth and Development, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA. .
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3: Title: Frequent expression of zinc-finger protein ZNF165 in human urinary bladder transitional cell carcinoma.
Authors: Singh, Pankaj Kumar, .
Journal: Immunobiology, Vol. 220 (1): 68-73, 2015 .
Snippet: Our study results suggest that ZNF165 mRNA/protein expression was observed in TCC of human urinary bladder and might be used as a novel diagnostic biomarker and as well a vaccine target in development of urinary bladder cancer specific immunotherapy.
Affiliation: Department of Radiotherapy, King George's Medical University, Lucknow, Uttar Pradesh 226003, India. Department of Urology, King George's Medical University, Lucknow, Uttar Pradesh 226003, India. Genotoxicity Laboratory, Division of Toxicology, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh 226031, India. Department of Pathology, King George's Medical University, Lucknow, Uttar Pradesh 226003, India. Department of Radiation Oncology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh 226010, India. Electronic address: .
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4: Title: Deletion variant near ZNF389 is associated with control of ovine lentivirus in multiple sheep flocks.
Authors: White, S N, .
Journal: Animal genetics (Anim Genet), Vol. 45 (2): 297-300, 2014 .
Snippet: Ovine lentivirus (OvLV) is a macrophage-tropic lentivirus found in many countries that causes interstitial pneumonia, mastitis, arthritis and cachexia in sheep.
Affiliation: Animal Disease Research Unit, Agricultural Research Service, U.S. Department of Agriculture, Pullman, WA, 99164, USA; Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, 99164, USA. .
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5: Title: Genome-wide association identifies multiple genomic regions associated with susceptibility to and control of ovine lentivirus.
Authors: White, Stephen N, .
Journal: PloS one, Vol. 7 (10): e47829, 2012 .
Snippet: Genes in regions associated with control of infection included a zinc finger cluster (ZNF192, ZSCAN16, ZNF389, and ZNF165; P=0.001), C19orf42/TMEM38A (P=0.047), and DLGAP1 (P=0.092).
Affiliation: Animal Disease Research Unit, Agricultural Research Service, U. S. Department of Agriculture, Pullman, Washington, USA. .
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6: Title: A new 500 kb haplotype associated with high CD8+ T-lymphocyte numbers predicts a less severe expression of hereditary hemochromatosis.
Authors: Cruz, Eugénia, .
Journal: BMC medical genetics (Bmc Med Genet), Vol. 9, 2008 .
Snippet: In a small proportion of patients, another conserved haplotype defined by the SNP markers PGBD1-G, ZNF193-G, ZNF165-G (designated as G-G-G) was found associated with high CD8+ T-lymphocyte numbers and a milder clinical expression.
Affiliation: Clinical Hematology, Santo António Hospital, Porto, Portugal. .
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7: Title: Expression of cancer-testis antigens as possible targets for antigen-specific immunotherapy in head and neck squamous cell carcinoma.
Authors: Atanackovic, Djordje, .
Journal: Cancer biology & therapy (Cancer Biol Ther), Vol. 5 (9): 1218-25, 2006 .
Snippet: ADAM2, LIP1, SLLP1, AKAP3, CTAGE, ZNF165, CAGE, and FTHL17 were expressed in tumor and healthy tissue at comparable frequencies.
Affiliation: Department of Oncology/Hematology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. .
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8: Title: Zinc-finger protein ZNF165 is a novel cancer-testis antigen capable of eliciting antibody response in hepatocellular carcinoma patients.
Authors: Dong, X-Y, .
Journal: British journal of cancer (Brit J Cancer), Vol. 91 (8): 1566-70, 2004 .
Snippet: RT-PCR, real-time PCR and Northern blotting analysis confirmed that ZNF165 mRNA was expressed in the hepatocellular carcinoma, gastric cancer, colon cancer and non-small-cell lung carcinoma.
Affiliation: Department of Immunology, School of Basic Medical Science, Peking University Health Science Center, 38 Xue Yuan Road, Beijing 100083, China. .
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9: Title: [Development of a K562 multidrug-resistant cell line and study on proteins with altered expression].
Authors: Wang, Yi, .
Journal: Shi yan sheng wu xue bao, Vol. 36 (5): 342-6, 2003 .
Snippet: In an attempt to study the whole protein expression alterations of tumer cells after becoming multidrug-resistant, which may provide useful information on new drug target identification, an adriamycin-resistant variant of the human leukemia cell line K562 (K562/ADR) was developed in vitro by continuous exposure to adrimycin.
Affiliation: Cancer Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China. .
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10: Title: Familial t(6;21)(p21.1;p13) translocation associated with male-only sterility.
Authors: Paoloni-Giacobino, A, .
Journal: Clinical genetics (Clin Genet), Vol. 58 (4): 324-8, 2000 .
Snippet: Southern blot analysis showed that the gene ZNF165, which maps to this region and which is specifically expressed in the testis, was not disrupted by the translocation.
Affiliation: Division of Medical Genetics, Geneva University Hospital, Switzerland. .
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11: Title: The zinc finger-associated SCAN box is a conserved oligomerization domain.
Authors: Williams, A J, .
Journal: Molecular and cellular biology (Mol Cell Biol), Vol. 19 (12): 8526-35, 1999 .
Snippet: A number of Cys(2)His(2) zinc finger proteins contain a highly conserved amino-terminal motif termed the SCAN domain.
Affiliation: Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA. .
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12: Title: Three genes encoding zinc finger proteins on human chromosome 6p21.3: members of a new subclass of the Kruppel gene family containing the conserved SCAN box domain.
Authors: Lee, P L, .
Journal: Genomics, Vol. 43 (2): 191-201, 1997 .
Snippet: The complete cDNA sequence, genomic structure, and tissue distribution of three of the zinc finger proteins, LD65/ZNF165, ZNF192 (previously called LD5-1), and ZNF193, are described.
Affiliation: Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California 92037, USA. .
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13: Title: Characterization of a novel zinc finger gene (ZNF165) mapping to 6p21 that is expressed specifically in testis.
Authors: Tirosvoutis, K N, .
Journal: Genomics, Vol. 28 (3): 485-90, 1995 .
Snippet: Analysis of somatic cell hybrids containing single human chromosomes shows that ZNF165 maps to chromosome 6.
Affiliation: University of Cambridge, Department of Pathology, United Kingdom. .
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