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8 documents found
1: Title: Up-regulation of YPEL1 and YPEL5 and down-regulation of ITGA2 in erlotinib-treated EGFR-mutant non-small cell lung cancer: A bioinformatic analysis.
Authors: Wu, Xiaoli .
Journal: Gene, Vol. 643, 2018 .
Snippet: CONCLUSION: YPEL1 and YPEL5 may be related to the action of erlotinib, and down-regulation of ITGA2 may be associated with the development of acquired resistance to erlotinib in EGFR-mutant NSCLCs.
Affiliation: Department of pharmacy, Huai'an First People's Hospital, Nanjing Medical University, No. 1 West Huanghe Road, Huaiyin District, Huai'an, Jiangsu 223300, China. Electronic address: hayyky@163.com. .
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2: Title: Pro-Apoptotic Role of the Human YPEL5 Gene Identified by Functional Complementation of a Yeast moh1Δ Mutation.
Authors: Lee, Ji Young, et.al. .
Journal: Journal of microbiology and biotechnology (J Microbiol Biotechnol), Vol. 27 (3): 633-643, 2017 .
Snippet: To examine the pro-apoptotic role of the human ortholog (YPEL5) of the Drosophila Yippee protein, the cell viability of Saccharomyces cerevisiae mutant strain with deleted MOH1, the yeast ortholog, was compared with that of the wild-type (WT)-MOH1 strain after exposure to different apoptogenic stimulants, including UV irradiation, methyl methanesulfonate (MMS), camptothecin (CPT), heat shock, and hyperosmotic shock.
Affiliation: Laboratory of Immunobiology, School of Life Science and Biotechnology, College of Natural Sciences, Kyungpook National University, Daegu 41566, Republic of Korea. Department of Biological Sciences, Andong National University, Andong 36729, Republic of Korea. .
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3: Title: Association of a Network of Interferon-Stimulated Genes with a Locus Encoding a Negative Regulator of Non-conventional IKK Kinases and IFNB1.
Authors: Jeidane, Saloua, et.al. .
Journal: Cell reports (Cell Rep), Vol. 17 (2): 425-435, 2016 .
Snippet: In human HEK293T cells, YPEL5 silencing enhanced the induction of IFNB1 by pattern recognition receptors and phosphorylation of TBK1/IKBKE kinases, whereas co-immunoprecipitation experiments revealed that YPEL5 interacted physically with IKBKE.
Affiliation: Cardiovascular Biology Research Unit, Institut de Recherches Cliniques de Montréal (IRCM), Montréal, QC H2W 1R7, Canada; Département de Médecine, Faculté de Médecine, Université de Montréal, Montréal, QC J2S 2M2, Canada. Département de Médecine, Faculté de Médecine, Université de Montréal, Montréal, QC J2S 2M2, Canada; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CR-CHUM), Montréal, QC H2X 3J4, Canada. Cardiovascular Biology Research Unit, Institut de Recherches Cliniques de Montréal (IRCM), Montréal, QC H2W 1R7, Canada. Cardiovascular Biology Research Unit, Institut de Recherches Cliniques de Montréal (IRCM), Montréal, QC H2W 1R7, Canada; Département de Médecine, Faculté de Médecine, Université de Montréal, Montréal, QC J2S 2M2, Canada. Electronic address: deschec@ircm.qc.ca. .
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4: Title: The YPEL5-PPP1CB fusion transcript is detected in different hematological malignancies and in normal samples.
Authors: Vandepoele, Karl, et.al. .
Journal: Leukemia research reports (Unknown Journal), Vol. 4 (2): 51-4, 2015 .
Snippet: Here we show that the YPEL5-PPP1CB fusion is not specific for CLL but is also detected in other hematological malignancies such as chronic myeloid leukemia, monoclonal B cell lymphocytosis or acute leukemia and also in normal samples.
Affiliation: Laboratory for Molecular Diagnostics-Hematology, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium. Department of Clinical Chemistry, Microbiology and Immunology, Ghent University, De Pintelaan 185, 9000 Ghent, Belgium. .
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5: Title: Recurrent reciprocal RNA chimera involving YPEL5 and PPP1CB in chronic lymphocytic leukemia.
Journal: Proceedings of the National Academy of Sciences of the United States of America (Proc Natl Acad Sci U S A), Vol. 110 (8): 3035-40, 2013 .
Snippet: Using paired-end transcriptome sequencing, we identified recurrent and reciprocal RNA chimeras involving yippee like 5 (YPEL5) and serine/threonine-protein phosphatase PP1-beta-catalytic subunit (PPP1CB) in CLL.
Affiliation: Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA. .
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6: Title: HOXC4 homeoprotein efficiently expands human hematopoietic stem cells and triggers similar molecular alterations as HOXB4.
Authors: Auvray, Céline, et.al. .
Journal: Haematologica, Vol. 97 (2): 168-78, 2012 .
Snippet: Certain molecules identified herein are factors reported to be involved in stem cell fate or expansion in other models, such as MEF2C, EZH2, DBF4, DHX9, YPEL5 and Pumilio.
Affiliation: Inserm U1016, Institut Cochin, Paris. .
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7: Title: YPEL5 protein of the YPEL gene family is involved in the cell cycle progression by interacting with two distinct proteins RanBPM and RanBP10.
Authors: Hosono, Katsuhiro, et.al. .
Journal: Genomics, Vol. 96 (2): 102-11, 2010 .
Snippet: During cell cycle, YPEL5 protein was detected at different subcellular localizations; at interphase, it was located in the nucleus and centrosome, then it changed location sequentially to spindle poles, mitotic spindle, and spindle midzone during mitosis, and finally transferred to midbody at cytokinesis.
Affiliation: Department of Medical Photobiology, Photon Medical Research Center, Hamamatsu University School of Medicine, Higashi-ku, Japan. mino@hama-med.ac.jp .
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8: Title: Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species.
Authors: Hosono, Katsuhiro, et.al. .
Journal: Gene, Vol. 340 (1): 31-43, 2004 .
Snippet: YPEL5 protein is localized to the centrosome and nucleus during interphase and at the mitotic spindle during mitosis of the same cell line.
Affiliation: Department of Molecular Biology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan. .
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