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1: Title: An epigenome-wide study of cord blood DNA methylations in relation to prenatal perfluoroalkyl substance exposure: The Hokkaido study.
Authors: Miura, Ryu, et.al. .
Journal: Environment international (Environ Int), Vol. 115, 2018 .
Snippet: Among the top 20 DMPs ranked by the lowest P-values for perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) exposure, four DMPs showed the same direction of effect and P-value < 0.05 in the replication assay: cg16242615 mapped to ZBTB7A, cg21876869 located in the intergenic region (IGR) of USP2-AS1, cg00173435 mapped to TCP11L2, and cg18901140 located in IGR of NTN1.
Affiliation: Hokkaido University Center for Environmental and Health Sciences, Sapporo, Japan. National Institute of Environmental Health Sciences, National Health Research Institutes, Zhunan, Taiwan. National Institute of Cancer Research, National Health Research Institutes, Zhunan, Taiwan; Taiwan Bioinformatics Core, National Health Research Institutes, Zhunan, Taiwan. Department of Health Sciences, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Japan. Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan. Department of Physiology and Molecular Sciences, Hoshi University, Tokyo, Japan. Department of Biostatistics, Graduate School of Medicine, Hokkaido University, Sapporo, Japan. Faculty of Child Studies, Seitoku University, Chiba, Japan. Hokkaido University Center for Environmental and Health Sciences, Sapporo, Japan. Electronic address: rkishi@med.hokudai.ac.jp. .
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