refine search
Authors
Locations
Journals
Publication Dates
Find concepts in Knowledge Base
Explore current query
documentsstatisticstop authorclipboard
12 documents found
1: Title: Identification of differentiated functional modules in papillary thyroid carcinoma by analyzing differential networks.
Authors: Yang, Chunxiao, et.al. .
Journal: Journal of cancer research and therapeutics (J Cancer Res Ther), Vol. 14 (Supplement): S969-S974, 2018 .
Snippet: Significant changes in the expression levels between PTC and normal tissues suggest that SCOC, SYPL1, or THAP1 may play a vital role in the incidence and development of PTC, which serve as potential biomarkers for the diagnosis of PTC.
Affiliation: Department of General Surgery, Linzi District People's Hospital, Zibo 255 400, Shandong Province, China. Department of Ultrasound, Linzi District People's Hospital, Zibo 255 400, Shandong Province, China. .
Related Products: order online
2: Title: Molecular partners of hNOT/ALG3, the human counterpart of the Drosophila NOT and yeast ALG3 gene, suggest its involvement in distinct cellular processes relevant to congenital disorders of glycosylation, cancer, neurodegeneration and a variety of further pathologies.
Authors: Hacker, Benedikt, et.al. .
Journal: Human molecular genetics (Hum Mol Genet), 2018 .
Snippet: We disclose the building of hNOT/ALG3 homodimers and provide experimental evidence for its in vivo interaction with the functionally linked proteins OSBP, OSBPL9 and LRP1, the SYPL1 protein and the transcription factor CREB3. Regarding the latter, we show that the 55 kDa N-glycosylated hNOT-1/ALG3-1 molecule binds the N-glycosylated CREB3 precursor but does not interact with CREB3's proteolytic products specific to the endoplasmic reticulum and to the nucleus.
Affiliation: Institute of Medical Microbiology and Hygiene, Laboratory for Comparative Tumour Biology, University Medical Centre,Johannes Gutenberg University, Obere Zahlbacher Str. 63, 55131 Mainz, Germany. .
Related Products: order online
3: Title: SYPL1 overexpression predicts poor prognosis of hepatocellular carcinoma and associates with epithelial-mesenchymal transition.
Authors: Chen, Dong-Han, et.al. .
Journal: Oncology reports (Oncol Rep), Vol. 38 (3): 1533-1542, 2017 .
Snippet: Herein, we performed integrative experiments of quantitative real-time polymerase chain reaction (qRT-PCR), western blot analysis and immunohistochemistry (IHC), and found that SYPL1 overexpression in HCC tissues was closely correlated with several malignant clinicopathologic features of HCC.
Affiliation: Department of General Surgery, Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China. Biobank, The First Affiliated Hospital of Xiamen University, Teaching Hospital of Fujian Medical University, Xiamen, Fujian 361003, P.R. China. Department of Hepato-Biliary-Pancreatic and Vascular Surgery, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian 361003, P.R. China. .
Related Products: order online
4: Title: Evolutionary history and adaptive significance of the polymorphic Pan I in migratory and stationary populations of Atlantic cod (Gadus morhua).
Authors: Andersen, Øivind, et.al. .
Journal: Marine genomics (Mar Genomics), Vol. 22, 2015 .
Snippet: We searched for SYP family genes in phylogenetic key species and identified a single syp-related gene in three invertebrate chordates, while four members, Syp, Sypl1, Sypl2 and synaptoporin (Synpr), were found in tetrapods, Comoran coelacanth and spotted gar.
Affiliation: Nofima, P.O. Box 5010, N-1430 Ås, Norway; Department of Animal and Aquaculture Sciences, University of Life Sciences, P.O. Box 5003, N-1430 Ås, Norway. Electronic address: oivind.andersen@nofima.no. Nofima, Muninbakken 9-13, N-9291 Tromsø, Norway. Electronic address: hanne.johnsen@nofima.no. Institute of Chemistry of Molecular Recognition-CNR and Institute of Biochemistry and Clinical Biochemistry, Catholic University of Rome, 00168 Rome, Italy. Electronic address: mariacristina.derosa@icrm.cnr.it. Department of Arctic and Marine Biology, UiT The Arctic University of Norway, N-9037 Tromsø, Norway. Electronic address: kim.praebel@uit.no. Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Box 7023, S-75007 Uppsala, Sweden. Electronic address: suzana.stjelja@gmail.com. Department of Animal and Aquaculture Sciences, University of Life Sciences, P.O. Box 5003, N-1430 Ås, Norway. Electronic address: tina.graceline@nmbu.no. Institute of Biochemistry and Clinical Biochemistry, Catholic University of Rome, 00168 Rome, Italy. Electronic address: davide.pirolli@rm.unicatt.it. Centre for Ecological and Evolutionary Synthesis (CEES), Department of Biosciences, University of Oslo, P.O. Box 1066 Blindern, N-0316 Oslo, Norway. Electronic address: sissel.jentoft@ibv.uio.no. Department of Arctic and Marine Biology, UiT The Arctic University of Norway, N-9037 Tromsø, Norway. Electronic address: svein-erik.fevolden@uit.no. .
Related Products: order online
5: Title: Exome sequencing followed by genotyping suggests SYPL2 as a susceptibility gene for morbid obesity.
Authors: Jiao, Hong, et.al. .
Journal: European journal of human genetics : EJHG (Eur J Hum Genet), Vol. 23 (9): 1216-22, 2015 .
Snippet: rs62623713 is a low-frequency (2.9% minor allele frequency) non-synonymous variant (E99G) in exon 4 of the synaptophysin-like 2 (SYPL2) gene.
Affiliation: Department of Biosciences and Nutrition, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden. Department of Medicine (H7), Karolinska Institutet, Stockholm, Sweden. 1] Department of Orthopaedics, Karolinska University Hospital, Stockholm, Sweden [2] CLINTEC, Karolinska Institutet, Stockholm, Sweden. Cardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden. Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden. 1] Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden [2] Department of Surgery, Ersta Hospital, Karolinska Institutet, Stockholm, Sweden. .
Related Products: order online
6: Title: The JNK1/JNK3 interactome--contributions by the JNK3 unique N-terminus and JNK common docking site residues.
Authors: Chen, Wei-Kai, et.al. .
Journal: Biochemical and biophysical research communications (Biochem Biophys Res Commun), Vol. 453 (3): 576-81, 2014 .
Snippet: ΔN JNK3α1), and interaction evaluation in the yeast two-hybrid system defined the interacting partners as either JNK1-specific interactors (ATF7, FUS, KCNE4, PIAS1, SHANK1, TKT), typical JBD-dependent interactors shared by JNK1α1 and JNK3α1 (AKAP6, BMPR2, EEF1A1, GFAP, GRIP2, GTF2F1, HDAC2, MAP1B, MYO9B, PTPN2, RABGAP1, RUSC2, SUMO1, SYPL1, TOPBP1, ZNF668), or JNK3-specific partners (ATXN1, NNAT, PTGDS) dependent on interaction with the JNK3 N-terminal extension.
Affiliation: Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Victoria 3010, Australia. Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Victoria 3010, Australia. Electronic address: marieb@unimelb.edu.au. .
Related Products: order online
7: Title: Elevated synaptophysin I in the prefrontal cortex of human chronic alcoholics.
Authors: Henriksson, Richard, et.al. .
Journal: Synapse (New York, N.Y.) (Synapse), Vol. 62 (11): 829-33, 2008 .
Snippet: To address this hypothesis in the context of ethanol dependence in humans, we used semiquantitative immunoblotting to compare the immunoreactivities of synaptophysin I, syntaxin 1A, synaptosome-associated protein 25, and vesicle-associated membrane protein in the prefrontal and motor cortices between chronic alcoholics and control subjects.
Affiliation: Experimental Alcohol and Drug Dependence Research, Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden. richard.henriksson@ki.se .
Related Products: order online
8: Title: The influence of phylogenetic uncertainty on the detection of positive Darwinian selection.
Journal: Molecular biology and evolution (Mol Biol Evol), Vol. 23 (12): 2274-8, 2006 .
Snippet: Although the influence of transition:transversion and codon biases have been investigated in detail, little is known about how inaccuracy in the phylogeny used during the calculations affects the performance of these tests.
Affiliation: Departamento de Zoologia, Universidade Federal do Paraná, Curitiba, PR, Brazil. pie@ufpr.br .
Related Products: order online
9: Title: The adipocyte as a secretory organ: mechanisms of vesicle transport and secretory pathways.
Authors: Bradley, R L, et.al. .
Journal: Recent progress in hormone research (Recent Prog Horm Res), Vol. 56, 2001 .
Snippet: This includes regulation of leptin synthesis and secretion by insulin and glucocorticoids and, more recently, the finding that the orexigenic neuropeptide, melanin-concentrating hormone (MCH), can stimulate leptin synthesis and secretion.
Affiliation: Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts 02215, USA. .
Related Products: order online
10: Title: Nucleotide polymorphism and natural selection at the pantophysin (Pan I) locus in the Atlantic cod, Gadus morhua (L.).
Journal: Genetics, Vol. 157 (1): 317-30, 2001 .
Snippet: The present study tested the role of spatially varying selection in producing significant linkage disequilibrium and large differences in the frequencies of two common alleles at the pantophysin (Pan I) locus among five populations of the Atlantic cod, Gadus morhua.
Affiliation: Department of Ecology and Evolutionary Biology, University of California, Santa Cruz, California 95064, USA. pogson@darwin.ucsc.edu .
Related Products: order online
11: Title: Pantophysin is a phosphoprotein component of adipocyte transport vesicles and associates with GLUT4-containing vesicles.
Authors: Brooks, C C, et.al. .
Journal: The Journal of biological chemistry (J Biol Chem), Vol. 275 (3): 2029-36, 2000 .
Snippet: In the present study, Northern blots showed that pantophysin mRNA was abundant in adipose tissue and increased during adipogenesis of 3T3-L1 cells.
Affiliation: Research Division, Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts 02215, USA. .
Related Products: order online
12: Title: Pantophysin is a ubiquitously expressed synaptophysin homologue and defines constitutive transport vesicles.
Authors: Haass, N K, et.al. .
Journal: The Journal of cell biology (J Cell Biol), Vol. 134 (3): 731-46, 1996 .
Snippet: Using antibodies against the unique carboxy terminus pantophysin can be detected by immunofluorescence microscopy in both exocrine and endocrine cells of human pancreas, and in cultured cells, colocalizing with constitutive secretory and endocytotic vesicle markers in nonneuroendocrine cells and with synaptophysin in cDNA-transfected epithelial cells.
Affiliation: Division of Cell Biology, German Cancer Research Center, Heidelberg, Federal Republic of Germany. .
Related Products: order online
Documents per page: 20 | 50 | 100