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10 documents found
1: Title: Decreased expression of the mitochondrial solute carrier SLC25A43 in basal cell carcinoma compared with healthy skin.
Authors: Prosén, Sara, et.al. .
Journal: Oncology letters (Oncol Lett), Vol. 14 (2): 2218-2222, 2017 .
Snippet: The aim of the present study was to investigate the gene and protein expression of the mitochondrial solute carrier family 25 member 43 (SLC25A43) in basal cell carcinoma.
Affiliation: Department of Dermatology, Örebro University Hospital, SE-701 85 Örebro, Sweden. Department of Clinical Research Laboratory, Faculty of Medicine and Health, Örebro University, SE-701 82 Örebro, Sweden. School of Medical Sciences, Faculty of Medicine and Health, Örebro University, SE-701 82 Örebro, Sweden. .
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2: Title: De novo assembly of the ringed seal (Pusa hispida) blubber transcriptome: A tool that enables identification of molecular health indicators associated with PCB exposure.
Authors: Brown, Tanya M, et.al. .
Journal: Aquatic toxicology (Amsterdam, Netherlands) (Aquat Toxicol), Vol. 185, 2017 .
Snippet: We found an indication of energy metabolism imbalance in local ringed seals (n=4), and identified five significant gene transcript targets: plasminogen receptor (Plg-R(KT)), solute carrier family 25 member 43 receptor (Slc25a43), ankyrin repeat domain-containing protein 26-like receptor (Ankrd26), HIS30 (not yet annotated) and HIS16 (not yet annotated) that may represent indicators of PCB exposure and effects in marine mammals.
Affiliation: Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia V8W 3P6, Canada; Memorial University, St. John's, Newfoundland A1B 3X9, Canada. Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia V8W 3P6, Canada; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC V5Z 4S6, Canada. Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC V5Z 4S6, Canada. Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia V8W 3P6, Canada. Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia V8W 3P6, Canada. Electronic address: chelbing@uvic.ca. .
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3: Title: Mitochondrial regulation of cell cycle progression through SLC25A43.
Authors: Gabrielson, Marike, et.al. .
Journal: Biochemical and biophysical research communications (Biochem Biophys Res Commun), Vol. 469 (4): 1090-6, 2016 .
Snippet: In a previous study of HER2-positive tumours we could demonstrate a common loss in the gene encoding for the mitochondrial transporter SLC25A43 and also a significant relation between SLC25A43 protein expression and S-phase fraction.
Affiliation: School of Health and Medical Sciences, Faculty of Medicine and Health, Örebro University, SE 70182 Örebro, Sweden. Department of Clinical and Experimental Medicine, Linköping University, SE 58185 Linköping, Sweden; Department of Oncology, Linköping University, SE 58185 Linköping, Sweden. Department of Clinical Research Laboratory, Faculty of Medicine and Health, Örebro University, SE 70182 Örebro, Sweden. Electronic address: elisabet.tina@regionorebrolan.se. .
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4: Title: The mitochondrial solute carrier SLC25A5 at Xq24 is a novel candidate gene for non-syndromic intellectual disability.
Authors: Vandewalle, Joke, et.al. .
Journal: Human genetics (Hum Genet), Vol. 132 (10): 1177-85, 2013 .
Snippet: The smallest region of overlap, confirmed by junction sequencing, harbors two members of the mitochondrial solute carrier family 25, SLC25A5 and SLC25A43.
Affiliation: Human Genome Laboratory, VIB Center for the Biology of Disease, Leuven, Belgium. .
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5: Title: The mitochondrial transport protein SLC25A43 affects drug efficacy and drug-induced cell cycle arrest in breast cancer cell lines.
Authors: Gabrielson, Marike, et.al. .
Journal: Oncology reports (Oncol Rep), Vol. 29 (4): 1268-74, 2013 .
Snippet: Our findings demonstrate that the mitochondrial protein SLC25A43 affects drug efficacy and cell cycle regulation following drug exposure in breast cancer cell lines.
Affiliation: School of Health and Medical Sciences, Örebro University Hospital, SE-70185 Örebro, Sweden. marike.gabrielsson@oru.se .
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6: Title: Microduplication of Xq24 and Hartsfield syndrome with holoprosencephaly, ectrodactyly, and clefting.
Authors: Takenouchi, Toshiki, et.al. .
Journal: American journal of medical genetics. Part A (Am J Med Genet A), Vol. 158A (10): 2537-41, 2012 .
Snippet: Of the genes on the duplicated interval, the duplications of SLC25A43 and SLC25A5 appeared to be the most likely to explain the patient's phenotype.
Affiliation: Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan. .
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7: Title: The mitochondrial transporter SLC25A43 is frequently deleted and may influence cell proliferation in HER2-positive breast tumors.
Authors: Tina, Elisabet, et.al. .
Journal: BMC cancer, Vol. 12, 2012 .
Snippet: This locus harbors the gene solute carrier (SLC) family 25A member 43 (SLC25A43) encoding for a mitochondrial transport protein.
Affiliation: Clinical Research Centre, Örebro University Hospital, SE-70185, Örebro, Sweden. elisabet.tina@orebroll.se .
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8: Title: DNA methylation pattern of the SLC25A43 gene in breast cancer.
Journal: Epigenetics : official journal of the DNA Methylation Society (Epigenetics), Vol. 7 (3): 300-6, 2012 .
Snippet: Solute carrier family 25A member 43 (SLC25A43) gene is a putative tumor suppressor gene that undergoes loss of heterozygosity (LOH) in human epidermal growth factor receptor 2 (HER2) positive breast cancer.
Affiliation: School of Health and Medical Sciences, Örebro University, Örebro, Sweden. breezy.malakkaran-lindqvist@orebroll.se .
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9: Title: UBE2A deficiency syndrome: Mild to severe intellectual disability accompanied by seizures, absent speech, urogenital, and skin anomalies in male patients.
Authors: de Leeuw, Nicole, et.al. .
Journal: American journal of medical genetics. Part A (Am J Med Genet A), Vol. 152A (12): 3084-90, 2010 .
Snippet: We describe three patients with a comparable deletion encompassing SLC25A43, SLC25A5, CXorf56, UBE2A, NKRF, and two non-coding RNA genes, U1 and LOC100303728.
Affiliation: Department of Human Genetics, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. .
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10: Title: Fourteen novel human members of mitochondrial solute carrier family 25 (SLC25) widely expressed in the central nervous system.
Authors: Haitina, Tatjana, et.al. .
Journal: Genomics, Vol. 88 (6): 779-90, 2006 .
Snippet: These were provided with following gene symbols by the HGNC: SLC25A32, SLC25A33, SLC25A34, SLC25A35, SLC25A37, SLC25A38, SLC25A39, SLC25A40, SLC25A41, SLC25A42, SLC25A43, SLC25A44, SLC25A45, and SLC25A46.
Affiliation: Unit of Pharmacology, Department of Neuroscience, Uppsala University, BMC, Uppsala SE 75124, Sweden. .
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