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27 documents found
1: Title: WRKY7, -11 and -17 transcription factors are modulators of the bZIP28 branch of the unfolded protein response during PAMP-triggered immunity in Arabidopsis thaliana.
Authors: Arraño-Salinas, Paulina, et.al. .
Journal: Plant science : an international journal of experimental plant biology (Plant Sci), Vol. 277, 2018 .
Snippet: The bZIP28 TF upregulates ER-chaperone expression (BiP1/2, ERdj3B, and SDF2) upon exposure of Arabidopsis to a bacterial defense elicitor, flagellin 22 (Flg22).
Affiliation: Centro de Biotecnología Vegetal, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago, RM 837-0146, Chile. Centro de Biotecnología y Genómica de Plantas, Universidad Politécnica de Madrid (UPM) - Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Campus de Montegancedo, Autopista M40 (km 38), 28223 Madrid, Spain. Centro de Biotecnología Vegetal, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago, RM 837-0146, Chile; Millennium Institute for Integrative Systems and Synthetic Biology (MIISSB), Santiago, Chile. Centro de Biotecnología Vegetal, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago, RM 837-0146, Chile; FONDAP Center for Genome Regulation, Centro de Biotecnología Vegetal, Facultad de Ciencias de la Vida, Universidad Andres Bello, Avenida República 217, Santiago, RM 837-0146, Chile. Centro de Biotecnología Vegetal, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago, RM 837-0146, Chile. Electronic address: adrian.moreno@unab.cl. Centro de Biotecnología Vegetal, Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago, RM 837-0146, Chile; Millennium Institute for Integrative Systems and Synthetic Biology (MIISSB), Santiago, Chile. Electronic address: mblanco@unab.cl. .
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2: Title: Cerebrospinal Fluid Cytokine Expression Profile in Multiple Sclerosis and Chronic Inflammatory Demyelinating Polyneuropathy.
Authors: Bonin, Serena, et.al. .
Journal: Immunological investigations (Immunol Invest), Vol. 47 (2): 135-145, 2018 .
Snippet: CONCLUSIONS: Our study showed that, despite some common pathogenic mechanisms, central and peripheral nervous system demyelinating diseases, such as MS and CIDP, differ in some specific inflammatory soluble proteins in CSF, underlining differences in the immune response involved in those autoimmune diseases.
Affiliation: a Department of Medical Sciences , University of Trieste , Trieste , Italy. b Institute for Maternal and Child Health, IRCCS "Burlo Garofolo" , Trieste , Italy. c Unit of Neurology , Azienda Sanitaria Universitaria Integrata di Trieste , Trieste , Italy. .
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3: Title: Endoplasmic reticulum proteins SDF2 and SDF2L1 act as components of the BiP chaperone cycle to prevent protein aggregation.
Authors: Fujimori, Tsutomu, et.al. .
Journal: Genes to cells : devoted to molecular & cellular mechanisms (Genes Cells), Vol. 22 (8): 684-698, 2017 .
Snippet: Our findings indicate that SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins, partly explaining the broad folding capabilities of the ER under various physiological conditions.
Affiliation: Laboratory of Molecular and Cellular Biology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, 606-8507, Japan. Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, 606-8501, Japan. Translational Research Center, Fukushima Medical University, Fukushima, 960-8031, Japan. Molecular Profiling Research Center for Drug Discovery (molprof), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, 135-0064, Japan. Department of Cell Sciences, Institute of Biomedical Sciences, Fukushima Medical University School of Medicine, Fukushima, 960-1295, Japan. .
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4: Title: Stromal Cell-Derived Factor 2: A Novel Protein that Interferes in Endoplasmic Reticulum Stress Pathway in Human Placental Cells.
Authors: Lorenzon-Ojea, Aline R, et.al. .
Journal: Biology of reproduction (Biol Reprod), Vol. 95 (2): 41, 2016 .
Snippet: SDF2 downregulation was also followed by an increase in binding immunoglobulin protein (BiP) expression, an ER protein-associated chaperone acting as a sensor for misfolded proteins and an ER stress cell survival marker.
Affiliation: Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil Department of Obstetrics, Gynecology & Reproductive Sciences, School of Medicine, University of California San Francisco, San Francisco, California. Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, Brazil Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil. Department of Obstetrics, Gynecology & Reproductive Sciences, School of Medicine, University of California San Francisco, San Francisco, California. Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil bevilacq@usp.br. .
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5: Title: Protection of stromal cell-derived factor 2 by heat shock protein 72 prevents oxaliplatin-induced cell death in oxaliplatin-resistant human gastric cancer cells.
Authors: Takahashi, Katsuyuki, et.al. .
Journal: Cancer letters (Cancer Lett), Vol. 378 (1): 8-15, 2016 .
Snippet: Heat shock protein 72 (Hsp72) is a molecular chaperone that assists in the folding of nascent polypeptides and in the refolding of denatured proteins.
Affiliation: Department of Pharmacology, Osaka City University Medical School, Osaka, Japan; Department of Pharmacy, Osaka City University Hospital, Osaka, Japan. Applied Pharmacology and Therapeutics, Osaka City University Medical School, Osaka, Japan. Oncology Institute of Geriatrics and Medical Science, Osaka City University Graduate School of Medicine, Osaka, Japan. Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan. Department of Pharmacology, Osaka City University Medical School, Osaka, Japan. Department of Pharmacy, Osaka City University Hospital, Osaka, Japan. Department of Pharmacology, Osaka City University Medical School, Osaka, Japan; Applied Pharmacology and Therapeutics, Osaka City University Medical School, Osaka, Japan. Department of Pharmacology, Osaka City University Medical School, Osaka, Japan. Electronic address: sio@med.osaka-cu.ac.jp. .
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6: Title: Stromal cell-derived factor 2 is critical for Hsp90-dependent eNOS activation.
Authors: Siragusa, Mauro, et.al. .
Journal: Science signaling (Sci Signal), Vol. 8 (390): ra81, 2015 .
Snippet: In endothelial cells exposed to vascular endothelial growth factor (VEGF), SDF2 was required for the binding of Hsp90 and calmodulin to eNOS, resulting in eNOS phosphorylation and activation.
Affiliation: Vascular Biology and Therapeutics Program, Department of Pharmacology, Yale University School of Medicine, 10 Amistad Street, New Haven, CT 06520, USA. Department of Genetics and Complex Diseases, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA. Vascular Biology and Therapeutics Program, Department of Pharmacology, Yale University School of Medicine, 10 Amistad Street, New Haven, CT 06520, USA. william.sessa@yale.edu. .
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7: Title: Stromal cell derived factor-2 (Sdf2): a novel protein expressed in mouse.
Authors: Lorenzon-Ojea, Aline R, et.al. .
Journal: The international journal of biochemistry & cell biology (Int J Biochem Cell Biol), Vol. 53, 2014 .
Snippet: Comparing the amino acid sequence and predicted 3D structure with other Sdf2-like proteins we suggest a role of mouse Sdf2 in the Unfolded Protein Response and ER-stress, similar to that of Sdf2l1 from human and mouse and SDF2-like from Arabidopsis thaliana.
Affiliation: Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil. Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of São Paulo, São Paulo, Brazil. Department of Obstetrics, Gynecology & Reproductive Sciences, School of Medicine, University of California San Francisco, San Francisco, CA, USA. Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil. Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil. Electronic address: bevilacq@usp.br. .
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8: Title: Regulation of SOBIR1 accumulation and activation of defense responses in bir1-1 by specific components of ER quality control.
Authors: Sun, Tongjun, et.al. .
Journal: The Plant journal : for cell and molecular biology (Plant J), Vol. 77 (5): 748-56, 2014 .
Snippet: Here we report that mutations in three components of ER quality control, CALRETICULIN3 (CRT3), ER-LOCALIZED DnaJ-LIKE PROTEIN 3b (ERdj3b) and STROMAL-DERIVED FACTOR-2 (SDF2), also suppress the spontaneous cell death and constitutive defense responses in bir1-1.
Affiliation: Department of Botany, University of British Columbia, Vancouver, BC, Canada, V6T 1Z4. .
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9: Title: The endoplasmic reticulum-quality control component SDF2 is essential for XA21-mediated immunity in rice.
Authors: Park, Chang-Jin, et.al. .
Journal: Plant science : an international journal of experimental plant biology (Plant Sci), Vol. 210, 2013 .
Snippet: Silencing of the SDF2 genes in the XA21 rice genetic background compromises resistance to Xoo but does not affect plant growth and development.
Affiliation: Department of Plant Pathology and The Genome Center, University of California Davis, Davis, CA, United States. .
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10: Title: Protein O-mannosylation: what we have learned from baker's yeast.
Authors: Loibl, Martin, et.al. .
Journal: Biochimica et biophysica acta (Biochim Biophys Acta), Vol. 1833 (11): 2438-46, 2013 .
Snippet: In this review we summarize general features of protein O-mannosylation, including biosynthesis of the mannosyl donor, characteristics of acceptor substrates, and the protein O-mannosyltransferase machinery in the yeast ER.
Affiliation: University of Heidelberg, Heidelberg, Germany. .
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11: Title: The influence of environmental factors on the adhesion of combinations of probiotics to rice fibre fractions.
Journal: World journal of microbiology & biotechnology (World J Microbiol Biotechnol), Vol. 28 (6): 2293-302, 2012 .
Snippet: Nine co-cultures of the Bifidobacterium and Lactobacillus species were tested for their ability to adhere to insoluble dietary fibre (IDF1, IDF2), soluble dietary fibre (SDF1, SDF2), and total dietary fibre (TDF1, TDF2) from two rice varieties (RR1 and RR2).
Affiliation: Institute of Food Nutrition and Human Health, Massey University, Private Bag 11222, Palmerston North, New Zealand. binosha.fernando@gmail.com .
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12: Title: Identification of defense-related genes newly-associated with tomato flower abscission.
Authors: Meir, Shimon, et.al. .
Journal: Plant signaling & behavior (Plant Signal Behav), Vol. 6 (4): 590-3, 2011 .
Snippet: We identified four different defense-related genes, including: Cysteine-type endopeptidase, α-Dioxygenase 1 (α-DOX1), HopW-1-1-Interacting protein2 (WIN2), and Stomatal-derived factor-2 (SDF2), that are newly-associated with the late stage of the abscission process.
Affiliation: Department of Postharvest, ARO, The Volcani Center, Bet-Dagan, Israel. shimonm@volcani.agri.gov.il .
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13: Title: Methods to study stromal-cell derived factor 2 in the context of ER stress and the unfolded protein response in Arabidopsis thaliana.
Authors: Schott, Andrea, et.al. .
Journal: Methods in enzymology (Methods Enzymol), Vol. 490, 2011 .
Snippet: Most eukaryotes have two SDF2 homologous, whereas the model plant Arabidopsis thaliana has a single SDF2, thus representing an ideal model system to study the functional role of SDF2-type proteins.
Affiliation: Department of Cell Chemistry, Centre for Organismal Studies (COS), University of Heidelberg, Heidelberg, Germany. .
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14: Title: MPA-induced gene expression and stromal and parenchymal gene expression profiles in luminal murine mammary carcinomas with different hormonal requirements.
Journal: Breast cancer research and treatment (Breast Cancer Res Treat), Vol. 129 (1): 49-67, 2011 .
Snippet: Steap, Pdgfc, Runx2, Cxcl9, and Sdf2 were among the genes with high expression in the C4-HI tumor parenchyma.
Affiliation: Instituto de Biología y Medicina Experimental,Consejo Nacional de Investigaciones Científicas y Técnicas, C1428ADN, Buenos Aires, Argentina. .
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15: Title: Arabidopsis stromal-derived Factor2 (SDF2) is a crucial target of the unfolded protein response in the endoplasmic reticulum.
Authors: Schott, Andrea, et.al. .
Journal: The Journal of biological chemistry (J Biol Chem), Vol. 285 (23): 18113-21, 2010 .
Snippet: The increased production of SDF2 due to ER stress and in tissues that require enhanced protein biosynthesis and secretion, and its association with the ER membrane qualifies SDF2 as a downstream target of the UPR.
Affiliation: Department of Cell Chemistry, Institute for Plant Sciences, Im Neuenheimer Feld 360, University of Heidelberg, D-69120 Heidelberg, Germany. .
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16: Title: Cloning, recombinant production, crystallization and preliminary X-ray diffraction analysis of SDF2-like protein from Arabidopsis thaliana.
Authors: Radzimanowski, Jens, et.al. .
Journal: Acta crystallographica. Section F, Structural biology and crystallization communications (Acta Crystallogr Sect F Struct Biol Cryst Commun), Vol. 66 (Pt 1): 12-4, 2010 .
Snippet: The stromal-cell-derived factor 2-like protein of Arabidopsis thaliana (AtSDL) has been shown to be highly up-regulated in response to unfolded protein response (UPR) inducing reagents, suggesting that it plays a crucial role in the plant UPR pathway.
Affiliation: Heidelberg University Biochemistry Center (BZH), Im Neuenheimer Feld 328, D-69120 Heidelberg, Germany. .
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17: Title: Control of the pattern-recognition receptor EFR by an ER protein complex in plant immunity.
Authors: Nekrasov, Vladimir, et.al. .
Journal: The EMBO journal (Embo J), Vol. 28 (21): 3428-38, 2009 .
Snippet: SDF2 resides in an endoplasmic reticulum (ER) protein complex with the Hsp40 ERdj3B and the Hsp70 BiP, which are components of the ER-quality control (ER-QC).
Affiliation: The Sainsbury Laboratory, Norwich Research Park, Norwich, UK. .
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18: Title: Transcript analyses of stromal cell derived factors (SDFs): SDF-2, SDF-4 and SDF-5 reveal a different pattern of expression and prognostic association in human breast cancer.
Authors: Kang, Hua, et.al. .
Journal: International journal of oncology (Int J Oncol), Vol. 35 (1): 205-11, 2009 .
Snippet: It was found that SDF-2, SDF2-L1, SDF-4, and SDF-5 were ubiquitously expressed in various cancer cell lines.
Affiliation: Metastasis and Angiogenesis Research Group, Cardiff University School of Medicine, Cardiff CF14 4XN, UK. .
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19: Title: Genomic and transcriptomic prognostic factors in R0 Dukes B and C colorectal cancer patients.
Authors: Vendrell, Elisenda, et.al. .
Journal: International journal of oncology (Int J Oncol), Vol. 30 (5): 1099-107, 2007 .
Snippet: In transcriptomic analyses we identified 68 genes whose expression levels correlated with survival (p<0.01) and included overexpression of WASF1, NFE2L2, and MMP9, and underexpression of ITGAL, TSC2, and SDF2.
Affiliation: Institut d'Investigació Biomèdica de Bellvitge, L'Hospitalet, Barcelona, Catalonia, Spain. .
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20: Title: Specific integrin alpha and beta chain phosphorylations regulate LFA-1 activation through affinity-dependent and -independent mechanisms.
Authors: Fagerholm, Susanna C, et.al. .
Journal: The Journal of cell biology (J Cell Biol), Vol. 171 (4): 705-15, 2005 .
Snippet: In this study, we report that the phosphorylation of each cytoplasmic domain of the leukocyte function-associated antigen-1 integrin mediates different modes of integrin activation.
Affiliation: Division of Biochemistry, Faculty of Biosciences, University of Helsinki, FIN-00014 Helsinki, Finland. .
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