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15 documents found
1: Title: East Asian Genome-wide association study derived loci in relation to type 2 diabetes in the Han Chinese population.
Authors: Jamaspishvili, Esma, et.al. .
Journal: Acta biochimica Polonica (Acta Biochim Pol), 2019 .
Snippet: In quantitative trait analyses, WWOX rs17797882 was associated with decreased HOMA-β and increased level of TG and HDL-Ch, while PEPD rs3786897 and MAEA rs6815464 were associated with decreased fasting plasma glucose, and KCNK16 rs1535500 has shown a significant association with increased T-Ch and PSMD6 rs831571 had a significant association with decreased HDL-Ch.
Affiliation: Department of Endocrinology and Metabolism, The Second Affiliated Hospital, Harbin Medical University, Nangang District, Harbin, Heilongjiang, China. Epigenetic Department, Harbin Medical University, Nangang District, Harbin, Heilongjiang, China. .
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2: Title: Protein interactions of FAM134B with EB1 and APC/beta-catenin in vitro in colon carcinoma.
Authors: Islam, Farhadul, et.al. .
Journal: Molecular carcinogenesis (Mol Carcinog), 2018 .
Snippet: We have identified 29 novel binding partners, including CAP1, RPS28, FTH1, KDELR2, MAP4, EB1, PSMD6, PPIB/CYPB etc. Subsequent immunoassays confirmed the direct physical interactions of FAM134B with CAP1, EB1, CYPB, and KDELR2 in colon cancer cells.
Affiliation: Cancer Molecular Pathology, School of Medicine, Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia. Department of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi-6205, Bangladesh. Australian Rivers Institute & School of Environment, Griffith University, Gold Coast, Queensland, Australia. School of Medical Science, Griffith University, Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia. .
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3: Title: Gene co-expression network analysis for identifying genetic markers in Parkinson's disease - a three-way comparative approach.
Authors: George, Gincy, et.al. .
Journal: Genomics, 2018 .
Snippet: Of interest are three genes, eEF1A1, CASK, and PSMD6 that are linked to PARK2 activity in the cell and thereby form attractive candidate genes for understanding PD.
Affiliation: Department of Bioinformatics, Karunya University, Karunya Nagar, Tamil Nadu 641114, India. Department of Bioinformatics, Karunya University, Karunya Nagar, Tamil Nadu 641114, India; Institute of Bio-Sciences and Technology, Shri Ramswaroop Memorial University, Deva Road, Uttar Pradesh 225003, India. Department of Bioinformatics, Karunya University, Karunya Nagar, Tamil Nadu 641114, India; Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, CA 90033, USA. Electronic address: slokappa@usc.edu. Department of Bioinformatics, Karunya University, Karunya Nagar, Tamil Nadu 641114, India; Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, CA 90033, USA. Electronic address: jvarkey@usc.edu. .
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4: Title: Interplay between promoter methylation and chromosomal loss in gene silencing at 3p11-p14 in cervical cancer.
Authors: Lando, Malin, et.al. .
Journal: Epigenetics, Vol. 10 (10): 970-80, 2015 .
Snippet: Integrated analysis of methylation, gene dosage, and expression of the 26 hypermethylated genes identified 3 regulation patterns encompassing 8 hypermethylated genes; a methylation driven pattern (C3orf14, GPR27, ZNF717), a gene dosage driven pattern (THOC7, PSMD6), and a combined methylation and gene dosage driven pattern (FHIT, ADAMTS9, LRIG1).
Affiliation: a Department of Radiation Biology ; Norwegian Radium Hospital; Oslo University Hospital ; Oslo , Norway. b Department of Pathology ; VU University Medical Center ; Amsterdam , the Netherlands. c Department of Gynecologic Oncology ; Norwegian Radium Hospital; Oslo University Hospital ; Oslo , Norway. d Institute for Cancer Genetics and Informatics; Oslo University Hospital ; Oslo , Norway. e Faculty of Medicine; University of Oslo ; Oslo , Norway. .
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5: Title: A variant of PSMD6 is associated with the therapeutic efficacy of oral antidiabetic drugs in Chinese type 2 diabetes patients.
Authors: Chen, Miao, et.al. .
Journal: Scientific reports (Sci Rep), Vol. 5, 2015 .
Snippet: In conclusion, we observed that the PSMD6 variant rs831571 might be associated with the therapeutic effects of rosiglitazone and repaglinide in Chinese T2DM patients.
Affiliation: Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yishan Road, Shanghai, China. 1] Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Clinical Center for Diabetes, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yishan Road, Shanghai, China [2] Shanghai Jiao Tong University Affiliated Sixth People's Hospital South Campus, Shanghai, China. .
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6: Title: Increased New lncRNA-mRNA Gene Pair Levels in Human Cumulus Cells Correlate With Oocyte Maturation and Embryo Development.
Authors: Li, Juan, et.al. .
Journal: Reproductive sciences (Thousand Oaks, Calif.) (Reprod Sci), Vol. 22 (8): 1008-14, 2015 .
Snippet: Here, the expression of AK124742 and PSMD6 was measured in 40 pairs of cumulus cells from oocytes that result in high-quality embryos (HCCs) and from oocytes that result in poor-quality embryos (PCCs) by real-time quantitative reverse transcriptase polymerase chain reaction.
Affiliation: Reproductive Medicine Center, The First Affiliated Hospital, Anhui Medical University, Hefei, China. Reproductive Medicine Center, The First Affiliated Hospital, Anhui Medical University, Hefei, China caoyunxia6@126.com. .
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7: Title: A comparison of type 2 diabetes risk allele load between African Americans and European Americans.
Authors: Keaton, Jacob M, et.al. .
Journal: Human genetics (Hum Genet), Vol. 133 (12): 1487-95, 2014 .
Snippet: Risk alleles from 36 SNPs demonstrated directional consistency, and 10 SNPs from BCL11A, PSMD6, ADAMTS9, ZFAND3, ANK1, CDKN2A/B, TCF7L2, PRC1, FTO, and BCAR1 showed evidence of association (p < 0.05).
Affiliation: Molecular Genetics and Genomics Program, Wake Forest School of Medicine, Winston-Salem, NC, USA. .
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8: Title: Loss of urokinase receptor sensitizes cells to DNA damage and delays DNA repair.
Authors: Narayanaswamy, Pavan B, et.al. .
Journal: PloS one, Vol. 9 (7): e101529, 2014 .
Snippet: We further demonstrate that uPAR mediates DNA damage-induced phosphorylation, nuclear import, and recruitment of the regulatory subunit PSMD6 to proteasome.
Affiliation: Nephrology Department, Hannover Medical School, Hannover, Germany. .
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9: Title: Replication study for the association of 9 East Asian GWAS-derived loci with susceptibility to type 2 diabetes in a Japanese population.
Authors: Sakai, Kensuke, et.al. .
Journal: PloS one, Vol. 8 (9): e76317, 2013 .
Snippet: METHODS: We genotyped 7,379 Japanese participants (5,315 type 2 diabetes and 2,064 controls) for each of the 9 single nucleotide polymorphisms (SNPs), rs7041847 in GLIS3, rs6017317 in FITM2-R3HDML-HNF4A, rs6467136 near GCCI-PAX4, rs831571 near PSMD6, rs9470794 in ZFAND3, rs3786897 in PEPD, rs1535500 in KCNK16, rs16955379 in CMIP, and rs17797882 near WWOX.
Affiliation: Laboratory for Endocrinology, Metabolism and Kidney Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan ; Department of Internal Medicine, Division of Metabolism and Endocrinology, St. Marianna University School of Medicine, Kawasaki, Japan. .
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10: Title: Identification of eight candidate target genes of the recurrent 3p12-p14 loss in cervical cancer by integrative genomic profiling.
Authors: Lando, Malin, et.al. .
Journal: The Journal of pathology (J Pathol), Vol. 230 (1): 59-69, 2013 .
Snippet: We selected eight genes, THOC7, PSMD6, SLC25A26, TMF1, RYBP, SHQ1, EBLN2, and GBE1, which were highly down-regulated in cases with loss, as confirmed at the protein level for RYBP and TMF1 by immunohistochemistry.
Affiliation: Department of Radiation Biology, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway. .
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11: Title: Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
Authors: Cho, Yoon Shin, et.al. .
Journal: Nature genetics (Nat Genet), Vol. 44 (1): 67-72, 2012 .
Snippet: The combined analysis identified eight new T2D loci reaching genome-wide significance, which mapped in or near GLIS3, PEPD, FITM2-R3HDML-HNF4A, KCNK16, MAEA, GCC1-PAX4, PSMD6 and ZFAND3.
Affiliation: Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Cheongwon-gun, Gangoe-myeon, Yeonje-ri, Korea. yooncho33@korea.kr .
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12: Title: Effects of sex steroids on indices of protein turnover in rainbow trout (Oncorhynchusmykiss) white muscle.
Authors: Cleveland, Beth M, et.al. .
Journal: General and comparative endocrinology (Gen Comp Endocrinol), Vol. 174 (2): 132-42, 2011 .
Snippet: Single injections of E2 increased expression of ubiquitin ligase genes fbxo32, fbxo25, and murf1, and the proteasome subunit psmd6 by 24h after injection.
Affiliation: United States Department of Agriculture, Agricultural Research Service, National Center for Cool and Cold Water Aquaculture, 11861 Leetown Rd., Kearneysville, WV 25430, USA. beth.cleveland@ars.usda.gov .
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13: Title: Gene networks associated with conditional fear in mice identified using a systems genetics approach.
Authors: Park, Christopher C, et.al. .
Journal: BMC systems biology (Bmc Syst Biol), Vol. 5, 2011 .
Snippet: Highly connected genes in the context fear modules included Psmd6, Ube2a and Usp33, suggesting an important role for ubiquitination in learning and memory.
Affiliation: Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA. .
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14: Title: The ubiquitin proteasome system is required for cell proliferation of the lens epithelium and for differentiation of lens fiber cells in zebrafish.
Authors: Imai, Fumiyasu, et.al. .
Journal: Development (Cambridge, England) (Development), Vol. 137 (19): 3257-68, 2010 .
Snippet: We found that the vov mutant gene encodes Psmd6, the subunit of the 26S proteasome.
Affiliation: Developmental Neurobiology Unit, Okinawa Institute of Science and Technology (OIST), Onna, Okinawa, Japan. .
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15: Title: Karyotype variability in KP1(+) and KP1(-) strains of Trypanosoma rangeli isolated in Brazil and Colombia.
Journal: Acta tropica (Acta Trop), Vol. 110 (1): 57-64, 2009 .
Snippet: In the present study, the molecular karyotypes of 12 KP1(+) and KP1(-) Trypanosoma rangeli strains were determined and 10 different molecular markers were hybridized to the chromosomes of the parasite, including seven obtained from T. rangeli [ubiquitin hydrolase (UH), a predicted serine/threonine protein kinase (STK), hexose transporter, hypothetical protein, three anonymous sequences] and three from Trypanosoma cruzi [ubiquitin-conjugating enzyme E2 (UBE2), ribosomal RNA methyltransferase (rRNAmtr), proteasome non-ATPase regulatory subunit 6 (PSMD6)].
Affiliation: Departamento de Ciências Biológicas, Universidade Federal do Triângulo Mineiro, Av. Frei Paulino 30, Uberaba, Minas Gerais, Brazil. .
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