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2 documents found
1: Title: Largen: a molecular regulator of mammalian cell size control.
Authors: Yamamoto, Kazuo, et.al. .
Journal: Molecular cell (Mol Cell), Vol. 53 (6): 904-15, 2014 .
Snippet: We conducted a novel genetic screen to identify cell-size-controlling genes and isolated Largen, the product of a gene (PRR16) that increased cell size upon overexpression in human cells.
Affiliation: The Campbell Family Cancer Research Institute, Ontario Cancer Institute, University Health Network, Toronto, ON M5G 2C1, Canada; Departments of Medical Biophysics and Immunology, University of Toronto, Toronto, ON M5S 1A8, Canada. Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital, and Department of Oncology, McGill University, Montreal, QC H3T 1E2, Canada. Departments of Medical Biophysics and Immunology, University of Toronto, Toronto, ON M5S 1A8, Canada; Division of Signaling Biology, Ontario Cancer Institute, Toronto, ON M5G 1L7, Canada. Department of Neurology, Kurashiki Heisei Hospital, Kurashiki, Okayama 710-0826, Japan. The Campbell Family Cancer Research Institute, Ontario Cancer Institute, University Health Network, Toronto, ON M5G 2C1, Canada. Departments of Medical Biophysics and Immunology, University of Toronto, Toronto, ON M5S 1A8, Canada. Division of Cancer Genomics and Proteomics, Ontario Cancer Institute, Toronto, ON M5G 2M9, Canada. Department of Biochemistry, McGill University, Montreal, QC H3A 1A3, Canada. The Campbell Family Cancer Research Institute, Ontario Cancer Institute, University Health Network, Toronto, ON M5G 2C1, Canada; Departments of Medical Biophysics and Immunology, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: tmak@uhnresearch.ca. .
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2: Title: Maternal preconception body mass index and offspring cord blood DNA methylation: exploration of early life origins of disease.
Authors: Liu, Xin, et.al. .
Journal: Environmental and molecular mutagenesis (Environ Mol Mutagen), Vol. 55 (3): 223-30, 2014 .
Snippet: Some of the other CpG site annotated genes appear to be critical to the development of cancers and cardiovascular diseases (i.e., WNT16, C18orf8, ANGPTL2, SAPCD2, ADCY3, PRR16, ERBB2, DOK2, PLAC1).
Affiliation: Mary Ann and J. Milburn Smith Child Health Research Program, Ann & Robert H. Lurie Children's Hospital of Chicago Research Center, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois. .
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