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2 documents found
1: Title: Expression changes of cell-cell adhesion-related genes in colorectal tumors.
Authors: Bujko, Mateusz, et.al. .
Journal: Oncology letters (Oncol Lett), Vol. 9 (6): 2463-2470, 2015 .
Snippet: Between these tissue types, differences were observed in the mRNA levels of genes encoding adherens junction proteins (upregulation of CDH3 and CDH11, and downregulation of CDH19 and PTPRF), tight junction proteins (upregulation of CLDN1 and CLDN2, and downregulation of CLDN5, CLDN8, CLDN23, CLDN15, JAM2 and CGN) and desmosomes (upregulation of DSC3 and DSG3, and downregulation of DSC2), in addition to a decrease in the expression of certain other genes involved in intercellular connections: PCDHB14, PCDH7, MUPCDH and NEO1.
Affiliation: Department of Molecular and Translational Oncology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw 02-781, Poland. Department of Genetics, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw 02-781, Poland. Department of Pathology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw 02-781, Poland. .
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2: Title: PCDHB14- and GABRB1-like nervous system developmental genes are altered during early neuronal differentiation of NCCIT cells treated with ethanol.
Authors: Halder, D, et.al. .
Journal: Human & experimental toxicology (Hum Exp Toxicol), Vol. 34 (10): 1017-27, 2015 .
Snippet: EtOH exposure downregulated several important genes, such as PCDHB14, GABRB1, CTNND2, NAV3, RALDH1, and OPN5, which are involved in CNS development, synapse assembly, synaptic transmission, and neurotransmitter receptor activity.
Affiliation: Department of Molecular and Life Sciences, Hanyang University, Ansan, Republic of Korea. Department of Psychiatry, Gangnam Eulji Hospital, Eulji University, Seoul, Republic of Korea KARF Hospital, the Korean Alcohol Research Foundation, Goyang, Republic of Korea. KARF Hospital, the Korean Alcohol Research Foundation, Goyang, Republic of Korea. Institute of Natural Science and Technology, Hanyang University, Ansan, Republic of Korea ygchai@hanyang.ac.kr khjung2@gmail.com. Department of Molecular and Life Sciences, Hanyang University, Ansan, Republic of Korea Department of Nanobiotechnology, Hanyang University, Seoul, Republic of Korea ygchai@hanyang.ac.kr khjung2@gmail.com. .
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