refine search
Authors
Locations
Journals
Publication Dates
Find concepts in Knowledge Base
Explore current query
documentsstatisticstop authorclipboard
43 documents found
1: Title: Identification specific miRNA in t(4;14) multiple myeloma based on miRNA-mRNA expressing profile correlation analysis.
Authors: Liu, Huimin, et.al. .
Journal: Journal of cellular biochemistry (J Cell Biochem), 2018 .
Snippet: The miR-125a-3p, miR-125a-5p, miR-99b-5p, and let-7e were powerful miRNAs correlating with the FGFR3, MAP1B, MYRIP, and CDC42BPA under the relevance analysis in the subnetwork.
Affiliation: Department of Laboratory Medicine, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China. Medical School of Medicine, Nantong University, Nantong, Jiangsu, China. Clinical Biobank, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China. .
Related Products: order online
2: Title: Collaboration between Distinct Rab Small GTPase Trafficking Circuits Mediates Bacterial Clearance from the Bladder Epithelium.
Authors: Miao, Yuxuan, et.al. .
Journal: Cell host & microbe (Cell Host Microbe), Vol. 22 (3): 330-342.e4, 2017 .
Snippet: While RAB11a recruits its effector RAB11FIP3 and cytoskeletal motor Dynein, RAB27b mobilizes the effector MyRIP and motor Myosin VIIa to mediate bacterial expulsion.
Affiliation: Department of Molecular Genetics & Microbiology, Duke University Medical Center, Durham, NC 27710, USA. Electronic address: ymiao@rockefeller.edu. Program in Emerging Infectious Diseases, Duke-National University of Singapore, Singapore 169857, Singapore. Department of Immunology, Duke University Medical Center, Durham, NC 27710, USA. School of Law, Duke University, Durham, NC 27707, USA. Biomedical Analysis Center, Third Military Medical University, Chongqing 400038, China. Department of Molecular Genetics & Microbiology, Duke University Medical Center, Durham, NC 27710, USA; Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA; Department of Immunology, Duke University Medical Center, Durham, NC 27710, USA; Program in Emerging Infectious Diseases, Duke-National University of Singapore, Singapore 169857, Singapore. .
Related Products: order online
3: Title: Exophilin-8 assembles secretory granules for exocytosis in the actin cortex via interaction with RIM-BP2 and myosin-VIIa.
Authors: Fan, Fushun, et.al. .
Journal: eLife, Vol. 6, 2017 .
Snippet: Exophilin-8 has been reported to play a role in anchoring secretory granules within the actin cortex, due to its direct binding activities to Rab27 on the granule membrane and to F-actin and its motor protein, myosin-Va.
Affiliation: Laboratory of Molecular Endocrinology and Metabolism, Department of Molecular Medicine, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Japan. Animal Resource Development Unit, RIKEN Center for Life Science Technologies, Kobe, Japan. Genetic Engineering Team, RIKEN Center for Life Science Technologies, Kobe, Japan. Research Program for Signal Transduction, Division of Endocrinology, Metabolism and Signal Research, Gunma University Initiative for Advanced Research, Maebashi, Japan. .
Related Products: order online
4: Title: Interaction between MyRIP and the actin cytoskeleton regulates Weibel-Palade body trafficking and exocytosis.
Authors: Conte, Ianina L, et.al. .
Journal: Journal of cell science (J Cell Sci), Vol. 129 (3): 592-603, 2016 .
Snippet: To evaluate the specific contribution of MyRIP-actin and MyRIP-MyoVa binding in WPB trafficking and Ca(2+)-driven exocytosis, we used EGFP-MyRIP point mutants with disrupted MyoVa and/or actin binding and high-speed live-cell fluorescence microscopy.
Affiliation: Cardiovascular and Cell Science Research Institute, St George's University, London SW17 0RE, UK. The Francis Crick Institute, Mill Hill Laboratory, London NW7 1AA, UK. UMR144 CNRS/Institute Curie, Paris 75248, France. Cardiovascular and Cell Science Research Institute, St George's University, London SW17 0RE, UK tcarter@sgul.ac.uk. .
Related Products: order online
5: Title: Integrated microRNA-mRNA analysis of pancreatic ductal adenocarcinoma.
Authors: Liu, P F, et.al. .
Journal: Genetics and molecular research : GMR (Genet Mol Res), Vol. 14 (3): 10288-97, 2015 .
Snippet: The node degree of hsa-miR-200c, hsa-miR-429, and hsa-miR-200b (miRNA), and EFNB2, MYRIP, and PHF17 (mRNA) were extremely high in the miRNA-mRNA network, indicating that these miRNA and mRNA may play a key role in the development of pancreatic cancer.
Affiliation: Key Laboratory of Cancer Prevention and Therapy, Department of Lymphoma, Sino-US Center of Lymphoma and Leukemia, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China. Department of Radiotherapy, Second Hospital of Tianjin Medical University, Tianjin, China. Department of Cell Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China. Shanxi Agricultural University, Shanxi, China. Department of Gastrointestinal Surgery, Inner Mongolia People's Hospital, Hohhot, China snowlpf@163.com. .
Related Products: order online
6: Title: Rab27a GTPase modulates L-type Ca2+ channel function via interaction with the II-III linker of CaV1.3 subunit.
Authors: Reichhart, Nadine, et.al. .
Journal: Cellular signalling (Cell Signal), Vol. 27 (11): 2231-40, 2015 .
Snippet: Physical binding of heterologously expressed Rab27a with Ca(V)1.3 channels was shown by co-localization in immunocytochemistry as well as co-immunoprecipitation which was abolished after deletion of a MyRIP-homologous amino acid sequence at the II-III linker of the Ca(V)1.3
Affiliation: Experimental Ophthalmology, Eye Hospital, University Medical Center Regensburg, Regensburg, Germany; Experimental Ophthalmology, Eye Hospital, Charité University Medicine, Campus Virchow-Clinic, Berlin, Germany. Experimental Ophthalmology, Eye Hospital, Charité University Medicine, Campus Virchow-Clinic, Berlin, Germany. Experimental Ophthalmology, Eye Hospital, University Medical Center Regensburg, Regensburg, Germany. CEDOC, Faculdade de Ciências Médicas (FCM), Universidade Nova de Lisboa, Lisbon, Portugal. Experimental Ophthalmology, Eye Hospital, University Medical Center Regensburg, Regensburg, Germany; Department of Psychiatry and Psychotherapy, Molecular Neuroscience, University of Regensburg, Germany. Experimental Ophthalmology, Eye Hospital, University Medical Center Regensburg, Regensburg, Germany; Experimental Ophthalmology, Eye Hospital, Charité University Medicine, Campus Virchow-Clinic, Berlin, Germany. Electronic address: olaf.strauss@charite.de. .
Related Products: order online
7: Title: The circular RNA Cdr1as, via miR-7 and its targets, regulates insulin transcription and secretion in islet cells.
Authors: Xu, Huanyu, et.al. .
Journal: Scientific reports (Sci Rep), Vol. 5, 2015 .
Snippet: We further identified a new target Myrip in the Cdr1as/miR-7 pathway that regulates insulin granule secretion, and also another target Pax6 that enhances insulin transcription.
Affiliation: Institute of Genomic Medicine, Wenzhou Medical University, Zhejiang, China. Zhejiang Provincial Key Laboratory of Medical Genetics; School of Laboratory Medicine &Life Sciences, Wenzhou Medical University, Zhejiang, China. .
Related Products: order online
8: Title: Interplay between Rab27a effectors in pancreatic β-cells.
Authors: Yamaoka, Mami, et.al. .
Journal: World journal of diabetes (World J Diabetes), Vol. 6 (3): 508-16, 2015 .
Snippet: In pancreatic β-cells, GTP-bound Rab27a regulates insulin secretion at the pre-exocytotic stages via its GTP-specific effectors such as Exophilin8/Slac2-c/MyRIP and Slp4/Granuphilin.
Affiliation: Mami Yamaoka, Toshimasa Ishizaki, Toshihide Kimura, Department of Pharmacology, Oita University Faculty of Medicine, Oita 879-5593, Japan. .
Related Products: order online
9: Title: Identification of rare variants for hypertension with incorporation of linkage information.
Authors: Chiu, Yen-Feng, et.al. .
Journal: BMC proceedings (Bmc Proc), Vol. 8 (Suppl 1): S109, 2014 .
Snippet: DOCK3 and MYRIP are newly discovered.
Affiliation: Division of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes, 35 Keyan Rd., Zhunan, Miaoli 35053, Taiwan, ROC. Department of Biostatistics, Yale School of Public Health, 60 College Street, New Haven, Connecticut 06520, USA. Department of Biostatistical Sciences, Division of Public Health Sciences, 1834 Wake Forest Rd., Wake Forest School of Medicine, Winston-Salem, NC 27157, USA. .
Related Products: order online
10: Title: Copy number variation associated with meiotic arrest in idiopathic male infertility.
Authors: Eggers, Stefanie, et.al. .
Journal: Fertility and sterility (Fertil Steril), Vol. 103 (1): 214-9, 2015 .
Snippet: One containing the MYRIP gene and a second containing LRRC4C and the long noncoding RNA LOC100507205.
Affiliation: Murdoch Childrens Research Institute, Royal Children's Hospital and Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia. Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia. Centre for Genetic Diseases, Monash Institute of Medical Research, Monash University, Clayton, Victoria, Australia. Prince Henry's Institute of Medical Research and Department of Obstetrics and Gynaecology, Monash Medical Centre, Clayton, Victoria, Australia; Monash IVF, Richmond, Victoria, Australia. Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia. Electronic address: moira.obryan@monash.edu. .
Related Products: order online
11: Title: HIF1A as a major vascular endothelial growth factor regulator: do its polymorphisms have an association with age-related macular degeneration?
Authors: Okur, Volkan, et.al. .
Journal: Clinical & experimental ophthalmology (Clin Experiment Ophthalmol), Vol. 43 (1): 47-53, 2015 Jan-Feb .
Snippet: METHODS: Polymorphisms rs1061170 (CFH), rs429608 (SKIV2L), rs2679798 (MYRIP) and both rs11549465 and rs11549467 (HIF1A) were investigated in DNA isolated from peripheral blood samples of the cases and controls by dye-termination DNA sequencing.
Affiliation: Department of Medical Genetics, Medical School of Pamukkale University, Denizli, Turkey. .
Related Products: order online
12: Title: Circadian pathway genes in relation to glioma risk and outcome.
Authors: Madden, Melissa H, et.al. .
Journal: Cancer causes & control : CCC (Cancer Causes Control), Vol. 25 (1): 25-32, 2014 .
Snippet: Several of the examined genes exhibited differential expression in glioblastoma multiforme versus normal brain in TCGA data (MYRIP, ARNTL, CRY1, KLHL30, PER1, CLOCK, and PER3), and expression of NPAS2 was significantly associated with a poor patient outcome in TCGA patients.
Affiliation: Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL, 33612, USA. .
Related Products: order online
13: Title: An improved strategy for easy process monitoring and advanced purification of recombinant proteins.
Authors: Miladi, Baligh, et.al. .
Journal: Molecular biotechnology (Mol Biotechnol), Vol. 55 (3): 227-35, 2013 .
Snippet: In this work, a multifunctional expression cassette, termed Multitags, combining different and complementary functionalities, was designed and used to monitor the expression and the purification of two model proteins (Pfu DNA polymerase and Myosin-VIIa- and Rab-Interracting protein : MyRIP).
Affiliation: Laboratoire de Biologie Moléculaire, Ecole de Biologie Industrielle, 32 Boulevard du port, 95094, Cergy-Pontoise cedex, France. .
Related Products: order online
14: Title: MyRIP interaction with MyoVa on secretory granules is controlled by the cAMP-PKA pathway.
Authors: Brozzi, Flora, et.al. .
Journal: Molecular biology of the cell (Mol Biol Cell), Vol. 23 (22): 4444-55, 2012 .
Snippet: Glucose-stimulated insulin secretion is augmented by incretin hormones, which increase cAMP levels and leads to MyRIP phosphorylation, its interaction with BR-MyoVa, and phosphorylation of the BR-MyoVa receptor rabphilin-3A (Rph-3A).
Affiliation: Centre for Research in Biomedicine, Faculty of Health and Life Sciences, University of the West of England, Bristol BS16 1QY, United Kingdom. .
Related Products: order online
15: Title: The interplay between the Rab27A effectors Slp4-a and MyRIP controls hormone-evoked Weibel-Palade body exocytosis.
Authors: Bierings, Ruben, et.al. .
Journal: Blood, Vol. 120 (13): 2757-67, 2012 .
Snippet: siRNA knockdown of Slp4-a, MyRIP, Rab3B, Rab3D, Rab27A, or Rab3B/Rab27A, or overexpression of EGFP-Slp4-a or EGFP-MyRIP showed that Slp4-a is a positive and MyRIP a negative regulator of WPB exocytosis and that Rab27A alone mediates these effects.
Affiliation: Medical Research Council National Institute for Medical Research, The Ridgeway, London, United Kingdom. .
Related Products: order online
16: Title: Myrip couples the capture of secretory granules by the actin-rich cell cortex and their attachment to the plasma membrane.
Authors: Huet, Sébastien, et.al. .
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience (J Neurosci), Vol. 32 (7): 2564-77, 2012 .
Snippet: By combining total internal reflection fluorescence microscopy, single-particle tracking, a photoconversion-based assay, and mathematical modeling, we show that, in human enterochromaffin cells, Myrip (1) inhibits a class of SG motion characterized by fast and directed movement, suggesting that it facilitates the dissociation of SGs from microtubules; (2) enhances their motion toward the PM and the probability of SG attachment to the PM; and (3) increases the characteristic time of immobilization at the PM, indicating that it is a component of the molecular machinery that tether SGs to the PM.
Affiliation: Centre National de la Recherche Scientifique, UMR 6290, Institut Génétique et Développement de Rennes and Faculté de Médecine, Université Rennes 1, Université Européenne de Bretagne, Fédération de recherche Biosit, F-35043 Rennes, France. .
Related Products: order online
17: Title: Genes associated with recurrence of hepatocellular carcinoma: integrated analysis by gene expression and methylation profiling.
Authors: Yang, Ju Dong, et.al. .
Journal: Journal of Korean medical science (J Korean Med Sci), Vol. 26 (11): 1428-38, 2011 .
Snippet: The remaining 22 genes were defined as Group C. Complement factor H (CFH) and myosin VIIA and Rab interacting protein (MYRIP) in Group A; proline/serine-rich coiled-coil 1 (PSRC1), meiotic recombination 11 homolog A (MRE11A), and myosin IE (MYO1E) in Group B; and autophagy-related protein LC3 A (MAP1LC3A), and NADH dehydrogenase 1 alpha subcomplex assembly factor 1 (NDUFAF1) in Group C were validated.
Affiliation: Miles and Shirley Fiterman Center for Digestive Diseases, College of Medicine, Mayo Clinic, Rochester, MN, USA. .
Related Products: order online
18: Title: Identifying Tmem59 related gene regulatory network of mouse neural stem cell from a compendium of expression profiles.
Authors: Zhang, Luwen, et.al. .
Journal: BMC systems biology (Bmc Syst Biol), Vol. 5, 2011 .
Snippet: 16 out of 36 predicted genes in our constructed network have been reported to be AD-related, including Ace, aqp1, arrdc3, cd14, cd59a, cds1, cldn1, cox8b, defb11, folr1, gdi2, mmp3, mgp, myrip, Ripk4, rnd3, and sncg.
Affiliation: Laboratory of Molecular Neurobiology, Institute of Systems Biology, School of Life Sciences, Shanghai University, 99 Shangda Road, Shanghai 200433, China. .
Related Products: order online
19: Title: Myosin Va acts in concert with Rab27a and MyRIP to regulate acute von-Willebrand factor release from endothelial cells.
Authors: Rojo Pulido, Inés, et.al. .
Journal: Traffic (Copenhagen, Denmark) (Traffic), Vol. 12 (10): 1371-82, 2011 .
Snippet: These results indicate that a Rab27a/MyRIP/myosin Va complex is involved in linking WPB to the peripheral actin cytoskeleton of endothelial cells to allow full maturation and prevent premature secretion of vWF.
Affiliation: Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, University of Münster, Münster, Germany. .
Related Products: order online
20: Title: Cargo binding activates myosin VIIA motor function in cells.
Authors: Sakai, Tsuyoshi, et.al. .
Journal: Proceedings of the National Academy of Sciences of the United States of America (Proc Natl Acad Sci U S A), Vol. 108 (17): 7028-33, 2011 .
Snippet: These results suggest that association of myosin VIIA monomers with membrane via the MyRip/Rab27a complex facilitates the cargo-transporting activity of myosin VIIA, which is achieved by cluster formation on the membrane, where it possibly forms a dimer.
Affiliation: Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA 01655, USA. .
Related Products: order online
Page 1 2 3 
Documents per page: 20 | 50 | 100