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13 documents found
1: Title: Circulating MicroRNA in patients with repaired tetralogy of Fallot.
Authors: Lai, Clare T M, et.al. .
Journal: European journal of clinical investigation (Eur J Clin Invest), Vol. 47 (8): 574-582, 2017 .
Snippet: The study was conducted in two phases: (1) determination of circulating heart-related miRs described in left heart diseases (miR-1, miR-133a, miR-208a, miR-208b and miR423-5p) by quantitative real-time PCR in 49 patients and 30 controls and followed by validation in an independent cohort of 55 patients and 40 controls; (2) expression profiling of serum samples from eight patients and eight controls, followed by validation.
Affiliation: Division of Paediatric Cardiology, Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China. Department of Surgery, The University of Hong Kong, Hong Kong, China. .
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2: Title: Plasma micro-RNA biomarkers for diagnosis and prognosis after traumatic brain injury: A pilot study.
Authors: Mitra, Biswadev, et.al. .
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia (J Clin Neurosci), Vol. 38, 2017 .
Snippet: Two micro-RNAs, mir142-3p and mir423-3p demonstrated potential clinical utility differentiating patients after mild head injury into those at greater risk of developing amnesia and therefore, post-concussive syndromes.
Affiliation: Emergency & Trauma Centre, The Alfred Hospital, Australia; National Trauma Research Institute, The Alfred Hospital, Australia; Department of Epidemiology & Preventive Medicine, Monash University, Australia. Electronic address: biswadev.mitra@monash.edu. Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, MT, USA. National Trauma Research Institute, The Alfred Hospital, Australia. Emergency & Trauma Centre, The Alfred Hospital, Australia; National Trauma Research Institute, The Alfred Hospital, Australia. Glia Diagnostics, Australia. National Trauma Research Institute, The Alfred Hospital, Australia; Trauma Service, The Alfred Hospital, Australia. Department of Surgery, Monash University, Melbourne, Australia; Department of Neurosurgery, The Alfred Hospital, Melbourne, Australia; Department of Surgery, F. Edward Hébert School of Medicine, Uniformed Services University of The Health Sciences, Bethesda, MD, USA. .
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3: Title: Profiling cell-free and circulating miRNA: a clinical diagnostic tool for different cancers.
Authors: Chakraborty, Chiranjib, et.al. .
Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine (Tumour Biol), Vol. 37 (5): 5705-14, 2016 .
Snippet: Recent discoveries of novel cell-free and circulating miRNAs from the body fluids are now being considered as important biomarkers that may help us in the early diagnosis of any cancer.
Affiliation: Department of Bioinformatics, School of Computer and Information Sciences, Galgotias University, Uttar Pradesh, India. drchiranjib@yahoo.com. Department of Anatomy, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, 56000, Kuala Lumpur, Malaysia. drsrijit@gmail.com. .
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4: Title: Oncogenic role of microRNA-423-5p in hepatocellular carcinoma.
Authors: Wu, Li-Ming, et.al. .
Journal: Hepatobiliary & pancreatic diseases international : HBPD INT (Hepatobiliary Pancreat Dis Int), Vol. 14 (6): 613-8, 2015 .
Snippet: Cell viability assay, cell cycle analysis, transwell invasion and migration experiments were used to evaluate the oncogenic role of miR423-5p.
Affiliation: Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou 310003, China; Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health; Key Laboratory of Organ Transplantation of Zhejiang Province; Division of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China. shusenzheng@zju.edu.cn. .
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5: Title: Circulating MicroRNAs Characterizing Patients with Insufficient Coronary Collateral Artery Function.
Authors: Hakimzadeh, Nazanin, et.al. .
Journal: PloS one, Vol. 10 (9): e0137035, 2015 .
Snippet: We confirmed significantly elevated levels of miR423-5p (p<0.05),
Affiliation: Department of Biomedical Engineering & Physics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Department of Surgery, University Medical Center, Leiden, The Netherlands; Einthoven Laboratory for Experimental Vascular Medicine, Leiden, University Medical Center, Leiden, The Netherlands. Department of Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Department of Cardiology, Klinik für Innere Medizin III, Universität des Saarlandes, Homburg/Saar, Germany. Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Department of Cardiology, VU University Medical Center, Amsterdam, The Netherlands. Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands. .
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6: Title: The polymorphism of rs6505162 in the MIR423 coding region and recurrent pregnancy loss.
Authors: Su, Xing, et.al. .
Journal: Reproduction (Cambridge, England) (Reproduction), Vol. 150 (1): 65-76, 2015 .
Snippet: Collectively, the present data suggest that rs6505162 C>A in pre-MIR423 may contribute to the genetic predisposition to RPL by disrupting the production of mature MIR423 and its target gene, which consequently interferes with MIR423 functioning.
Affiliation: Reproductive and Genetic Center of National Research Institute for Family PlanningBeijing 100081, ChinaGraduate SchoolPeking Union Medical College, Beijing, China Reproductive and Genetic Center of National Research Institute for Family PlanningBeijing 100081, ChinaGraduate SchoolPeking Union Medical College, Beijing, China. Reproductive and Genetic Center of National Research Institute for Family PlanningBeijing 100081, ChinaGraduate SchoolPeking Union Medical College, Beijing, China Reproductive and Genetic Center of National Research Institute for Family PlanningBeijing 100081, ChinaGraduate SchoolPeking Union Medical College, Beijing, China genetic@126.com hongfeixia@126.com. .
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7: Title: MicroRNA-423-5p Promotes Autophagy in Cancer Cells and Is Increased in Serum From Hepatocarcinoma Patients Treated With Sorafenib.
Authors: Stiuso, Paola, et.al. .
Journal: Molecular therapy. Nucleic acids (Mol Ther Nucleic Acids), Vol. 4, 2015 .
Snippet: Secretory miR-423-5p was upregulated both in vitro and in vivo by sorafenib treatment and its increase was correlated with response to therapy since 75% of patients in which an increase of secretory miR423-5p was found were in partial remission or stable disease after 6 moths from the beginning of therapy.
Affiliation: Department of Biochemistry, Biophysics and General Pathology, Second University of Naples, Naples, Italy. Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Second University of Naples, Naples, Italy. Department of Biology, University "Federico II" of Naples, Naples, Italy. Medical Oncology Day Hospital Unit, San Giovanni di Dio Hospital, Naples, Italy. Department of Clinical and Experimental Medicine and Surgery, Second University of Naples, Naples, Italy. .
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8: Title: miR218-5p regulates the proliferation of gastric cancer cells by targeting TFF1 in an Erk1/2-dependent manner.
Authors: Shi, Ying, et.al. .
Journal: Biochimica et biophysica acta (Biochim Biophys Acta), Vol. 1852 (5): 970-9, 2015 .
Snippet: In an early study, we performed sequence analysis and identified one potential miR423-5p binding site within the 3'-untranslated region of TFF1 using microRNA target prediction tools.
Affiliation: Department of Gastroenterology, Zhongshan Hospital affiliated to Xiamen University, 201 Hubin South Road, Xiamen 361004, Fujian, China. Department of Gastroenterology, Zhongshan Hospital affiliated to Xiamen University, 201 Hubin South Road, Xiamen 361004, Fujian, China; Department of Gastroenterology, Xiamen Zhongshan Teaching Hospital of Fujian Medical University, Xiamen 361004, Fujian, China. Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung City 807, Taiwan; Division of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung City 812, Taiwan. Department of Gastroenterology, Zhongshan Hospital affiliated to Xiamen University, 201 Hubin South Road, Xiamen 361004, Fujian, China; Faculty of Clinical Medicine, Medical College of Xiamen University, 168 University Road, Xiamen 361005, Fujian, China; State Key Laboratory of Cellular Stress Biology, Xiamen University, 168 University Road, Xiamen 361005, Fujian, China. Electronic address: bayasi8@gmail.com. Department of Gastroenterology, Zhongshan Hospital affiliated to Xiamen University, 201 Hubin South Road, Xiamen 361004, Fujian, China. Electronic address: renjianl@xmu.edu.cn. .
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9: Title: Association between risk of oral precancer and genetic variations in microRNA and related processing genes.
Authors: Roy, Roshni, et.al. .
Journal: Journal of biomedical science (J Biomed Sci), Vol. 21, 2014 .
Snippet: Gene-environment interactions using MDR-pt program revealed that mir29a, mir34b, mir423 and Xpo5 modulated risk of disease (p < 0.002) which may be related to change in expression of these genes as observed by Real-Time PCR assays.
Affiliation: Human Genetics Unit, Indian Statistical Institute, 203, B,T, Road, Kolkata 700108, India. broy@isical.ac.in. .
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10: Title: Plasma miRNAs as Biomarkers to Identify Patients with Castration-Resistant Metastatic Prostate Cancer.
Authors: Watahiki, Akira, et.al. .
Journal: International journal of molecular sciences (Int J Mol Sci), Vol. 14 (4): 7757-70, 2013 .
Snippet: Pearson's correlation analysis revealed two highly correlated groups: one consisting of miR-141, miR375 and miR-200c and the other including miR151-3p, miR423-3p, miR-126, miR152 and miR-21.
Affiliation: The Vancouver Prostate Centre, Vancouver General Hospital, Vancouver, BC V6H 3Z6, Canada. chelgaso@bccrc.ca. .
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11: Title: Functionally orthologous viral and cellular microRNAs studied by a novel dual-fluorescent reporter system.
Authors: You, Xiangyu, et.al. .
Journal: PloS one, Vol. 7 (4): e36157, 2012 .
Snippet: Thus, this study presents a simple and universal system for testing miRNA function and identifies two new pairs of functional orthologs, sv40-mir-S1-5p and hsa-miR423-5p as well as hiv-1-miR-N367 and hsa-miR192.
Affiliation: State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China. .
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12: Title: MiR423-5p as a circulating biomarker for heart failure.
Authors: Tijsen, Anke J, et.al. .
Journal: Circulation research (Circ Res), Vol. 106 (6): 1035-9, 2010 .
Snippet: CONCLUSION: We identify 6 miRNAs that are elevated in patients with HF, among which miR423-5p is most strongly related to the clinical diagnosis of HF.
Affiliation: Heart Failure Research Center, Academic Medical Center, Meibergdreef 15, Amsterdam, The Netherlands. y.pinto@amc.uva.nl .
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13: Title: Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk.
Authors: Ye, Yuanqing, et.al. .
Journal: Cancer prevention research (Philadelphia, Pa.) (Cancer Prev Res (phila Pa)), Vol. 1 (6): 460-9, 2008 .
Snippet: The most notable finding was that the SNP rs6505162, which is located in the pre-mir423 region, was associated with a per-allele odds ratio of 0.64 [95% confidence interval (95% CI), 0.51-0.80;
Affiliation: Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. .
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