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5 documents found
1: Title: Selection and Application of Tissue microRNAs for Non-endoscopic Diagnosis of Barrett's Esophagus.
Authors: Li, Xiaodun, .
Journal: Gastroenterology, 2018 .
Snippet: Of these, 11 (MIR215, MIR194, MIR 192, MIR196a, MIR199b, MIR10a, MIR145, MIR181a, MIR30a, MIR7, and MIR199a) were validated in Cytosponge samples.
Affiliation: MRC Cancer Unit, Hutchison-MRC Research Centre, University of Cambridge, Cambridge, UK. Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA. Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK. Johns Hopkins Medical Institutions Deep Sequencing and Microarray Core, Baltimore, MD, USA. Cambridge University Hospitals NHS Trust, Cambridge UK. .
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2: Title: MicroRNA‑199b promotes cell proliferation and invasion in Wilms' tumour by directly targeting Runt‑related transcription factor 3.
Authors: Zhao, Huizhen, .
Journal: Molecular medicine reports (Mol Med Report), 2018 .
Snippet: The mechanisms underlying the action of miR‑199b in WT cells were also investigated using bioinformatics analysis, a luciferase reporter assay, RT‑qPCR and western blot analysis.
Affiliation: Department of Pediatrics, Yidu Central Hospital of Weifang, Weifang, Shandong 262550, P.R. China. Department of Pediatrics, Weifang People's Hospital, Weifang, Shandong 261000, P.R. China. .
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3: Title: MicroRNA-199b targets the regulation of ZEB1 expression to inhibit cell proliferation, migration and invasion in non‑small cell lung cancer.
Authors: Wang, Jin, .
Journal: Molecular medicine reports (Mol Med Report), Vol. 16 (4): 5007-5014, 2017 .
Snippet: In addition, zinc finger E‑box‑binding homeobox 1 (ZEB1) was identified to be a novel direct downstream and functional target for miR‑199b in NSCLC, using bioinformatics analysis, luciferase reporter assay, the reverse transcription‑quantitative polymerase chain reaction and western blotting.
Affiliation: Department of Thoracic Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116011, P.R. China. .
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4: Title: MiR199b suppresses expression of hypoxia-inducible factor 1α (HIF-1α) in prostate cancer cells.
Authors: Shang, Weiwei, .
Journal: International journal of molecular sciences (Int J Mol Sci), Vol. 14 (4): 8422-36, 2013 .
Snippet: Here we investigated the expression of miR199b and HIF-1α in normal prostate tissue, prostate cancer tissues and prostate carcinoma (PCa) cell lines LNCaP, PC-3 and DU145.We found that miR-199b expression level was decreased in prostate cancer while HIF-1α was significantly over-expressed.
Affiliation: Laboratory of Pathology, State Key Laboratory of Biotherapy and Department of Pathology, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, China. .
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5: Title: MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma.
Authors: Garzia, Livia, .
Journal: PloS one, Vol. 4 (3): e4998, 2009 .
Snippet: We further show that in a xenograft model, MB tumor burden can be reduced, indicating the use of miR199b-5p as an adjuvant therapy after surgery, in combination with radiation and chemotherapy, for the improvement of anti-cancer MB therapies and patient quality of life.
Affiliation: CEINGE, Centro di Ingegneria Genetica e Biotecnologia Avanzate, Naples, Italy. .
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