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6 documents found
1: Title: MIER3 suppresses colorectal cancer progression by down-regulating Sp1, inhibiting epithelial-mesenchymal transition.
Authors: Peng, Man, et.al. .
Journal: Scientific reports (Sci Rep), Vol. 7 (1): 11000, 2017 .
Snippet: Furthermore, our study showed that MIER3 inhibited cell proliferation and invasion partially via reduction of Sp1 and subsequent suppression of epithelial-mesenchymal transition (EMT).
Affiliation: Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China. Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China. geng@fimmu.com. Guangdong Provincial Key Laboratory of Molecular Oncologic Pathology, Southern Medical University, Guangzhou, 510515, China. geng@fimmu.com. Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. jzhou16@163.com. Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China. jzhou16@163.com. Guangdong Provincial Key Laboratory of Molecular Oncologic Pathology, Southern Medical University, Guangzhou, 510515, China. jzhou16@163.com. .
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2: Title: [Expression of MIER3 in colorectal cancer and bioinformatic analysis of MIER3- interacting proteins].
Authors: Song, Wen, et.al. .
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University (Nan Fang Yi Ke Da Xue Xue Bao), Vol. 37 (8): 1040-1046, 2017 .
Snippet: METHODS: MIER3 mRNA and protein expressions were detected in 8 CRC biopsy samples and paired adjacent tissues using real-time PCR and Western blotting.
Affiliation: Department of Pathology, Nanfang Hospital1, Department of Radiotherapy, Nanfang Hospital2, Department of Pathology, School of Basic Medical Sciences3, Southern Medical University, Guangzhou 510515, China. E-mail: sw890910@163.com. .
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3: Title: Differential HDAC1 and 2 Recruitment by Members of the MIER Family.
Authors: Derwish, Roya, et.al. .
Journal: PloS one, Vol. 12 (1): e0169338, 2017 .
Snippet: Histone deacetylase assays confirmed that MIER2, but not MIER3 complexes, have associated deacetylase activity, leading to the conclusion that MIER3 does not function in HDAC recruitment in these cell lines.
Affiliation: Terry Fox Cancer Research Laboratories, Division of BioMedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada. .
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4: Title: Does mouse embryo primordial germ cell activation start before implantation as suggested by single-cell transcriptomics dynamics?
Authors: Gerovska, Daniela, et.al. .
Journal: Molecular human reproduction (Mol Hum Reprod), Vol. 22 (3): 208-25, 2016 .
Snippet: We also identified new transitory E3.5 EPI markers (Sgk1, Mal, Ubxn2a, Atg16l2, Gm13102, Tcfap2c, Hexb, Slc1a1, Svip, Liph and Mier3), six new stable PE markers (Sdc4, Cpn1, Dkk1, Havcr1, F2r/Par1 and Slc7a6os) as well as three new stable EPI markers (Zp3, Mcf2 and Hexb), which are known to be late stage germ cell markers.
Affiliation: Group of Computational Biology and Systems Biomedicine, Biodonostia Health Research Institute, Calle Doctor Beguiristain s/n, 20014 San Sebastián - Donostia, Spain. Group of Computational Biology and Systems Biomedicine, Biodonostia Health Research Institute, Calle Doctor Beguiristain s/n, 20014 San Sebastián - Donostia, Spain IKERBASQUE, Basque Foundation for Science, Bilbao, Spain mararabra@yahoo.co.uk. .
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5: Title: Differential expression and prognostic role of selected genes in colorectal cancer patients.
Authors: Pitule, Pavel, et.al. .
Journal: Anticancer research (Anticancer Res), Vol. 33 (11): 4855-65, 2013 .
Snippet: Six genes were down-regulated: destrin (DSTN; p=0.004), mesoderm induction early response 1, family member 3 (MIER3; p<0.001), acyl-CoA synthetase long-chain family member 5 (ACSL5; p=0.002), mitogen-activated protein kinase 1/ERK (MAPK1; p<0.001), claudin 23 (CLDN23; p<0.001) and solute carrier family 26 (sulfate transporter), member 2 (SLC26A2; p<0.001).
Affiliation: Department of Histology and Embryology, Faculty of Medicine in Pilsen, Karlovarská 48, 301 00 Pilsen, Czech Republic. pitulep@seznam.cz. .
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6: Title: Rat Mcs1b is concordant to the genome-wide association-identified breast cancer risk locus at human 5q11.2 and MIER3 is a candidate cancer susceptibility gene.
Authors: denDekker, Aaron D, et.al. .
Journal: Cancer research (Cancer Res), Vol. 72 (22): 6002-12, 2012 .
Snippet: breast cancer risk allele marked by rs889312 is mammary gland autonomous, and MIER3 is a candidate breast cancer susceptibility gene.
Affiliation: Center for Genetics and Molecular Medicine, Department of Biochemistry and Molecular Biology, and James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky 40292, USA. .
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