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7 documents found
1: Title: N-acetylglucosaminyltransferases and nucleotide sugar transporters form multi-enzyme-multi-transporter assemblies in golgi membranes in vivo.
Authors: Khoder-Agha, Fawzi, et.al. .
Journal: Cellular and molecular life sciences : CMLS (Cell Mol Life Sci), 2019 .
Snippet: We show that MGAT1, MGAT2, MGAT3, MGAT4B (but not MGAT5) and Golgi alpha-mannosidase IIX (MAN2A2) form several distinct molecular assemblies with each other and that the MAN2A2 acts as a central hub for the interactions.
Affiliation: Faculty of Biochemistry and Molecular Medicine, University of Oulu, Aapistie 7A, 90220, Oulu, Finland. Laboratory of Biochemistry, Faculty of Biotechnology, University of Wroclaw, Wrocław, Poland. Human Genetics Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA. Faculty of Biology, University of Barcelona, Barcelona, Spain. Institute of Molecular Medicine, Helsinki, Finland. Faculty of Biochemistry and Molecular Medicine, University of Oulu, Aapistie 7A, 90220, Oulu, Finland. sakari.kellokumpu@oulu.fi. .
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2: Title: Understanding of decreased sialylation of Fc-fusion protein in hyperosmotic recombinant Chinese hamster ovary cell culture: N-glycosylation gene expression and N-linked glycan antennary profile.
Authors: Lee, Jong Hyun, et.al. .
Journal: Biotechnology and bioengineering (Biotechnol Bioeng), Vol. 114 (8): 1721-1732, 2017 .
Snippet: Addition of betaine, an osmoprotectant, to the hyperosmotic culture significantly increased the proportion of highly sialylated and tetra-antennary N-linked glycans (P ≤ 0.05), while it increased the expression of the N-glycan branching/antennary genes (mgat2 and mgat4b).
Affiliation: Department of Biological Sciences, KAIST, 335 Gwahak-ro, Yuseong-gu, Daejeon 305-701, Republic of Korea. Biotechnology Process Engineering Center, KRIBB, Ochang-eup, Cheongwon-gu, Cheongju, Republic of Korea. Department of Bioprocess Engineering, Korea University of Science and Technology (UST), Gajeong-ro, Yuseong-gu, Daejeon, Republic of Korea. .
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3: Title: GnT1IP-L specifically inhibits MGAT1 in the Golgi via its luminal domain.
Authors: Huang, Hung-Hsiang, et.al. .
Journal: eLife, Vol. 4, 2015 .
Snippet: GnT1IP-L did not generate a FRET signal with MGAT2, MGAT3, MGAT4B or MGAT5 medial Golgi GlcNAc-tranferases.
Affiliation: Department of Cell Biology, Albert Einstein College of Medicine, New York, United States. Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland. Andrology Division, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. .
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4: Title: UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats).
Journal: The Journal of biological chemistry (J Biol Chem), Vol. 290 (25): 15475-86, 2015 .
Snippet: In this study we analyzed whether NGT and both splice variants of UGT (UGT1 and UGT2) are able to interact with four different mannoside acetylglucosaminyltransferases (Mgat1, Mgat2, Mgat4B, and Mgat5).
Affiliation: From the Laboratories of Biochemistry and. Cytobiochemistry, Faculty of Biotechnology, University of Wroclaw, 50-383 Wroclaw, Poland. From the Laboratories of Biochemistry and Mariusz.Olczak@biotech.uni.wroc.pl. .
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5: Title: Altered N-Glycan expression profile in epithelial-to-mesenchymal transition of NMuMG cells revealed by an integrated strategy using mass spectrometry and glycogene and lectin microarray analysis.
Authors: Tan, Zengqi, et.al. .
Journal: Journal of proteome research (J Proteome Res), Vol. 13 (6): 2783-95, 2014 .
Snippet: The products of glycogenes ALG9, MGAT3, and MGAT4B appeared to contribute to the observed alteration of N-glycans.
Affiliation: The Key Laboratory of Carbohydrate Chemistry & Biotechnology, Ministry of Education; School of Biotechnology and ‡Wuxi Medical School, Jiangnan University , 1800 Lihu Avenue, Wuxi, Jiangsu 214122, China. .
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6: Title: Identification and characterization of genes that control fat deposition in chickens.
Authors: Claire D'Andre, Hirwa, et.al. .
Journal: Journal of animal science and biotechnology (J Anim Sci Biotechnol), Vol. 4 (1): 43, 2013 .
Snippet: Expression levels of genes for lipid metabolism (SULT1B1, ACSBG2, PNPLA3, LPL, AOAH) carbohydrate metabolism (MGAT4B, XYLB, GBE1, PGM1, HKDC1)cholesttrol biosynthesis (FDPS, LSS, HMGCR, NSDHL, DHCR24, IDI1, ME1) HSD17B7 and other reaction or processes (CYP1A4, CYP1A1, AKR1B1, CYP4V2, DDO) were higher in the fast-growing White Recessive Rock chickens than in the slow-growing Xinghua chickens.
Affiliation: Rwanda Agriculture Board, Research Department, P, O Box 5016, Kigali, Rwanda. chirwa02@yahoo.fr. .
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7: Title: Serum protein N-glycan alterations of diethylnitrosamine-induced hepatocellular carcinoma mice and their evolution after inhibition of the placental growth factor.
Authors: Blomme, Bram, et.al. .
Journal: Molecular and cellular biochemistry (Mol Cell Biochem), Vol. 372 (1-2): 199-210, 2013 .
Snippet: In addition, three Ets-1-dependent glycosyltransferase genes, Mgat4a, Mgat4b, and Mgat5, were also evaluated.
Affiliation: Department of Hepatology and Gastroenterology, Ghent University Hospital, 9000 Ghent, Belgium. bram.blomme@ugent.be .
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