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5 documents found
1: Title: Admixture Mapping of Subclinical Atherosclerosis and Subsequent Clinical Events Among African Americans in 2 Large Cohort Studies.
Authors: Shendre, Aditi, .
Journal: Circulation. Cardiovascular genetics (Circ Cardiovasc Genet), Vol. 10 (2), 2017 .
Snippet: We observed other cCIMT-LEA regions associated with other clinical events, most notably the regions harboring CKMT2 gene (creatine kinase, mitochondrial 2) and RASGRF2 gene (Ras protein-specific guanine nucleotide-releasing factor 2) with all clinical events except stroke, the LRRC3B gene (leucine-rich repeat containing 3B) with myocardial infarction, the PRMT3 gene (protein arginine methyltransferase 3) with stroke, and the LHFPL2 gene (lipoma high mobility group protein I-C fusion partner-like 2) with hard and all coronary heart disease.
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2: Title: Identification of genetic modifiers of age-at-onset for familial Parkinson's disease.
Authors: Hill-Burns, Erin M, .
Journal: Human molecular genetics (Hum Mol Genet), Vol. 25 (17): 3849-3862, 2016 .
Snippet: LHFPL2 (function unknown) is overexpressed in brain tumours.
Affiliation: Department of Neurology, University of Alabama at Birmingham, AL, USA. Department of Neuroscience, Mayo Clinic Jacksonville, FL, USA. Department of Molecular and Medical Genetics, Oregon Health & Sciences University, Portland, OR, USA. Department of Neurology, Medical University of Silesia, Katowice, Poland. Dublin Neurological Institute at the Mater Misericordiae University Hospital, Conway Institute of Biomolecular & Biomedical Research, University College Dublin, Ireland. Department of Neurology, Mayo Clinic Jacksonville, FL, USA. Eskitis Institute for Drug Discovery, Griffith University, Queensland, Australia. Department of Epidemiology, Fielding School of Public Health and Neurology, Geffen School of Medicine at UCLA, Los Angeles, CA, USA. The Neurogenomics Laboratory, Harvard Medical School and Brigham & Women's Hospital, Cambridge, MA, USA. VA Puget Sound Health Care System and Department of Neurology, University of Washington, Seattle, WA, USA. Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA. Department of Biostatistics, University of Iowa, Iowa City, IA, USA. Department of Neurology, University of Alabama at Birmingham, AL, USA Center for Genomic Medicine, HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA. .
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3: Title: Novel function of LHFPL2 in female and male distal reproductive tract development.
Authors: Zhao, Fei, .
Journal: Scientific reports (Sci Rep), Vol. 6, 2016 .
Snippet: A spontaneous point mutation of Lhfpl2 (LHFPL2(G102E)) leads to infertility in 100% female mice, which have normal ovarian development, ovulation, uterine development, and uterine response to exogenous estrogen stimulation, but abnormal upper longitudinal vaginal septum and lower vaginal agenesis.
Affiliation: Department of Physiology and Pharmacology, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA. Interdisciplinary Toxicology Program, University of Georgia, Athens, GA 30602, USA. .
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4: Title: Comparison of senescence-associated miRNAs in primary skin and lung fibroblasts.
Authors: Holly, Alice C, .
Journal: Biogerontology, Vol. 16 (4): 423-34, 2015 .
Snippet: LHFPL2 was also positively correlated with age in peripheral blood (p value = 6.6 × 10(-5)).
Affiliation: Institute of Biomedical and Clinical Sciences, University of Exeter Medical School, University of Exeter, Barrack Road, Exeter, Devon, EX1 2LU, UK. .
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5: Title: Identification of a subset of patients with acute myeloid leukemia characterized by long-term in vitro proliferation and altered cell cycle regulation of the leukemic cells.
Journal: Expert opinion on therapeutic targets (Expert Opin Ther Targets), Vol. 18 (11): 1237-51, 2014 .
Snippet: Patients with long-term proliferation showed altered expression in six cell cycle-related genes (HMMR, BUB1, NUSAP1, AURKB, CCNF, DLGAP5), two genes involved in DNA replication (TOP2A, RFC3) and one gene with unknown function (LHFPL2).
Affiliation: University of Bergen, Department of Clinical Science , Bergen , Norway. .
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