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1: Title: Germline genetics of cancer of unknown primary (CUP) and its specific subtypes.
Authors: Hemminki, Kari, .
Journal: Oncotarget, Vol. 7 (16): 22140-9, 2016 .
Snippet: For patients with liver metastases associations on chromosome 6 and 11, the latter including a cluster of genes DHCR7 and NADSYN1, encoding key enzymes in cholesterol and NAD synthesis, and KRTAP5-7, encoding a keratin associated protein.
Affiliation: Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. Center for Primary Health Care Research, Lund University, Malmö, Sweden. Department of Clinical Sciences, Clinical Research Center, Lund University, Malmö, Sweden. Department of Plastic and Reconstructive Surgery, Skane University Hospital, Malmö, Sweden. Department of Medical Biosciences/Pathology, University of Umea, Umea, Sweden. Clinical Pharmacology, Department of Pharmacology and Clinical Neuroscience, Umea University, Umea, Sweden. Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Medical Department I, University Hospital Carl Gustav Carus, University Cancer Center, Dresden, Germany. Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ) and Department of Medicine V, University of Heidelberg, Heidelberg, Germany. .
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