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11 documents found
1: Title: Trans-ethnic Evaluation Identifies Novel Low Frequency Loci Associated with 25-Hydroxyvitamin D Concentrations.
Authors: Hong, Jaeyoung, et.al. .
Journal: The Journal of clinical endocrinology and metabolism (J Clin Endocrinol Metab), 2018 .
Snippet: Conclusions: Ancestry-specific and trans-ethnic GWAS of 25(OH)D confirmed findings in GC and DHCR7 for African and Hispanic American samples and revealed novel findings near KIF4B, ANO6/ARID2, and HTR2A.
Affiliation: Department of Biostatistics, Boston University School of Public Health, Boston, MA. Department of Population Health Sciences, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI. Center for Applied Genomics, Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA. The Children's Hospital of Philadelphia, Philadelphia, PA. USDA-ARS Human Nutrition Research Center on Aging at Tufts University, Boston, MA. Wake Forest School of Medicine, Winston-Salem, NC. The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY. Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN. Department of Medicine, University of Mississippi Medical Center, Jackson, MS. Data Tecnica International, Glen Echo, MD. Laboratory of Neurogenetics, National Institute on Aging, NIH, Bethesda, MD. Kidney Research Institute, Division of Nephrology, Department of Medicine, University of Washington, Seattle, WA. Division of Endocrinology, Children's Hospital of Philadelphia, Philadelphia, PA. Department of Clinical Laboratory and Nutritional Sciences, University of Massachusetts Lowell, Lowell, MA. McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA. University of Texas Health Science Center at Houston, Houston, TX. Department of Radiology, Children's Hospital of Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA. Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC. Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH. Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA. Creighton University, Omaha, NE. Department of Epidemiology and Prevention, Division of Public Health Sciences Wake Forest School of Medicine, Winston-Salem, NC. Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins University School of Medicine, Baltimore, MD. Division of Pediatric Endocrinology, Diabetes and Metabolism, Columbia University Medical Center, New York, NY. Institute for Translational Genomics and Population Sciences, Department of Pediatrics and Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA. Department of Pediatrics, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK. University of California San Francisco School of Medicine, San Francisco, CA. Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS. Division of Biostatistics, University of Minnesota, Minneapolis, MN. Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD. The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY. Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora, CO. Nutrition and Genomics, JM-USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA. University of Washington and Department of Epidemiology and Health Sciences, University of Washington, Seattle, WA. Kaiser Permanente Washington Health Research Institute, Seattle, WA. Department of Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City, OK. Oklahoma Center for Neuroscience, Oklahoma City, OK. Division of General Internal Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA. National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA. Diabetes Unit, Massachusetts General Hospital, Boston, MA. Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA. Department of Medicine, Harvard Medical School, Boston, MA. Vanderbilt University, Nashville, TN, USA. NorthShore University HealthSystem Medical Group-Adult Endocrinology, Skokie, IL. University of Chicago Pritzker School of Medicine, Chicago, IL. .
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2: Title: Kinesin superfamily protein expression and its association with progression and prognosis in hepatocellular carcinoma.
Authors: Chen, Jianliang, et.al. .
Journal: Journal of cancer research and therapeutics (J Cancer Res Ther), Vol. 13 (4): 651-659, 2017 .
Snippet: KIF2A, KIF2C, KIF3A, KIF4B, KIF11, KIF15, KIFC1, and KIFC3 overexpression was associated with shorter overall survival (OS) times, whereas higher expression of KIF19 was associated with a longer OS time.
Affiliation: Department of General Surgery, People' Hospital, Jingjiang 214500; Department of Liver Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210009; Department of Liver Surgery, Key Laboratory of Living Donor Liver Transplantation of Ministry of Public Health, Nanjing 210009, China. Department of Liver Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210009; Department of Liver Surgery, Key Laboratory of Living Donor Liver Transplantation of Ministry of Public Health, Nanjing 210009, China. Department of Respiratory Medicine, Jinling Hospital, Nanjing 210002, Jiangsu Province, China. .
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3: Title: Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference.
Authors: Zhu, Changjun, et.al. .
Journal: Molecular biology of the cell (Mol Biol Cell), Vol. 16 (7): 3187-99, 2005 .
Snippet: Eg5 (a member of the kinesin-5 family), Kif2A (a member of the kinesin-13 family), and KifC1 (a member of the kinesin-14 family) are crucial for spindle formation; KifC1, MCAK (a member of the kinesin-13 family), CENP-E (a member of the kinesin-7 family), Kif14 (a member of the kinesin-3 family), Kif18 (a member of the kinesin-8 family), and Kid (a member of the kinesin-10 family) are required for chromosome congression and alignment; Kif4A and Kif4B (members of the kinesin-4 family) have roles in anaphase spindle dynamics; and Kif4A, Kif4B, MKLP1, and MKLP2 (members of the kinesin-6 family) are essential for cytokinesis.
Affiliation: The Burnham Institute, La Jolla, CA 92037, USA. .
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4: Title: Cell cycle-dependent translocation of PRC1 on the spindle by Kif4 is essential for midzone formation and cytokinesis.
Authors: Zhu, Changjun, et.al. .
Journal: Proceedings of the National Academy of Sciences of the United States of America (P Natl Acad Sci Usa), Vol. 102 (2): 343-8, 2005 .
Snippet: In this study, we report the use of time-lapse microscopy and a human kinesin endoribonucleases RNase III-prepared short interfering RNA (esiRNA) library to identify Kif4 as a motor protein that translocates PRC1, a spindle midzone-associated cyclin-dependent kinase substrate protein, to the plus ends of interdigitating spindle microtubules during the metaphase-to-anaphase transition.
Affiliation: Programs of Cancer Genetics and Epigenetics and Signal Transduction, The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA. .
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5: Title: KIF27 is one of orthologs for Drosophila Costal-2.
Authors: Katoh, Yuriko, et.al. .
Journal: International journal of oncology (Int J Oncol), Vol. 25 (6): 1875-80, 2004 .
Snippet: Phylogenetic analysis revealed that KIF27, Kif7, KIF4A, KIF4B and KIF21A constitute the KIF27 subfamily among mammalian Kinesin family.
Affiliation: M&M Medical BioInformatics, Hongo 113-0033, Japan. .
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6: Title: Human chromokinesin KIF4A functions in chromosome condensation and segregation.
Authors: Mazumdar, Manjari, et.al. .
Journal: The Journal of cell biology (J Cell Biol), Vol. 166 (5): 613-20, 2004 .
Snippet: Human KIF4A is an essential chromosome-associated molecular motor involved in faithful chromosome segregation.
Affiliation: National Cancer Institute, National Institutes of Health, Bldg. 41, Rm. B 507, 41 Library Dr., Bethesda, MD 20892, USA. mazumdam@mail.nih.gov .
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7: Title: Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery.
Authors: Geiman, Theresa M, et.al. .
Journal: Nucleic acids research (Nucleic Acids Res), Vol. 32 (9): 2716-29, 2004 .
Snippet: DNMT3B also interacts with histone deacetylase 1 (HDAC1), the co-repressor SIN3A and the ATP-dependent chromatin remodeling enzyme hSNF2H.
Affiliation: Epigenetic Gene Regulation and Cancer Section, LRBGE/NCI/NIH, Bethesda, MD 20892, USA. .
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8: Title: Association of human kinesin superfamily protein member 4 with BRCA2-associated factor 35.
Authors: Lee, Young Mi, et.al. .
Journal: The Biochemical journal (Biochem J), Vol. 374 (Pt 2): 497-503, 2003 .
Snippet: A large portion of human kinesin superfamily protein member 4 (KIF4) is associated with the nuclear matrix during the interphase, while a small portion is found in the cytoplasm.
Affiliation: Institute for Medical Sciences, School of Medicine, Ajou University, Suwon 442-749, South Korea. .
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9: Title: Human kinesin superfamily member 4 is dominantly localized in the nuclear matrix and is associated with chromosomes during mitosis.
Authors: Lee, Y M, et.al. .
Journal: The Biochemical journal (Biochem J), Vol. 360 (Pt 3): 549-56, 2001 .
Snippet: As an initial step to understand the function(s) of human KIF4, its subcellular localization in HeLa cells was examined by using immunocytochemical and subcellular fractionation methods, and it was found that most KIF4 is localized in the nucleus.
Affiliation: Institute for Medical Sciences, School of Medicine, Ajou University, Suwon 442-749, South Korea. .
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10: Title: Identification of the human homologue of mouse KIF4, a kinesin superfamily motor protein.
Authors: Oh, S, et.al. .
Journal: Biochimica et biophysica acta (Biochim Biophys Acta), Vol. 1493 (1-2): 219-24, 2000 .
Snippet: The nucleotide sequence of human KIF4 (hKIF4) comprised part of the 5' untranslated region (UTR), a long open reading frame (ORF) encoding 1232 amino acids, and the entire 3' UTR.
Affiliation: Institute for Medical Sciences, Ajou University, Suwon 442-749, South Korea. .
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11: Title: Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization.
Authors: Ha, M J, et.al. .
Journal: Cytogenetics and cell genetics (Cytogenet Cell Genet), Vol. 88 (1-2): 41-2, 2000 .
No Abstract available.
Affiliation: Institute for Medical Sciences, School of Medicine, Ajou University, Suwon, Korea. .
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