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2 documents found
1: Title: Mutational analysis of IZUMO1R in women with fertilization failure and polyspermy after in vitro fertilization.
Authors: Yu, Mengru, et.al. .
Journal: Journal of assisted reproduction and genetics (J Assist Reprod Genet), 2017 .
Snippet: RESULTS: Four rare single nucleotide polymorphisms (SNPs) of the IZUMO1R were identified among specimens from patients with fertilization failure and polyspermy but were absent in the 300 control subjects.
Affiliation: Center for Reproductive Medicine, Shandong University, Jinan, China. National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Jinan, China. The Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, China. Shandong Provincial Key Laboratory of Reproductive Medicine, Jinan, China. Center for Reproductive Medicine, Shandong University, Jinan, China. humangenetics2008@hotmail.com. National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Jinan, China. humangenetics2008@hotmail.com. The Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, China. humangenetics2008@hotmail.com. Shandong Provincial Key Laboratory of Reproductive Medicine, Jinan, China. humangenetics2008@hotmail.com. Center for Reproductive Medicine, School of Medicine, Ren Ji Hospital, Shanghai Jiao Tong University, Shanghai, China. Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, China. .
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2: Title: Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization.
Authors: Kato, Kazuki, et.al. .
Journal: Nature communications (Nat Commun), Vol. 7, 2016 .
Snippet: Sperm-egg fusion is the critical step in mammalian fertilization, and requires the interaction between IZUMO1 on the sperm surface and JUNO (also known as folate receptor (FR) 4 or IZUMO1R) on the egg surface.
Affiliation: Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan. Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan. PRESTO, JST, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan. .
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