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1: Title: Structure of an N276-Dependent HIV-1 Neutralizing Antibody Targeting a Rare V5 Glycan Hole Adjacent to the CD4 Binding Site.
Journal: Journal of virology (J Virol), Vol. 90 (22): 10220-10235, 2016 .
Snippet: The CAP257-RH1 monoclonal antibody was derived from the immunoglobulin-variable IGHV3-33 and IGLV3-10 genes and neutralized RHPA but not the transmitted/founder virus from donor CAP257.
Affiliation: Centre for HIV and STIs, National Institute for Communicable Diseases, National Health Laboratory Service, Johannesburg, South Africa. Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA. Institute of Infectious Disease and Molecular Medicine and Division of Medical Virology, University of Cape Town and National Health Laboratory Service, Cape Town, South Africa. South African National Bioinformatics Institute, University of the Western Cape, Cape Town, South Africa. Centre for the AIDS Programme of Research in South Africa, University of KwaZulu-Natal, Durban, South Africa. Department of Epidemiology, Columbia University, New York, New York, USA. Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA pdkwong@nih.gov lynnm@nicd.ac.za. Centre for HIV and STIs, National Institute for Communicable Diseases, National Health Laboratory Service, Johannesburg, South Africa pdkwong@nih.gov lynnm@nicd.ac.za. .
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