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10 documents found
1: Title: Genetic and enzymatic characterization of 3-O-sulfotransferase SNPs associated with Plasmodium falciparum parasitaemia.
Authors: Nguyen, Ngoc Thy, et.al. .
Journal: Glycobiology, 2018 .
Snippet: In addition to the SNPs rs28470223 (C > T) in the promoter region of both HS3ST3A1 and rs62636623 (Gly/Arg) in the stem region of HS3ST3B1, three missense mutations (rs62056073, rs61729712 and rs9906590) located within the catalytic sulfotransferase domain of 3-OST-B1 are linked and associated to P. falciparum parasitaemia.
Affiliation: Aix Marseille Univ, INSERM, TAGC, Marseille, France. CNRS, Aix Marseille Univ, AFMB, Marseille, France. Univ. Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France. .
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2: Title: Therapeutic Response to Paroxetine in Major Depressive Disorder Predicted by DNA Methylation.
Authors: Takeuchi, Naohiro, et.al. .
Journal: Neuropsychobiology, Vol. 75 (2): 81-88, 2017 .
Snippet: CONCLUSION: Our results suggest that patients' DNA methylation profile at specific genes such as PPFIA4 and HS3ST1 is associated with individual variations in therapeutic responses to paroxetine.
Affiliation: School of Pharmacy, Hyogo University of Health Sciences, Hyogo, Japan. .
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3: Title: Laboratory validation of formal concept analysis of the methylation status of microarray-detected genes in primary breast cancer.
Authors: Kassim, Samar K, et.al. .
Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine (Tumour Biol), Vol. 39 (6): 1010428317698390, 2017 .
Snippet: The methylation status of both genes was laboratory validated using methylation-based polymerase chain reaction in breast cancer subtypes luminal A (early stages) and luminal B (late stages) in comparison with benign conditions and normal breast to conclude their roles in tumor invasion and to validate the newly developed algorithm (formal concept analysis).
Affiliation: 1 Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt. 2 Institute of Statistical Studies and Researches, Cairo University, Giza, Egypt. .
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4: Title: The heparan sulfate sulfotransferase 3-OST3A (HS3ST3A) is a novel tumor regulator and a prognostic marker in breast cancer.
Authors: Mao, X, et.al. .
Journal: Oncogene, Vol. 35 (38): 5043-55, 2016 .
Snippet: Further, this interplay between HS and FGF-7 modulated downstream ERK, AKT and p38 cascades, suggesting that altering 3-O-sulfation affects FGFR2IIIb-mediated signaling.
Affiliation: UMR 7365 CNRS-Université de Lorraine (IMoPA), MolCelTEG Team and Glyco-Fluo platform, Biopôle, Campus Biologie-Santé, Faculté de Médecine, Université de Lorraine, Vandoeuvre-les-Nancy, France. Laboratory of Experimental Cancer Research, Luxembourg Institute of Health, Luxembourg, UK. Division of Cancer Research, Medical Research Institute, University of Dundee, Dundee, UK. Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada. Cellular and Tissular Core Imaging Facility, PTIBC IBISA Nancy, Vandoeuvre-lès-Nancy, France. INSERM U1019E11, Lille, France. MD Anderson Cancer Center, University of Texas, Houston, TX, USA. .
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5: Title: Placental expression of heparan sulfate 3-O-sulfotransferase-3A1 in normotensive and pre-eclamptic pregnancies.
Authors: Amraoui, F, et.al. .
Journal: Placenta, Vol. 36 (11): 1218-24, 2015 .
Snippet: HS3ST3A1 expression was positively correlated with neonatal birth weight in normotensive women (r = 0.35, p < 0.01) and inversely correlated with mean arterial pressure of women with pre-eclampsia (r = 0.32, p = 0.02).
Affiliation: Department of Vascular Medicine, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. Electronic address: f.amraoui@amc.nl. Department of Obstetrics and Gynaecology, Academic Medical Center, Amsterdam, The Netherlands; Reproductive Biology Laboratory, Academic Medical Center, Amsterdam, The Netherlands. Electronic address: h.hassanilahsinoui@amc.nl. Reproductive Biology Laboratory, Academic Medical Center, Amsterdam, The Netherlands. Electronic address: s.boussata@hotmail.com. Reproductive Biology Laboratory, Academic Medical Center, Amsterdam, The Netherlands. Electronic address: r.keijser@amc.nl. Reproductive Biology Laboratory, Academic Medical Center, Amsterdam, The Netherlands. Electronic address: g.j.veenboer@amc.nl. Department of Vascular Medicine, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. Electronic address: s.middeldorp@amc.nl. Department of Obstetrics and Gynaecology, Academic Medical Center, Amsterdam, The Netherlands. Electronic address: j.a.vanderpost@amc.nl. Department of Obstetrics and Gynaecology, Academic Medical Center, Amsterdam, The Netherlands; Reproductive Biology Laboratory, Academic Medical Center, Amsterdam, The Netherlands. Electronic address: c.ris@amc.nl. Reproductive Biology Laboratory, Academic Medical Center, Amsterdam, The Netherlands. Electronic address: g.b.afink@amc.nl. Department of Vascular Medicine, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. Electronic address: b.j.vandenborn@amc.nl. .
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6: Title: Establishment of a human lung cancer cell line with high metastatic potential to multiple organs: gene expression associated with metastatic potential in human lung cancer.
Authors: Nakano, Tetsuhiro, et.al. .
Journal: Oncology reports (Oncol Rep), Vol. 28 (5): 1727-35, 2012 .
Snippet: Expression of three upregulated genes (HRB-2, HS3ST3A1 and RAB7) was higher in human cancer tissue compared to normal lung tissue, while expression of EDG1, which was downregulated, was lower in the cancer tissue compared to the normal lung.
Affiliation: Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Gunma 371-8511, Japan. .
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7: Title: Genetic variations in genes involved in heparan sulphate biosynthesis are associated with Plasmodium falciparum parasitaemia: a familial study in Burkina Faso.
Authors: Atkinson, Alexandre, et.al. .
Journal: Malaria journal (Malar J), Vol. 11, 2012 .
Snippet: Interestingly, Hs3st3a1 and Hs3st3b1 encoding enzymes involved in the biosynthesis of heparan sulphate are located within a chromosomal region linked to Plasmodium chabaudi parasitaemia in mice.
Affiliation: UMR-TAGC, INSERM, Marseille F, France. .
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8: Title: A whole genome association study of mother-to-child transmission of HIV in Malawi.
Authors: Joubert, Bonnie R, et.al. .
Journal: Genome medicine (Genome Med), Vol. 2 (3): 17, 2010 .
Snippet: Carriers of the rs8069770 variant allele were associated with a lower risk of HIV MTCT (odds ratio = 0.27, 95% confidence interval = 0.14, 0.51), where rs8069770 is located within HS3ST3A1, a gene involved in heparan sulfate biosynthesis.
Affiliation: Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC 27599, USA. Department of Genetics, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA ; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC 27599, USA ; Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, NC 27599, USA. College of Medicine, University of Malawi, Blantyre, Malawi. Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC 27599, USA ; Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, NC 27599, USA. .
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9: Title: Regulation of CCR5 expression in human placenta: insights from a study of mother-to-child transmission of HIV in Malawi.
Authors: Joubert, Bonnie R, et.al. .
Journal: PloS one, Vol. 5 (2): e9212, 2010 .
Snippet: An incremental increase in CCR5 expression was observed for incremental increases in expression of two heparan sulfate genes involved in viral infection, HS3ST3A1 (beta = 0.27, 95% CI = 0.18, 0.35) and HS3ST3B1 (beta = 0.11, 95% CI = 0.06, 0.18).
Affiliation: Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United States of America. joubert.bonnie@epa.gov .
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10: Title: [Primary study on glycan structure in pathopoiesis mechanism of recurrent respiratory papillomatosis].
Authors: Wang, Jun, et.al. .
Journal: Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery (Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi), Vol. 43 (5): 355-9, 2008 .
Snippet: The expression of dolichyl-phosphate mannosyltransferase polypeptide 1 (DPM1), asparagine-linked glycosylation 1 homolog (ALG1), fucosyltransferase 8 (FUT8) and alpha-mannosidase 1A (MAN1A) were regulated and beta-hexosaminidase (HEXB), beta1-galactosidase (GLB1), exostoses 1 (EXT1), fucosyltransferase (FUT) reduced expression and heparan sulfate 3-O-sulfotransferase 1 (HS3ST3A1) increased expression.
Affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Key Laboratory of Otolaryngology Head and Neck Surgery, Ministry of Education, Beijing 100730, China. .
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