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3 documents found
1: Title: High diagnostic accuracy of histone H4-IgG autoantibodies in systemic lupus erythematosus.
Authors: Vordenbäumen, Stefan, et.al. .
Journal: Rheumatology (Oxford, England) (Rheumatology (oxford)), 2017 .
Snippet: Methods: IgG-autoantibodies to histones H4 (HIST1H4A), H2A type 2-A (HIST2H2AA3) and H2A type 2-C (HIST2H2AC) were measured along with a standard antibody (SA) set including SSA, SSB, Sm, U1-RNP and RPLP2 in a multiplex magnetic microsphere-based assay in 153 SLE patients [85% female, 41 (13.5) years] and 81 healthy controls [77% female, 43.3 (12.4) years].
Affiliation: Department of Rheumatology & Hiller Research Unit Rheumatology, Heinrich-Heine-University, Düsseldorf. Protagen AG, Dortmund, Germany. .
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2: Title: Host Transcription Profile in Nasal Epithelium and Whole Blood of Hospitalized Children Under 2 Years of Age With Respiratory Syncytial Virus Infection.
Authors: Do, Lien Anh Ha, et.al. .
Journal: The Journal of infectious diseases (J Infect Dis), Vol. 217 (1): 134-146, 2017 .
Snippet: Interferon-α/β, NOTCH1 signaling pathways and potential biomarkers HIST1H4E, IL7R, ISG15 in NP samples, or BCL6, HIST2H2AC, CCNA1 in blood are leading pathways and hub genes that were associated with both RSV load and severity.
Affiliation: Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Program, in partnership with the Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam. Murdoch Children's Research Institute, Melbourne, Australia. Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, United Kingdom. Children Hospital 1, Ho Chi Minh City, Vietnam. Children Hospital 2, Ho Chi Minh City, Vietnam. European Institute for Systems Biology and Medicine, Lyon, France. Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, The Netherlands. Genome Institute of Singapore. London School of Hygiene & Tropical Medicine, United Kingdom. .
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3: Title: The histone H2A isoform Hist2h2ac is a novel regulator of proliferation and epithelial-mesenchymal transition in mammary epithelial and in breast cancer cells.
Journal: Cancer letters (Cancer Lett), Vol. 396, 2017 .
Snippet: Hist2h2ac mRNA was increased by MEK(1/2) or PI3-K activation in HC11 and EpH4 mammary epithelial cells, and in MC4-L2 and T47-D breast cancer cells.
Affiliation: Mass Spectrometry Centre, Organic Chemistry and Natural Products Unit, Dep. of Chemistry, Universidade de Aveiro, Campus de Santiago, 3810-193, Aveiro, Portugal; Cancer Biology and Epigenetics Group, Portuguese Oncology Institute of Porto, 4200-072 Porto, Portugal. Mass Spectrometry Centre, Organic Chemistry and Natural Products Unit, Dep. of Chemistry, Universidade de Aveiro, Campus de Santiago, 3810-193, Aveiro, Portugal; Institute for Biomedicine -iBiMED, Department of Medical Sciences, University of Aveiro, Portugal. Department of Biology and Biochemistry, Center for Nuclear Receptors and Cell Signalling, University of Houston, Houston, TX 77204, USA. Mass Spectrometry Centre, Organic Chemistry and Natural Products Unit, Dep. of Chemistry, Universidade de Aveiro, Campus de Santiago, 3810-193, Aveiro, Portugal. Department of Pathology, Portuguese Oncology Institute of Porto, 4200-072 Porto, Portugal. Cancer Biology and Epigenetics Group, Portuguese Oncology Institute of Porto, 4200-072 Porto, Portugal; Department of Pathology, Portuguese Oncology Institute of Porto, 4200-072 Porto, Portugal; Department of Pathology and Molecular Immunology, Institute of Biomedical Sciences Abel Salazar (ICBAS) - University of Porto, 4050-313 Porto, Portugal. Department of Biology and Biochemistry, Center for Nuclear Receptors and Cell Signalling, University of Houston, Houston, TX 77204, USA; Science for Life Laboratory, Division of Proteomics, School of Biotechnology, KTH - Royal Institute of Technology, 171 21 Solna, Sweden; Department of Biosciences, Karolinska Institutet, Huddinge, Sweden. Cancer Biology and Epigenetics Group, Portuguese Oncology Institute of Porto, 4200-072 Porto, Portugal; Department of Pathology and Molecular Immunology, Institute of Biomedical Sciences Abel Salazar (ICBAS) - University of Porto, 4050-313 Porto, Portugal. Mass Spectrometry Centre, Organic Chemistry and Natural Products Unit, Dep. of Chemistry, Universidade de Aveiro, Campus de Santiago, 3810-193, Aveiro, Portugal; Institute for Biomedicine -iBiMED, Department of Medical Sciences, University of Aveiro, Portugal. Electronic address: luisa.helguero@ua.pt. .
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