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21 documents found
1: Title: GGNBP2 suppresses triple-negative breast cancer aggressiveness through inhibition of IL-6/STAT3 signaling activation.
Authors: Liu, Jingjing, et.al. .
Journal: Breast cancer research and treatment (Breast Cancer Res Treat), Vol. 174 (1): 65-78, 2019 .
Snippet: Furthermore, experimental overexpression of GGNBP2 in MDA-MB-231 and Cal51 cells suppresses cell proliferation, migration and invasion, reduces the cancer stem cell subpopulation, and promotes cell apoptosis in vitro as well as inhibits tumor growth in vivo.
Affiliation: The 3rd Department of Breast Cancer, Treatment and Research Center, China Tianjin Breast Cancer Prevention, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Huan Hu Xi Road, Ti Yuan Bei, He Xi District, Tianjin, 300060, People's Republic of China. Division of Cancer, Faculty of Medicine, Cancer Research Center, Imperial College London, Hammersmith Hospital Campus, London, W12 0NN, UK. The 3rd Department of Breast Cancer, Treatment and Research Center, China Tianjin Breast Cancer Prevention, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Huan Hu Xi Road, Ti Yuan Bei, He Xi District, Tianjin, 300060, People's Republic of China. yunhuihu200408@163.com. The 3rd Department of Breast Cancer, Treatment and Research Center, China Tianjin Breast Cancer Prevention, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Huan Hu Xi Road, Ti Yuan Bei, He Xi District, Tianjin, 300060, People's Republic of China. zhangjin@tjmuch.com. .
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2: Title: Ablation of Ggnbp2 impairs meiotic DNA double-strand break repair during spermatogenesis in mice.
Authors: Guo, Kaimin, et.al. .
Journal: Journal of cellular and molecular medicine (J Cell Mol Med), Vol. 22 (10): 4863-4874, 2018 .
Snippet: Gametogenetin (GGN) binding protein 2 (GGNBP2) is a zinc finger protein expressed abundantly in spermatocytes and spermatids.
Affiliation: Department of Andrology, The First Hospital of Jilin University, Changchun, China. Department of OB/GYN, University of Louisville School of Medicine, Louisville, KY, USA. Pediatrics Departments, University of Louisville School of Medicine, Louisville, KY, USA. Division of Life Sciences and Center for Nutrigenomics & Applied Animal Nutrition, Alltech Inc., Nicholasville, KY, USA. Central Laboratory, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, China. .
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3: Title: Integrative Analyses of De Novo Mutations Provide Deeper Biological Insights into Autism Spectrum Disorder.
Authors: Takata, Atsushi, et.al. .
Journal: Cell reports (Cell Rep), Vol. 22 (3): 734-747, 2018 .
Snippet: Screening of compounds altering the expression of genes hit by damaging DNMs reveals a global downregulating effect of valproic acid, a known risk factor for ASDs, whereas cardiac glycosides upregulate these genes.
Affiliation: Department of Human Genetics, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. Department of Human Genetics, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan; Clinical Research Institute, Kanagawa Children's Medical Center, 2-138-4 Mutsukawa, Minami-ku, Yokohama 232-8555, Japan. Department of Human Genetics, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan; Department of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. Department of Human Genetics, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan; Clinical Genetics Department, Yokohama City University Hospital, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. Department of Psychiatry, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan. Department of Neuropsychiatry, Hirosaki University Graduate School of Medicine, 5 Zaif-cho, Hirosaki 036-8562, Japan; Department of Psychiatry, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu 431-3192, Japan. Faculty of Sociology, Chukyo University, 101 Tokodachi, Kaizu-cho, Toyota 470-0393, Japan. Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako 351-0198, Japan. Department of Medical Genetics, Osaka Medical Center and Research Institute for Maternal and Child Health, 840 Murodo-cho, Izumi 594-1101, Japan. Hiroshima Municipal Center for Child Health and Development, 2-15-55 Hikarimachi, Higashi-ku, Hiroshima 732-0052, Japan. Molecular Research Center for Children's Mental Development, United Graduate School of Child Development, Osaka University, D3, 2-2 Yamadaoka, Suita 565-0871, Japan; Department of Psychiatry, Osaka University Graduate School of Medicine, D3, 2-2 Yamadaoka, Suita 565-0871, Japan. Department of Psychiatry, Osaka University Graduate School of Medicine, D3, 2-2 Yamadaoka, Suita 565-0871, Japan. Department of Pediatrics and Neonatology, Nagoya City University Graduate School of Medical Sciences, Kawasumi 1, Mizuho-cho, Mizuho-ku, Nagoya 467-8601, Japan. Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. Fukuoka Children's Hospital, 5-1-1 Kashiiteriha, Higashi-ku, Fukuoka 813-0017, Japan. Department of Pediatrics, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8666, Japan. Department of Pediatrics, Yamagata University Faculty of Medicine, 2-2-2 Iida-nishi, Yamagata 990-9585, Japan. Department of Pediatrics, Yamagata Prefectural Rehabilitation Center for Children with Disabilities, 3-7-1 Kawasaki, Kaminoyama, Yamagata 999-3145, Japan. Department of Pediatrics, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke 329-0498, Japan. Department of Pediatrics, Yokohama City University Medical Center, 4-57 Urafune, Minami-ku, Yokohama 232-0024, Japan. Department of Pediatrics, Nishi-Niigata Chuo National Hospital, 1-14-1 Masago, Nishi-ku, Niigata 950-2085, Japan. Departments of Pediatrics and Child Health, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Japan; Department of Pediatrics, St. Mary's Hospital, 422 Tsubukuhonmach, Kurume 830-8543, Japan. Laboratory for Molecular Dynamics of Mental Disorders, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan; Department of Life Sciences, Graduate School of Arts and Sciences, University of Tokyo, Tokyo 153-8902, Japan. Department of Life Sciences, Graduate School of Arts and Sciences, University of Tokyo, Tokyo 153-8902, Japan. Laboratory for Molecular Dynamics of Mental Disorders, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan. Department of Human Genetics, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan; Department of Obstetrics and Gynecology, Juntendo University Faculty of Medicine, Tokyo 113-8421, Japan. Department of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. Department of Psychiatry, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu 431-3192, Japan. Department of Human Genetics, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. Electronic address: naomat@yokohama-cu.ac.jp. .
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4: Title: Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis.
Authors: Benyamin, Beben, et.al. .
Journal: Nature communications (Nat Commun), Vol. 8 (1): 611, 2017 .
Snippet: In addition, GGNBP2 was identified using gene-based analysis and summary statistics-based Mendelian randomization analysis, although further replication is needed to confirm this result.
Affiliation: Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, 4072, Australia. Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, 4072, Australia. Department of Neurology, Peking University, Third Hospital, No. 49, North Garden Road, Haidian District, 100191, Beijing, China. University of Queensland Diamantina Institute, The University of Queensland, Translational Research Institute, Brisbane, Queensland, 4102, Australia. Institute of Health and Biomedical Innovation, Queensland University of Technology, Translational Research Institute, Brisbane, Queensland, 4102, Australia. Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, King's College London, London, WC2 R2LS, UK. Laboratory of Molecular and Statistical Genetics and State Key Laboratory of Developmental Biology of Freshwater Fish, College of Life Sciences, Hunan Normal University, Changsha, 410081, Hunan, China. Department of Global Biostatistics and Data Science, School of Public Health and Tropical Medicine, Center for Bioinformatics and Genomics, Tulane University, 1440 Canal St, Suite 2001, New Orleans, LA, 70112, USA. Department of Neurology, Royal Brisbane & Women's Hospital, Brisbane, Queensland, 4029, Australia. Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, New South Wales, 2109, Australia. Center of System Biomedical Sciences, University of Shanghai for Science and Technology, 334, Jungong Road, Yangpu District, 200093, Shanghai, China. Kenneth G. Jamieson Department of Neurosurgery, Royal Brisbane & Women's Hospital, Herston, Queensland, 4029, Australia. Division of Ophthalmic Genetics, Laboratory for Stem Cell and Retinal Regeneration, The Eye Hospital of Wenzhou Medical University, 325027, Wenzhou, China. Institute of Genomic Medicine, Wenzhou Medical University, 325027, Wenzhou, China. Department of Rheumatology and Immunology, Shanghai Changzheng Hospital, The Second Military Medical University, 200003, Shanghai, China. School of Biomedical Sciences, The University of Queensland, Brisbane, Queensland, 4072, Australia. Stacey MND Laboratory, Discipline of Pathology, Brain and Mind Centre, The University of Sydney, Sydney, New South Wales, 2006, Australia. The Centre for Advanced Imaging, The University of Queensland, Brisbane, Queensland, 4072, Australia. Department of Medicine, Faculty of Medicine and Health Sciences, Multidisciplinary Motor Neurone Disease Clinic, Macquarie University, Sydney, New South Wales, 2109, Australia. Centre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, The University of New South Wales, Sydney, New South Wales, 2052, Australia. Neuropsychiatric Institute, Prince of Wales Hospital, Randwick, New South Wales, 2031, Australia. Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, 3584 CG, Utrecht, The Netherlands. Institute of Mental Health, The Sixth Hospital, Peking University, 100191, Beijing, China. Key Laboratory of Mental Health, Ministry of Health & National Clinical Research Center for Mental Disorders, Peking University, 100191, Beijing, China. UQ Centre for Clinical Research, The University of Queensland, Royal Brisbane & Women's Hospital, Brisbane, Queensland, 4029, Australia. Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, 4072, Australia. naomi.wray@uq.edu.au. Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, 4072, Australia. naomi.wray@uq.edu.au. .
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5: Title: ZFP403, a novel tumor suppressor, inhibits the proliferation and metastasis in ovarian cancer.
Authors: Zhu, Zhihui, et.al. .
Journal: Gynecologic oncology (Gynecol Oncol), 2017 .
Snippet: Ectopic overexpression of ZFP403 in ovarian cancer cells dramatically suppressed cell proliferation by inducing cell cycle arrest at G2/M phase.
Affiliation: College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China. Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China. Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. Electronic address: xiechengying818@simm.ac.cn. College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China. Electronic address: zhj@zcmu.edu.cn. .
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6: Title: Ggnbp2 Null Mutation in Mice Leads to Male Infertility Due to a Defect at the Spermiogenesis Stage.
Authors: Liu, Lingyun, et.al. .
Journal: The American journal of pathology (Am J Pathol), 2017 .
Snippet: Adult Ggnbp2 null males were sterile with smaller testes and an azoospermic phenotype, while mutant females were fertile.
Affiliation: Department of Andrology, The First Hospital of Jilin University, Changchun, Jilin, China. OB/GYN. Anatomical Sciences & Neurobiology. Pediatrics Departments, University of Louisville School of Medicine, Louisville, Kentucky. Division of Life Sciences and Center for Nutrigenomics & Applied Animal Nutrition, Alltech Inc., Nicholasville, Kentucky. Central Laboratory, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, China. OB/GYN. Electronic address: zhenmin.lei@louisville.edu. .
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7: Title: A Genome-wide Expression Association Analysis Identifies Genes and Pathways Associated with Amyotrophic Lateral Sclerosis.
Authors: Du, Yanan, et.al. .
Journal: Cellular and molecular neurobiology (Cell Mol Neurobiol), 2017 .
Snippet: SMR single gene analysis identified one significant and four suggestive genes associated with ALS, including C9ORF72 (P value = 7.08 × 10(-6)), NT5C3L (P value = 1.33 × 10(-5)), GGNBP2 (P value = 1.81 × 10(-5)), ZNHIT3(P value = 2.94 × 10(-5)), and KIAA1600(P value = 9.97 × 10(-5)).
Affiliation: Key Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, Yan Ta West Road 76, Xi'an, 710061, People's Republic of China. Key Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, Yan Ta West Road 76, Xi'an, 710061, People's Republic of China. fzhxjtu@mail.xjtu.edu.cn. .
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8: Title: GGNBP2 is necessary for testis morphology and sperm development.
Authors: Chen, Anqi, et.al. .
Journal: Scientific reports (Sci Rep), Vol. 7 (1): 2998, 2017 .
Snippet: GGNBP2 has also been reported to be essential for pregnancy maintenance via regulation of trophoblast stem cells.
Affiliation: State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, 200433, P.R. China. Department of Anatomy and Molecular Embryology, Ruhr-University Bochum, Bochum, Germany. State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, 200433, P.R. China. kingbellchen@fudan.edu.cn. Department of Anatomy and Molecular Embryology, Ruhr-University Bochum, Bochum, Germany. beate.brand-saberi@rub.de. .
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9: Title: GGNBP2 Suppresses the Proliferation, Invasion, and Migration of Human Glioma Cells.
Authors: Zhan, Ao, et.al. .
Journal: Oncology research (Oncol Res), Vol. 25 (5): 831-842, 2017 .
Snippet: Mechanistically, we demonstrated that the PI3K/Akt and Wnt/β-catenin signaling pathways were suppressed by GGNBP2 overexpression.
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10: Title: GGNBP2 acts as a tumor suppressor by inhibiting estrogen receptor α activity in breast cancer cells.
Authors: Lan, Zi-Jian, et.al. .
Journal: Breast cancer research and treatment (Breast Cancer Res Treat), Vol. 158 (2): 263-76, 2016 .
Snippet: We further demonstrate that GGNBP2 protein physically interacts with ERα, inhibits E2-induced activation of estrogen response element-driven reporter activity, and attenuates ER target gene expression in T47D cells.
Affiliation: Division of Life Sciences, Center for Nutrigenomics & Applied Animal Nutrition, Alltech Inc., Nicholasville, KY, 40356, USA. The 3rd Department of Breast Cancer, National Clinical Research Center of Cancer, Tianjin Medical University Cancer Institute & Hospital, 500 South Preston Street, Hu-Xi District, 300060, Tianjin, People's Republic of China. Department of OB/GYN & Women's Health, University of Louisville Health Sciences Center, 500 South Preston Street, Louisville, KY, 40292, USA. Birth Defects Center, Department of Molecular, Cellular and Craniofacial Biology, University of Louisville Health Sciences Center, Louisville, KY, 40292, USA. Department of Biochemistry & Molecular Genetics, University of Louisville Health Sciences Center, Louisville, KY, 40292, USA. Department of Pediatrics, The University of Texas at Austin Dell Medical School, Austin, TX, 78712, USA. The 3rd Department of Breast Cancer, National Clinical Research Center of Cancer, Tianjin Medical University Cancer Institute & Hospital, 500 South Preston Street, Hu-Xi District, 300060, Tianjin, People's Republic of China. zhangjin@tjmuch.com. Department of OB/GYN & Women's Health, University of Louisville Health Sciences Center, 500 South Preston Street, Louisville, KY, 40292, USA. zhenmin.lei@louisville.edu. .
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11: Title: Ggnbp2 Is Essential for Pregnancy Success via Regulation of Mouse Trophoblast Stem Cell Proliferation and Differentiation.
Authors: Li, Shengqiang, et.al. .
Journal: Biology of reproduction (Biol Reprod), Vol. 94 (2): 41, 2016 .
Snippet: Our studies for the first time demonstrate that GGNBP2 is an essential factor for pregnancy success acting through the maintenance of a balance of TSC proliferation and differentiation during placental development.
Affiliation: Department of OB/GYN & Women's Health, University of Louisville School of Medicine, Louisville, Kentucky. Birth Defects Center, Department of Molecular, Cellular and Craniofacial Biology, University of Louisville School of Dentistry, Louisville, Kentucky. Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas. Division of Life Sciences and Center for Nutrigenomics & Applied Animal Nutrition, Alltech Inc., Nicholasville, Kentucky zlan@alltech.com. Department of OB/GYN & Women's Health, University of Louisville School of Medicine, Louisville, Kentucky zhenmin.lei@louisville.edu. .
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12: Title: Downregulation of tumor suppressor gene ribonuclease T2 and gametogenetin binding protein 2 is associated with drug resistance in ovarian cancer.
Authors: Yin, Fuqiang, et.al. .
Journal: Oncology reports (Oncol Rep), Vol. 32 (1): 362-72, 2014 .
Snippet: Using real-time quantitative polymerase chain reaction, in the present study we showed that RNASET2 and GGNBP2 mRNA levels were significantly lower in A2780-CBP (carboplatin-resistant) and A2780-DDP (cisplatin-resistant) ovarian cancer cells than in the parental A2780 cells and were downregulated in drug-resistant ovarian cancer tissues compared with their drug-sensitive counterparts.
Affiliation: Medical Scientific Research Centre, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China. Center for Translational Medicine, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China. Department of Gynecologic Oncology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P.R. China. Key Laboratory for High-Incidence Tumor Prevention and Treatment, Ministry of Education, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China. .
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13: Title: Knockdown of ZNF403 inhibits cell proliferation and induces G2/M arrest by modulating cell-cycle mediators.
Authors: Guan, Rui, et.al. .
Journal: Molecular and cellular biochemistry (Mol Cell Biochem), Vol. 365 (1-2): 211-22, 2012 .
Snippet: ZNF403, also known as GGNBP2 (gametogenetin binding protein 2), is a highly conserved gene implicated in spermatogenesis.
Affiliation: Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Xiangya Hospital and Cancer Research Institute, Central South University, Changsha 410008, Hunan Province, China. rui.guan@utoronto.ca .
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14: Title: Prenatally diagnosed 17q12 microdeletion syndrome with a novel association with congenital diaphragmatic hernia.
Authors: Hendrix, Nancy W, et.al. .
Journal: Fetal diagnosis and therapy (Fetal Diagn Ther), Vol. 31 (2): 129-33, 2012 .
Snippet: The deletion caused haploinsufficiency for 17 genes, including AATF, ACACA, DDX52, DUSP14, GGNBP2, HNF-1B, LHX1, PIGW, SYNRG, TADA2A, and ZNHIT3.
Affiliation: Magee-Womens Hospital, Pittsburgh, PA 15237, USA. hendrixnw@mail.magee.edu .
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15: Title: Characterization of a 7.6-Mb germline deletion encompassing the NF1 locus and about a hundred genes in an NF1 contiguous gene syndrome patient.
Authors: Pasmant, Eric, et.al. .
Journal: European journal of human genetics : EJHG (Eur J Hum Genet), Vol. 16 (12): 1459-66, 2008 .
Snippet: Interestingly, the centromeric breakpoint is located in intron 4 of the PIPOX gene (pipecolic acid oxidase; NM_016518) and the telomeric breakpoint in intron 5 of the GGNBP2 gene (gametogenetin binding protein 2; NM_024835) coding a transcription factor.
Affiliation: UMR745 INSERM, Université Paris Descartes, Faculté des Sciences Pharmaceutiques et Biologiques, Paris, France. eric.pasmant@etu.univ-paris5.fr .
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16: Title: [Screening the effective target sequences of laryngeal carcinoma related gene LCRG1].
Authors: Duan, Chao-Jun, et.al. .
Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences (Zhong Nan Da Xue Xue Bao Yi Xue Ban), Vol. 33 (6): 468-75, 2008 .
Snippet: The reconstructed pSuper 362,398,432,789,903,and pSuper vectors were transfected into Hela cell lines and selected with the appropriate drugs to get resistant and pool cells, respectively.
Affiliation: Key Laboratory of Cancer Proteomics, Ministry of Health of China, Xiangya Hospital, Central South University, Changsha 410008, China. .
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17: Title: Comparative proteomics analysis of the proteins associated with laryngeal carcinoma-related gene 1.
Authors: Zhang, Xiaopeng, et.al. .
Journal: The Laryngoscope (Laryngoscope), Vol. 116 (2): 224-30, 2006 .
Snippet: Most of the characterized proteins were characterized as the members of enzymes (phosphoglycerate mutase, manganese superoxide dismutase, and so on), transcription proteins (rho gdp dissociation inhibitor), and so on.
Affiliation: From Key Laboratory of Cancer Proteomics, Ministry of Health of China 'Xiangya Hospital, and the Cancer Research Institute, Central South University, Changsha, China. .
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18: Title: [Analysis of differential proteins in laryngeal carcinoma cell line Hep-2 with transfection of LCRG1].
Authors: Zhang, Xiao-Peng, et.al. .
Journal: Ai zheng = Aizheng = Chinese journal of cancer (Unknown Journal), Vol. 25 (1): 22-8, 2006 .
Snippet: CONCLUSIONS: In this study, 2-DE gels of Hep-2/LCRG1 cell line with high expression of LCRG1 mRNA and vector control Hep-2/pcDNA3.1(+)
Affiliation: Health Ministry Key Laboratory of Cancer Proteomics, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P. R. China. .
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19: Title: [Functions of FANCL in primordial germ cell formation and Fanconi anemia].
Authors: Zhao, Qing-Guo, et.al. .
Journal: Yi chuan xue bao = Acta genetica Sinica (Yi Chuan Xue Bao), Vol. 32 (9): 993-1000, 2005 .
Snippet: In the adult male, FANCL and a few testis-specific proteins, GGN1 (gametogenetin protein 1), GGNBP1 (gametogenetin binding protein 1), GGNBP2 and OAZ3 (ornithine decarboxylase antizyme 3) form a novel testis-specific complex functioning in spermatogenesis.
Affiliation: Beijing Institute of Biotechnology, Beijing 100071, China. drzhaoqg@hotmail.com .
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20: Title: Yeast two-hybrid screens imply that GGNBP1, GGNBP2 and OAZ3 are potential interaction partners of testicular germ cell-specific protein GGN1.
Authors: Zhang, Jin, et.al. .
Journal: FEBS letters (Febs Lett), Vol. 579 (2): 559-66, 2005 .
Snippet: We found that gametogenetin binding protein 1 (GGNBP1), gametogenetin binding protein 2 (GGNBP2) and ornithine decarboxylase antizyme 3 (OAZ3) were potential GGN1 interaction partners.
Affiliation: Beijing Institute of Biotechnology, Beijing 100071, PR China. .
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