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21 documents found
1: Title: Cancer/testis antigens expression and autologous serological response in a set of Brazilian non-Hodgkin's lymphoma patients.
Authors: Inaoka, Riguel J, et.al. .
Journal: Cancer immunology, immunotherapy : CII (Cancer Immunol Immunother), Vol. 61 (12): 2207-14, 2012 .
Snippet: We aim to evaluate the expression of CTAs in non-Hodgkin's lymphoma (NHL) samples and the ability of these patients to elicit spontaneous humoral immune response against CTAs.
Affiliation: Departamento de Oncologia Clinica e Experimental, Universidade Federal de Sao Paulo, Rua Botucatu, 740, 3° andar, Hematologia, Vila Clementino, Sao Paulo, SP, 04023-900, Brazil. rigueljun@yahoo.com.br .
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2: Title: Expression of tumor-specific antigen MAGE, GAGE and BAGE in ovarian cancer tissues and cell lines.
Authors: Zhang, Shiqian, et.al. .
Journal: BMC cancer, Vol. 10, 2010 .
Snippet: Tumor-specific antigen MAGE may play a role in the occurrence and development of ovarian cancer and can be used as one of the important indicators for early diagnosis, efficacy evaluation and prognostic determination of ovarian cancer.
Affiliation: The State-Key Discipline of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Ji'nan 250012, China. zhangshiqian370112@126.com .
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3: Title: Yeast-based identification of prostate tumor antigens provides an effective vaccine platform.
Authors: Jung, Volker, et.al. .
Journal: Anticancer research (Anticancer Res), Vol. 30 (3): 895-902, 2010 .
Snippet: PATIENTS AND METHODS: We investigated the antibody response in 181 patients with prostate cancer, 83 benign prostate hyperplasia (BPH) patients, and 39 healthy donors against 13 different CT antigens recombinantly expressed on yeast surface (RAYS) and compared the results to antigen expression in tumor tissue.
Affiliation: University Hospital Zurich, Department of Oncology, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland. .
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4: Title: Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells.
Authors: Sun, Feng, et.al. .
Journal: Molecular cancer therapeutics (Mol Cancer Ther), Vol. 8 (12): 3191-202, 2009 .
Snippet: Through genome-wide gene expression analysis, coupled with extensive chromatin immunoprecipitation analysis of histone modifications, we have identified a variety of gene sets that are regulated either by EZH2 alone or through the coordinated action of EZH2 with HDAC and/or DNA methylation.
Affiliation: Cancer Biology and Pharmacology, Genome Institute of Singapore, 60 Biopolis Street, #02-01 Genome, Singapore 138672. .
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5: Title: Cancer-germline gene expression in pediatric solid tumors using quantitative real-time PCR.
Authors: Jacobs, Joannes F M, et.al. .
Journal: International journal of cancer. Journal international du cancer (Int J Cancer), Vol. 120 (1): 67-74, 2007 .
Snippet: Nine tumors were also examined by immunohistochemistry with monoclonal antibodies specific for the MAGE-A1, MAGE-A4 and NY-ESO-1 proteins.
Affiliation: Department of Pediatric Hemato-Oncology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. .
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6: Title: Analysis of the tumour suppressor genes, FHIT and WT-1, and the tumour rejection genes, BAGE, GAGE-1/2, HAGE, MAGE-1, and MAGE-3, in benign and malignant neoplasms of the salivary glands.
Authors: Nagel, H, et.al. .
Journal: Molecular pathology : MP (J Clin Pathol-mol Pa), Vol. 56 (4): 226-31, 2003 .
Snippet: This study aimed to analyse the expression of putative tumour suppressor genes, FHIT and WT-1, and tumour rejection genes, BAGE, GAGE-1/2, MAGE-1, MAGE-3, and HAGE (which are reported to be important in human cancers), in salivary gland neoplasms.
Affiliation: Department of Cytopathology, Georg-August-University of Göttingen, Robert-Koch-Straszligbeta;e 40, D-37075 Göttingen, Germany. hnagel@med.uni-goettingen.de .
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7: Title: mRNA detection of tumor-rejection genes BAGE, GAGE, and MAGE in peritoneal fluid from patients with ovarian carcinoma as a potential diagnostic tool.
Authors: Hofmann, Manfred, et.al. .
Journal: Cancer, Vol. 96 (3): 187-93, 2002 .
Snippet: Detection of tumor specific gene expression may be a sensitive additional tool in these settings.
Affiliation: Department of Pathology, Division of Cytopathology, Georg-August University, Goettingen, Germany. mhofmann@med.uni-goettingen.de .
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8: Title: MAGE, BAGE and GAGE gene expression in human rhabdomyosarcomas.
Authors: Dalerba, P, et.al. .
Journal: International journal of cancer. Journal international du cancer (Int J Cancer), Vol. 93 (1): 85-90, 2001 .
Snippet: Using RT-PCR, we analyzed MAGE-1, MAGE-2, MAGE-3, MAGE-4, MAGE-6, BAGE, GAGE-1,-2 or -8 and GAGE-3,-4,-5,-6 or -7b gene expression in 31 samples of pediatric rhabdomyosarcoma, the most frequent form of malignant soft tissue tumor in children.
Affiliation: Oncology Section, Department of Oncology and Surgical Sciences, University of Padua, Padua, Italy. .
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9: Title: Relationship between GAGE-1/-2 expression, EBV infection and interferon-gamma expression in undifferentiated carcinoma of nasopharyngeal type.
Authors: Schlott, T, et.al. .
Journal: Anticancer research (Anticancer Res), Vol. 20 (3A): 1727-32, 2000 May-Jun .
Snippet: The objective of the present study was to identify the existence of a relationship between GAGE-1/-2 expression, Epstein Barr Virus (EBV) infection and viral infection-induced cytokine expression in cultivated tumour cells and archival specimens of undifferentiated carcinoma of nasopharyngeal type (UCNT).
Affiliation: Department of Cytopathology, Georg-August-University, Goettingen, Germany. .
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10: Title: Vaccination of melanoma patients with an allogeneic, genetically modified interleukin 2-producing melanoma cell line.
Authors: Osanto, S, et.al. .
Journal: Human gene therapy (Hum Gene Ther), Vol. 11 (5): 739-50, 2000 .
Snippet: Thirty-three metastatic melanoma patients were vaccinated according to a phase I-II study with an allogeneic melanoma cell line that was genetically modified by transfection with a plasmid containing the gene encoding human interleukin 2 (IL-2).
Affiliation: Department of Clinical Oncology, Leiden University Medical Center, The Netherlands. osanto@mail.medfac.LeidenUniv.nl .
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11: Title: The cancer germ-line genes MAGE-1, MAGE-3 and PRAME are commonly expressed by human myeloma cells.
Authors: Pellat-Deceunynck, C, et.al. .
Journal: European journal of immunology (Eur J Immunol), Vol. 30 (3): 803-9, 2000 .
Snippet: In this study, we have investigated the mRNA expression of the cancer germ-line genes MAGE, BAGE, GAGE, RAGE and the tumor-overexpressed gene PRAME by human myeloma cell lines and malignant plasma cells from patients with multiple myeloma (MM).
Affiliation: Inserm U463, Institut de Biologie, Nantes, France. cpellat@nantes.inserm.fr .
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12: Title: MAGE-1, GAGE-1/-2 gene expression in FNAB of classic variant of papillary thyroid carcinoma and papillary hyperplasia in nodular goiter.
Authors: Ruschenburg, I, et.al. .
Journal: International journal of molecular medicine (Int J Mol Med), Vol. 4 (4): 445-8, 1999 .
Snippet: Differentiation of the papillary variant of papillary thyroid carcinoma (PTC) from papillary hyperplasia in nodular goiter may be difficult in fine-needle aspiration biopsy (FNAB) by means of morphology alone.
Affiliation: Department of Cytopathology, Georg-August University Gottingen, 37075 Gottingen, Germany. .
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13: Title: Association between molecular detection of GAGE and survival in patients with malignant melanoma: a retrospective cohort study.
Authors: Cheung, I Y, et.al. .
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research (Clin Cancer Res), Vol. 5 (8): 2042-7, 1999 .
Snippet: The detection of blood GAGE by reverse transcription-PCR has significant adverse implications for overall survival of patients with malignant melanoma in this cohort, and it warrants further investigation.
Affiliation: Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA. .
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14: Title: Different gene expression of MDM2, GAGE-1, -2 and FHIT in hepatocellular carcinoma and focal nodular hyperplasia.
Authors: Schlott, T, et.al. .
Journal: British journal of cancer (Brit J Cancer), Vol. 80 (1-2): 73-8, 1999 .
Snippet: Cells were analysed for expression and mutation of the oncogene MDM2, the genes GAGE-1, -2 coding for tumour-associated antigens and the candidate tumour suppressor gene FHIT.
Affiliation: Department of Cytopathology, Georg-August-University, Goettingen, Germany. .
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15: Title: Novel genes in the PAGE and GAGE family of tumor antigens found by homology walking in the dbEST database.
Authors: Brinkmann, U, et.al. .
Journal: Cancer research (Cancer Res), Vol. 59 (7): 1445-8, 1999 .
Snippet: XAGE-1 and XAGE-2 are expressed in Ewing's sarcoma, rhabdomyosarcoma, a breast cancer, and a germ cell tumor.
Affiliation: Laboratory of Molecular Biology, Division of Basic Sciences, National Cancer Institute, NIH, Bethesda, Maryland 20892-4255, USA. .
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16: Title: Expression of MAGE and GAGE in high-grade brain tumors: a potential target for specific immunotherapy and diagnostic markers.
Authors: Scarcella, D L, et.al. .
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research (Clin Cancer Res), Vol. 5 (2): 335-41, 1999 .
Snippet: Four groups of tumors--adult glioblastoma multiforme (n = 20), pediatric glioblastoma multiforme (n = 9), medulloblastomas (n = 15), and ependymomas (n = 14)--were analyzed for mRNA expression.
Affiliation: Department of Haematology and Oncology, Royal Children's Hospital, Melbourne, Victoria, Australia. .
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17: Title: MAGE, BAGE and GAGE: tumour antigen expression in benign and malignant ovarian tissue.
Authors: Gillespie, A M, et.al. .
Journal: British journal of cancer (Brit J Cancer), Vol. 78 (6): 816-21, 1998 .
Snippet: In addition, preferential MAGE-1 gene expression in non-malignant premenopausal tissue suggests that the MAGE genes may be involved in cellular proliferation as opposed to carcinogenesis or possibly that MAGE gene expression is under cyclical hormonal control.
Affiliation: Yorkshire Cancer Research Institute for Cancer Studies and Department of Clinical Oncology, University of Sheffield, UK. .
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18: Title: High homogeneity of MAGE, BAGE, GAGE, tyrosinase and Melan-A/MART-1 gene expression in clusters of multiple simultaneous metastases of human melanoma: implications for protocol design of therapeutic antigen-specific vaccination strategies.
Authors: Dalerba, P, et.al. .
Journal: International journal of cancer. Journal international du cancer (Int J Cancer), Vol. 77 (2): 200-4, 1998 .
Snippet: We have studied this issue by assessing, through an RT-PCR approach, the expression of MAGE-1, MAGE-2, MAGE-3, BAGE, GAGE-1/2, Tyrosinase and Melan-A/MART-1 genes in 17 clusters of simultaneous in-transit or regional lymph-node metastases collected from 15 stage-III and 1 stage-IV (AJCC/UICC pTNM system) melanoma patients.
Affiliation: Telethon Institute of Gene Therapy and Gene Therapy Program, Istituto Scientifico H.S. Raffaele, Milan, Italy. .
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19: Title: Expression of the melanoma antigen-encoding gene in human lung cancer.
Authors: Yoshimatsu, T, et.al. .
Journal: Journal of surgical oncology (J Surg Oncol), Vol. 67 (2): 126-9, 1998 .
Snippet: CONCLUSIONS: The high incidence of melanoma antigen-encoding gene expression in lung cancer indicates the possibility of a future specific immunotherapy for this disease.
Affiliation: Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan. .
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20: Title: MAGE BAGE and GAGE genes expression in fresh epithelial ovarian carcinomas.
Authors: Russo, V, et.al. .
Journal: International journal of cancer. Journal international du cancer (Int J Cancer), Vol. 67 (3): 457-60, 1996 .
No Abstract available.
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