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7 documents found
1: Title: Genomic alterations on 8p21-p23 are the most frequent genetic events in stage I squamous cell carcinoma of the lung.
Authors: Kang, Jiun .
Journal: Experimental and therapeutic medicine (Exp Ther Med), Vol. 9 (2): 345-350, 2015 .
Snippet: This region contains the following possible target genes, which have previously not been implicated to play a pathogenic role in stage I SCCs: MSRA, MFHAS1, CLDN23, DEFB106A, DEFB105A, LOC441316, FAM90A7P and LOC441318.
Affiliation: Department of Biomedical Laboratory Science, Korea Nazarene University, Cheonan 330-718, Republic of Korea. .
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2: Title: Unique properties of human β-defensin 6 (hBD6) and glycosaminoglycan complex: sandwich-like dimerization and competition with the chemokine receptor 2 (CCR2) binding site.
Authors: De Paula, Viviane S, et.al. .
Journal: The Journal of biological chemistry (J Biol Chem), Vol. 289 (33): 22969-79, 2014 .
Snippet: Defensins are components of the innate immune system that promote the directional migration and activation of dendritic cells, thereby modulating the adaptive immune response.
Affiliation: From the Centro Nacional de Ressonância Magnética Nuclear de Macromoléculas and Instituto de Bioquímica Médica, Universidade Federal do Rio de Janeiro, Rio de Janeiro RJ 21941-902, Brazil vpaula@cnrmn.bioqmed.ufr.br. Instituto de Bioquímica Médica, Universidade Federal do Rio de Janeiro, Rio de Janeiro RJ 21941-902, Brazil. From the Centro Nacional de Ressonância Magnética Nuclear de Macromoléculas and Instituto de Bioquímica Médica, Universidade Federal do Rio de Janeiro, Rio de Janeiro RJ 21941-902, Brazil valente@cnrmn.bioqmed.ufrj.br. .
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3: Title: Production of bioactive human beta-defensin 5 and 6 in Escherichia coli by soluble fusion expression.
Authors: Huang, Lei, et.al. .
Journal: Protein expression and purification (Protein Expr Purif), Vol. 61 (2): 168-74, 2008 .
Snippet: After cell disruption, the soluble fusion proteins were recovered by affinity chromatography and cleaved by enterokinase.
Affiliation: School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive, Singapore 637459, Singapore. .
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4: Title: Alterations in gene expression in the caput epididymides of nonobstructive azoospermic men.
Authors: Dubé, Evemie, et.al. .
Journal: Biology of reproduction (Biol Reprod), Vol. 78 (2): 342-51, 2008 .
Snippet: Differentially regulated genes included several encoding proteins involved in spermatozoal maturation, water and ion channels, and beta-defensins: CRISP1, SPINLW1, FAM12B, and DEFB129 were upregulated, whereas CFTR, AQP5, KCNK4, KCNK17, SLC6A20, SLC13A3, DEFB126, and DEFB106A were downregulated.
Affiliation: INRS-Institut Armand Frappier, Université du Québec, Laval, Québec, Canada H7V 1B7. .
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5: Title: Human alpha- and beta-defensins block multiple steps in herpes simplex virus infection.
Authors: Hazrati, Ehsan, et.al. .
Journal: Journal of immunology (Baltimore, Md. : 1950) (J Immunol), Vol. 177 (12): 8658-66, 2006 .
Snippet: Surface plasmon resonance studies revealed that HNPs 1, 2, 3, and HD5 bound HSV glycoprotein B (gB) with high affinity, but showed minimal binding to heparan sulfate, the receptor for attachment.
Affiliation: Department of Pediatrics, Mount Sinai School of Medicine, 1 Gustave L. Levy Place, New York, NY 10029, USA. .
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6: Title: Adenovirus-mediated gene therapy enhances parainfluenza virus 3 infection in neonatal lambs.
Authors: Meyerholz, David K, et.al. .
Journal: Journal of clinical microbiology (J Clin Microbiol), Vol. 42 (10): 4780-7, 2004 .
Snippet: The group infected with adenovirus HBD6 and PIV3 had increased levels of pulmonary neutrophil recruitment compared to those for the group infected with PIV3 or PIV3 and adenovirus, with an increased respiration rate and body temperature late in the course of the PIV3-adenovirus HBD6 infection.
Affiliation: Department of Veterinary Pathology, Iowa State University, Ames, Iowa 50011-1250, USA. dmeyerho@iastate.edu .
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7: Title: Identification of multiple novel epididymis-specific beta-defensin isoforms in humans and mice.
Authors: Yamaguchi, Yasuhiro, et.al. .
Journal: Journal of immunology (Baltimore, Md. : 1950) (J Immunol), Vol. 169 (5): 2516-23, 2002 .
Snippet: The epididymis-specific expression pattern of beta-defensin isoform 5 has been characterized.
Affiliation: Division of Integrative Cell Biology, Department of Embryogenesis, Institute of Molecular Embryology and Genetics, Kumamoto University, Japan. .
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