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68 documents found
1: Title: Depletion of death-associated protein-3 induces chemoresistance in gastric cancer cells through the β-catenin/LGR5/Bcl-2 axis.
Authors: Jia, Yongning, et.al. .
Journal: Journal of investigative medicine : the official publication of the American Federation for Clinical Research (J Investig Med), 2019 .
Snippet: However, the protein kinase B , , extracellular regulated protein kinase and signal transducer and activator of transcription 3 signaling pathways remain unaffected by DAP3 loss.
Affiliation: Department of Gastrointestinal Surgery, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China. Department of Gastrointestinal Translational Research, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China. Tissue Bank, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China. .
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2: Title: Matrix replenishing by BMSCs is beneficial for osteoarthritic temporomandibular joint cartilage.
Authors: Zhang, M, et.al. .
Journal: Osteoarthritis and cartilage (Osteoarthritis Cartilage), Vol. 25 (9): 1551-1562, 2017 .
Snippet: Assessments were focused on morphological alterations in UAC mouse TMJ cartilage, the expression levels of DAP3, an anoikis marker, CD163, a scavenger receptor family member, and ki67, a proliferation indicator.
Affiliation: State Key Laboratory of Military Stomatology, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Department of Oral Anatomy and Physiology and TMD, School of Stomatology, The Fourth Military Medical University, 145 Changle West Road, Xi'an, China. Department of Biology, The Fourth Military Medical University, 17 Changle West Road, Xi'an, China. Department of Biology, Shenzhen Key Laboratory of Cell Microenvironment, Southern University of Science and Technology, Shenzhen, China; Department of Biochemistry, Rush University Medical Center, Chicago, IL 60612, USA. State Key Laboratory of Military Stomatology, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Department of Oral Anatomy and Physiology and TMD, School of Stomatology, The Fourth Military Medical University, 145 Changle West Road, Xi'an, China. Electronic address: mqwang@fmmu.edu.cn. .
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3: Title: The intron-enriched HERV-K(HML-10) family suppresses apoptosis, an indicator of malignant transformation.
Authors: Broecker, Felix, et.al. .
Journal: Mobile DNA (Mob Dna), Vol. 7, 2016 .
Snippet: We demonstrated such a regulatory activity for an HML-10 RNA that suppressed DAP3-mediated apoptosis in HeLa cells.
Affiliation: Max Planck Institute for molecular Genetics, Ihnestr. 63-73, 14195 Berlin, Germany ; Institute of Medical Microbiology, University of Zurich, Gloriastr. 32, 8006 Zurich, Switzerland ; Current affiliation: Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, 14424 Potsdam, Germany. Max Planck Institute for molecular Genetics, Ihnestr. 63-73, 14195 Berlin, Germany. Institute of Medical Microbiology, University of Zurich, Gloriastr. 32, 8006 Zurich, Switzerland. Max Planck Institute for molecular Genetics, Ihnestr. 63-73, 14195 Berlin, Germany ; Current affiliation: University of Zurich, Institute of Molecular Life Sciences, Winterthurerstr. 190, 8057 Zurich, Switzerland. Max Planck Institute for molecular Genetics, Ihnestr. 63-73, 14195 Berlin, Germany ; Current affiliation: Functional Epigenomics, CCG, Cologne University Hospital, University of Cologne, Weyertal 115b, 50931 Cologne, Germany. Max Planck Institute for molecular Genetics, Ihnestr. 63-73, 14195 Berlin, Germany ; Dahlem Centre for Genome Research and Medical Systems Biology, Fabeckstr. 60-62, 14195 Berlin, Germany. Max Planck Institute for molecular Genetics, Ihnestr. 63-73, 14195 Berlin, Germany ; Institute of Medical Microbiology, University of Zurich, Gloriastr. 32, 8006 Zurich, Switzerland. .
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4: Title: Triple-layer dissection of the lung adenocarcinoma transcriptome: regulation at the gene, transcript, and exon levels.
Authors: Hsu, Min-Kung, et.al. .
Journal: Oncotarget, Vol. 6 (30): 28755-73, 2015 .
Snippet: Genes selected by both detection methods include C16orf59, DAP3, ETV4, GABARAPL1, PPAR, RADIL, RSPO1, SERTM1, SRPK1, ST6GALNAC6, and TNXB.
Affiliation: Department of Biological Science and Technology, National Chiao-Tung University, Hsinchu, Taiwan. Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan. National Institute of Cancer Research, National Health Research Institutes, Zhunan, Taiwan. Graduate Institute of Cancer Biology, China Medical University, Taichung, Taiwan. Department of Biotechnology, Asia University, Taichung, Taiwan. Center for Molecular Medicine, China Medical University Hospital, Taichung, Taiwan. Cloud Computing and System Integration Division, National Center for High-Performance Computing, Taichung, Taiwan. Department of Dentistry, China Medical University, Taichung, Taiwan. .
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5: Title: Death-associated Protein 3 Regulates Mitochondrial-encoded Protein Synthesis and Mitochondrial Dynamics.
Authors: Xiao, Lin, et.al. .
Journal: The Journal of biological chemistry (J Biol Chem), Vol. 290 (41): 24961-74, 2015 .
Snippet: DAP3 is a mitochondrial ribosomal protein that involves in apoptosis, but its biological function has not been well characterized.
Affiliation: From the Department of Biological Sciences, Faculty of Science, National University of Singapore, 14 Science Drive 4, Singapore 117543. the Neuroscience and Behavioural Disorders Program, Duke-NUS Graduate Medical School, Singapore 169857, the NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore 117573. the NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore 117573, the Temasek Life Sciences Laboratory and Department of Biological Sciences, National University of Singapore, 1 Research Link, Singapore 117604, and. the Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore. From the Department of Biological Sciences, Faculty of Science, National University of Singapore, 14 Science Drive 4, Singapore 117543, the NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore 117573, dbslyc@nus.edu.sg. .
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6: Title: The role of death-associated protein 3 in apoptosis, anoikis and human cancer.
Authors: Wazir, Umar, et.al. .
Journal: Cancer cell international (Cancer Cell Int), Vol. 15, 2015 .
Snippet: Death-associated protein 3 (DAP3) is a molecule with a significant role in the control of both apoptosis and anoikis.
Affiliation: The London Breast Institute, Princess Grace Hospital, London, UK ; Department of Breast Surgery, St. George's Hospital and Medical School, University of London, London, UK. Ayub Medical College, Abbottabad, Pakistan. Metastasis and Angiogenesis Research Group, University Department of Surgery, Cardiff University School of Medicine, Cardiff University, Cardiff, Wales UK. Department of Breast Surgery, St. George's Hospital and Medical School, University of London, London, UK. The London Breast Institute, Princess Grace Hospital, London, UK. .
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7: Title: Effects of the knockdown of death-associated protein 3 expression on cell adhesion, growth and migration in breast cancer cells.
Authors: Wazir, Umar, et.al. .
Journal: Oncology reports (Oncol Rep), Vol. 33 (5): 2575-82, 2015 .
Snippet: The death-associated protein 3 (DAP3) is a highly conserved phosphoprotein involved in the regulation of autophagy.
Affiliation: The London Breast Institute, Princess Grace Hospital, London, UK. Cardiff University-Peking University Cancer Institute (CUPUCI), Cardiff University School of Medicine, Cardiff University, Cardiff, Wales, UK. Peshawar Medical College, Peshawar, Pakistan. Department of Breast Surgery, St. George's Hospital and Medical School, University of London, London, UK. .
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8: Title: Effect of trichostatin A on CNE2 nasopharyngeal carcinoma cells--genome-wide DNA methylation alteration.
Authors: Yang, Xiao-Li, et.al. .
Journal: Asian Pacific journal of cancer prevention : APJCP (Asian Pac J Cancer Prev), Vol. 15 (11): 4663-70, 2014 .
Snippet: Three genes (DAP3, HSPB1 and CLDN) were independently confirmed by quantitative real-time PCR.
Affiliation: Medical Scientific Research Center, Guangxi Medical University, Nanning, China E-mail : Shaoming_lu@163.com. .
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9: Title: Diapause-associated protein3 functions as Cu/Zn superoxide dismutase in the Chinese oak silkworm (Antheraea pernyi).
Authors: Bi, Zhenle, et.al. .
Journal: PloS one, Vol. 9 (3): e90435, 2014 .
Snippet: To identify the SOD activity of DAP3, we constructed a prokaryotic expression vector by inserting the coding region sequence into plasmid pET-28a (+) and obtained the purified rHIS-DAP3 fusion protein by Ni-NTA affinitive column.
Affiliation: College of Life Sciences, Zhejiang Sci-Tech University, Hangzhou, China; Tianjin international Joint Academy of Biomedicine, Tianjin, China. College of Life Sciences, Zhejiang Sci-Tech University, Hangzhou, China. .
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10: Title: Death-associated protein-3, DAP-3, correlates with preoperative chemotherapy effectiveness and prognosis of gastric cancer patients following perioperative chemotherapy and radical gastrectomy.
Authors: Jia, Y, et.al. .
Journal: British journal of cancer (Br J Cancer), Vol. 110 (2): 421-9, 2014 .
Snippet: Knockdown of DAP3 expression promoted cell migration and enhanced resistance to chemotherapy by inhibiting apoptosis.Conclusion:DAP3 is a potential molecular marker for response to preoperative chemotherapy and for predicting prognosis in gastric cancer patients treated with neoadjuvant chemotherapy and gastrectomy.
Affiliation: 1] Cardiff University-Peking University School of Oncology Joint Institute, Cardiff University School of Medicine, Heath Park, Cardiff CF14 4XN, UK [2] Metastasis and Angiogenesis Research Group, Cardiff University School of Medicine, Heath Park, Cardiff CF14 4XN, UK [3] Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery, Peking University Cancer Hospital and Institute, No. 52, Haidian District, Beijing 100142, China. 1] Cardiff University-Peking University School of Oncology Joint Institute, Cardiff University School of Medicine, Heath Park, Cardiff CF14 4XN, UK [2] Metastasis and Angiogenesis Research Group, Cardiff University School of Medicine, Heath Park, Cardiff CF14 4XN, UK. 1] Cardiff University-Peking University School of Oncology Joint Institute, Cardiff University School of Medicine, Heath Park, Cardiff CF14 4XN, UK [2] Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery, Peking University Cancer Hospital and Institute, No. 52, Haidian District, Beijing 100142, China. .
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11: Title: Relevance of signaling molecules for apoptosis induction on influenza A virus replication.
Authors: Iwai, Atsushi, et.al. .
Journal: Biochemical and biophysical research communications (Biochem Biophys Res Commun), Vol. 441 (3): 531-7, 2013 .
Snippet: In the virus infected cells, the functions of various host cellular molecules involved in regulation of induction of apoptosis are modulated by IAV proteins to enable effective virus replication.
Affiliation: Aureo Science Co., Ltd., North 21, West 12, Kita-Ku, Sapporo, Hokkaido 001-0021, Japan. .
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12: Title: Targeted cancer exome sequencing reveals recurrent mutations in myeloproliferative neoplasms.
Authors: Tenedini, E, et.al. .
Journal: Leukemia, Vol. 28 (5): 1052-9, 2014 .
Snippet: Excluding the genes already described in MPN, for 8 genes (SCRIB, MIR662, BARD1, TCF12, FAT4, DAP3, POLG and NRAS), we demonstrated a mutation frequency between 3 and 8%.
Affiliation: 1] Center for Genome Research, University of Modena and Reggio Emilia, Modena, Italy [2] Life Sciences Department, University of Modena and Reggio Emilia, Modena, Italy [3] Center for Regenerative Medicine 'Stefano Ferrari', University of Modena and Reggio Emilia, Modena, Italy. 1] Center for Genome Research, University of Modena and Reggio Emilia, Modena, Italy [2] Life Sciences Department, University of Modena and Reggio Emilia, Modena, Italy. Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy. 1] Life Sciences Department, University of Modena and Reggio Emilia, Modena, Italy [2] Center for Regenerative Medicine 'Stefano Ferrari', University of Modena and Reggio Emilia, Modena, Italy. .
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13: Title: Immunomodulation by different types of N-oxides in the hemocytes of the marine bivalve Mytilus galloprovincialis.
Authors: Ciacci, Caterina, et.al. .
Journal: PloS one, Vol. 7 (5): e36937, 2012 .
Snippet: Hemocyte lysosomal and mitochondrial parameters, oxyradical and nitric oxide production, phagocytic activity, as well as NP uptake, were evaluated.
Affiliation: Dipartimento di Scienze della Terra, della Vita e dell'Ambiente-DISUAN, Università degli Studi di Urbino Carlo Bo, Urbino, Italy. .
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14: Title: The mRNA expression of DAP3 in human breast cancer: correlation with clinicopathological parameters.
Authors: Wazir, U, et.al. .
Journal: Anticancer research (Anticancer Res), Vol. 32 (2): 671-4, 2012 .
Snippet: Lower DAP3 expression levels were significantly associated with local recurrence (p=0.013),
Affiliation: MS FRCS, London Breast Institute, The Princess Grace Hospital, 45 Nottingham Place, London, W1U 5NY, UK. .
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15: Title: Ghrelin modulates physiologic and pathologic retinal angiogenesis through GHSR-1a.
Authors: Zaniolo, Karine, et.al. .
Journal: Investigative ophthalmology & visual science (Invest Ophthalmol Vis Sci), Vol. 52 (8): 5376-86, 2011 .
Snippet: Intravitreal delivery of [Dap3]-ghrelin during OIR significantly reduces retinal vessel loss when administered during the hyperoxic phase.
Affiliation: Department of Pediatrics, Hôpital Sainte-Justine Research Center, Montreal, Quebec, Canada. .
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16: Title: Identification of DELE, a novel DAP3-binding protein which is crucial for death receptor-mediated apoptosis induction.
Authors: Harada, Tanenobu, et.al. .
Journal: Apoptosis : an international journal on programmed cell death (Apoptosis), Vol. 15 (10): 1247-55, 2010 .
Snippet: To understand the molecular mechanism of how DAP3 induces apoptosis, we performed yeast two-hybrid screening, and identified a novel DAP3-binding protein termed death ligand signal enhancer (DELE).
Affiliation: Department of Bioresources, Hokkaido University Research Center for Zoonosis Control, North 20, West 10, Kita-ku, Sapporo, Hokkaido, 001-0020, Japan. .
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17: Title: In vitro and in vivo effect of acylated and unacylated ghrelin on neonatal glucose homeostasis.
Authors: Ni, Hehong, et.al. .
Journal: Pediatric research (Pediatr Res), Vol. 67 (6): 609-13, 2010 .
Snippet: Ghrelin (1-5) amide, [Dap3]-octanoyl, a pentapeptide that is resistant to deacylation and binds the GHSR-1a, had similar effects at 10(-8) M. In vivo, AG, UAG, or GHRP-6 [D-Lys3], a GHSR-1a antagonist, did not affect insulin or glucagon concentrations during the first 3 h of life.
Affiliation: Endocrinology and Diabetes Unit, British Columbia Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada. .
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18: Title: Uncoupling protein-1 is not leaky.
Authors: Shabalina, Irina G, et.al. .
Journal: Biochimica et biophysica acta (Biochim Biophys Acta), Vol. 1797 (6-7): 773-84, 2010 Jun-Jul .
Snippet: Using optimal conditions, we find no evidence for a residual proton conductance (not a higher post-GDP respiration, a lower membrane potential or an altered proton leak at highest common potential) with either pyruvate or glycerol-3-phosphate as substrates, nor by a 3-4-fold alteration of the amount of UCP1.
Affiliation: The Wenner-Gren Institute, Stockholm University, SE-106 91 Stockholm, Sweden. .
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19: Title: Critical function of death-associated protein 3 in T cell receptor-mediated apoptosis induction.
Authors: Tosa, Noriko, et.al. .
Journal: Biochemical and biophysical research communications (Biochem Biophys Res Commun), Vol. 395 (3): 356-60, 2010 .
Snippet: This report demonstrates that DAP3 is also important for T cell receptor (TCR)-mediated apoptosis induction in immature thymocytes.
Affiliation: Institute for Animal Experimentation, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido 060-8638, Japan. .
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20: Title: Gamma-glutamyl 16-diaminopropane derivative of vasoactive intestinal peptide: a potent anti-oxidative agent for human epidermoid cancer cells.
Authors: Stiuso, Paola, et.al. .
Journal: Amino acids, Vol. 39 (3): 661-70, 2010 .
Snippet: Herein, we have evaluated the effects of VIP and gamma-Gln16-diaminopropane derivative of VIP (VIP-DAP3) on the proliferation and protection from oxidative stress induced by hydrogen peroxide (H2O2) on epidermoid carcinoma cell lines.
Affiliation: Department of Biochemistry and Biophysics, Second University of Naples, Via Costantinopoli 16, 80138, Naples, Italy. .
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