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1: Title: Huntington's disease biomarker progression profile identified by transcriptome sequencing in peripheral blood.
Journal: European journal of human genetics : EJHG (Eur J Hum Genet), Vol. 23 (10): 1349-56, 2015 .
Snippet: The five genes (PROK2, ZNF238, AQP9, CYSTM1 and ANXA3) that were validated independently in both cohorts present a candidate biomarker panel for stage determination and therapeutic readout in Huntington's disease.
Affiliation: Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. Leiden Genome Technology Center, Leiden University Medical Center, Leiden, The Netherlands. Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, The Netherlands. Department for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands. Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands. Center for Mental Health Care Delfland, Jorisweg 2, Delft, The Netherlands. Department of Neurology, Leiden University Medical Centre, RC, Leiden, The Netherlands. .
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