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15 documents found
1: Title: Thermodynamics of interactions between mammalian cytochromes P450 and b5.
Authors: Yablokov, Evgeny, et.al. .
Journal: Archives of biochemistry and biophysics (Arch Biochem Biophys), Vol. 619, 2017 .
Snippet: The entropy-driven complexes were formed when CYB5 had no effect on the CYP activity (CYB5A-CYP51A1, CYB5A-CYP1B1, CYB5B-CYP11A1).
Affiliation: Institute of Biomedical Chemistry, Pogodinskaya Str. 10, Bldg 8, Moscow 119121, Russia. Electronic address: evgeyablokov1988@mail.ru. Institute of Biomedical Chemistry, Pogodinskaya Str. 10, Bldg 8, Moscow 119121, Russia. Institute of Bioorganic Chemistry, Kuprevicha Str. 5/2, Minsk 220141, Belarus. .
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2: Title: Elucidating the cancer-specific genetic alteration spectrum of glioblastoma derived cell lines from whole exome and RNA sequencing.
Authors: Patil, Vikas, et.al. .
Journal: Oncotarget, Vol. 6 (41): 43452-71, 2015 .
Snippet: Five significant gene fusions were found of which NUP93-CYB5B was validated.
Affiliation: Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India. .
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3: Title: Gene-smoking interactions identify several novel blood pressure loci in the Framingham Heart Study.
Authors: Sung, Yun J, et.al. .
Journal: American journal of hypertension (Am J Hypertens), Vol. 28 (3): 343-54, 2015 .
Snippet: Identified through the joint 2 df test, significant SBP loci include: rs12149862 (P = 3.65×10(-9)) in CYB5B, rs2268365 (P = 4.85×10(-8)) in LRP2, rs133980 (P = 1.71×10(-8) with CPD and P = 1.07×10(-8) with pack-years) near MN1, and rs12634933 (P = 4.05×10(-8)) in MECOM.
Affiliation: Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri; yunju@wubios.wustl.edu. Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri; Cardiovascular Division, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri. Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri; .
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4: Title: The N-reductive system composed of mitochondrial amidoxime reducing component (mARC), cytochrome b5 (CYB5B) and cytochrome b5 reductase (CYB5R) is regulated by fasting and high fat diet in mice.
Authors: Jakobs, Heyka H, et.al. .
Journal: PloS one, Vol. 9 (8): e105371, 2014 .
Snippet: The protein is capable of reducing N-oxygenated structures, but requires cytochrome b5 and cytochrome b5 reductase for electron transfer to catalyze such reactions.
Affiliation: Department of Pharmaceutical and Medicinal Chemistry, Christian-Albrechts-Universität zu Kiel, Kiel, Germany. Department of Genetics, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland. Department of Genetics, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland; Department of Gastroenterology and Hepatology, Medical Center for Postgraduate Education, Warsaw, Poland. .
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5: Title: The involvement of mitochondrial amidoxime reducing components 1 and 2 and mitochondrial cytochrome b5 in N-reductive metabolism in human cells.
Authors: Plitzko, Birte, et.al. .
Journal: The Journal of biological chemistry (J Biol Chem), Vol. 288 (28): 20228-37, 2013 .
Snippet: Finally, we created recombinant CYB5B variants corresponding to four nonsynonymous single nucleotide polymorphisms (SNPs).
Affiliation: Department of Pharmaceutical and Medicinal Chemistry, Pharmaceutical Institute, Christian-Albrechts-University of Kiel, 24118 Kiel, Germany. .
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6: Title: Pemphigus vulgaris autoantibody profiling by proteomic technique.
Journal: PloS one, Vol. 8 (3): e57587, 2013 .
Snippet: The frequency of antigen recognition by patients that exceeded that of control by 10 and more times were the molecules encoded by the CD33, GP1BA, CHRND, SLC36A4, CD1B, CD32, CDH8, CDH9, PMP22 and HLA-E genes as well as mitochondrial proteins encoded by the NDUFS1, CYB5B, SOD2, PDHA1 and FH genes.
Affiliation: Department of Dermatology, University of California Irvine, Irvine, California, United States of America. mkalanta@uci.edu .
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7: Title: Brain transcriptome-wide screen for HIV-1 Nef protein interaction partners reveals various membrane-associated proteins.
Authors: Kammula, Ellen C, et.al. .
Journal: PloS one, Vol. 7 (12): e51578, 2012 .
Snippet: The identified hits are GPM6B, GPM6A, BAP31, TSPAN7, CYB5B, CD320/TCblR, VSIG4, PMEPA1, OCIAD1, ITGB1, CHN1, PH4, CLDN10, HSPA9, APR-3, PEBP1 and B3GNT, which are involved in diverse cellular processes like signaling, apoptosis, neurogenesis, cell adhesion and protein trafficking or quality control.
Affiliation: Institute of Complex Systems, ICS-6: Structural Biochemistry, Forschungszentrum Jülich, Jülich, Germany. .
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8: Title: Amidoxime reductase system containing cytochrome b5 type B (CYB5B) and MOSC2 is of importance for lipid synthesis in adipocyte mitochondria.
Authors: Neve, Etienne P A, et.al. .
Journal: The Journal of biological chemistry (J Biol Chem), Vol. 287 (9): 6307-17, 2012 .
Snippet: siRNA-mediated down-regulation of MOSC2 and the mitochondrial form of cytochrome b(5) type B (CYB5B) significantly inhibited the reductase activity in the differentiated adipocytes, whereas down-regulation of MOSC1, cytochrome b(5) type A (CYB5A), CYB5R1, CYB5R2, or CYB5R3 had no effect.
Affiliation: Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, SE-17177 Stockholm. .
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9: Title: A micropreparation of mitochondria from cells using magnetic beads with immunoaffinity.
Authors: Ru, Yawei, et.al. .
Journal: Analytical biochemistry (Anal Biochem), Vol. 421 (1): 219-26, 2012 .
Snippet: The polyclonal antibodies against the truncated CYB5B and SYNJ2BP exhibited specific recognition to mitochondria and wider sensitivity to several tested mouse tissues and cell lines, whereas the antibody 22-kDa translocase of the outer mitochondrial membrane (TOM22) nearly missed detection of mitochondria in the liver and responded minimally to mitochondria from H9C2 and L-02 cells.
Affiliation: Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 101318, China. .
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10: Title: Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge.
Authors: James, Rachel, et.al. .
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism (J Cereb Blood Flow Metab), Vol. 32 (1): 164-76, 2012 .
Snippet: A total of 12 mitochondrial proteins (including respiratory chain proteins NDUFA11, NDUFS3, NDUF5B, ATP5J, as well as ETFA, CYB5B, ATP6V1A, HSPA1B, OXR1, GLUL, IARS2, and PHYHIPL) were significantly altered with respect to genotype, global ischemia, or their interaction (P<0.01).
Affiliation: Centre for Cognitive Aging and Cognitive Epidemiology, Centre for Cognitive and Neural Systems, School of Biomedical Sciences, University of Edinburgh, Edinburgh, UK. .
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11: Title: Effect of luteinizing hormone on the steroidogenic pathway in prostate cancer.
Authors: Pinski, Jacek, et.al. .
Journal: The Prostate (Prostate), Vol. 71 (8): 892-8, 2011 .
Snippet: This was mirrored by an increase in the expression of several key steroidogenic enzymes, including StAR, CYB5B, CYP11A, and 3βHSD.
Affiliation: University of Southern California/Norris Comprehensive Cancer Center, Keck School of Medicine, Los Angeles, CA 90033, USA. pinski_j@ccnt.usc.edu .
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12: Title: [Characteristics of gene expression of adrenal cortical steroid synthetase and its regulatory factor in mice with H22 liver cancer of different patterns].
Authors: Pan, Zhi-qiang, et.al. .
Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine / Zhongguo Zhong xi yi jie he xue hui, Zhongguo Zhong yi yan jiu yuan zhu ban (Zhongguo Zhong Xi Yi Jie He Za Zhi), Vol. 31 (1): 85-9, 2011 .
Snippet: However, Cyp11a1 was down-regulated and Cyp1b2 up-regulated in all patterns; Hsd3b1 and Cyp21a1 down-regulated in pattern A and B, but up-regulated in pattern C and D. As for the expressions of the relative regulatory factors, Cyb5b and Wnt4 were down-regulated but Fdx1, Fdxr, Hsd11b1, Por, Agt and Nr 0b1 were up-regulated in all patterns; Nr5al down-regulated in pattern A but up-regulated in other three patterns; Nr4al and Nr4a2 up-regulated in pattern A and down-regulated in the others.
Affiliation: Basic Medical School, Shanghai University of Traditional Chinese Medicine, Shanghai. .
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13: Title: A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16.
Authors: Carelli, Valerio, et.al. .
Journal: Human molecular genetics (Hum Mol Genet), Vol. 20 (10): 1893-905, 2011 .
Snippet: Genomic screening of 45 genes in this interval including several likely candidate genes (CALB2, CYB5B, TK2, DHODH, PLEKHG4) revealed no mutation.
Affiliation: Department of Neurological Sciences, University of Bologna, Via Ugo Foscolo 7, 40123 Bologna, Italy. valerio.carelli@unibo.it .
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14: Title: Constitutively overexpressed 21 kDa protein in Hodgkin lymphoma and aggressive non-Hodgkin lymphomas identified as cytochrome B5b (CYB5B).
Authors: Murphy, Derek, et.al. .
Journal: Molecular cancer (Mol Cancer), Vol. 9, 2010 .
Snippet: RT-PCR assays of RNA extracted from T and B cell enriched fractions obtained from normal peripheral blood mononuclear cells, reactive lymph nodes, tonsils and normal bone marrow samples showed no evidence of increased mRNA levels of CYB5B in comparison to housekeeping gene GAPDH.
Affiliation: Centre for Translational and Applied Genomics, British Columbia Cancer Agency, Provincial Health Services Authority Laboratories, 600 West 10th Avenue, Vancouver, British Columbia, V5Z 4E6, Canada. .
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15: Title: The role of porcine cytochrome b5A and cytochrome b5B in the regulation of cytochrome P45017A1 activities.
Authors: Billen, M J, et.al. .
Journal: The Journal of steroid biochemistry and molecular biology (J Steroid Biochem), Vol. 113 (1-2): 98-104, 2009 .
Snippet: We have expressed CYP17A1, along with cytochrome P450 reductase (POR), cytochrome b5 reductase (CYB5R3) and cytochrome b5 (CYB5) in HEK-293FT cells to investigate the importance of the two forms of porcine CYB5, CYB5A and CYB5B, in both the andien-beta synthase as well as the 17alpha-hydroxylase and C17,20 lyase reactions.
Affiliation: Department of Animal Poultry Science, University of Guelph, Guelph, Ontario, Canada N1G 2W1. .
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