refine search
Authors
Locations
Journals
Publication Dates
Find concepts in Knowledge Base
Explore current query
documentsstatisticstop authorclipboard
6 documents found
1: Title: Association between 5q23.2-located polymorphism of CTXN3 gene (Cortexin 3) and schizophrenia in European-Caucasian males; implications for the aetiology of schizophrenia.
Authors: Šerý, Omar, et.al. .
Journal: Behavioral and brain functions : BBF (Behav Brain Funct), Vol. 11, 2015 .
Snippet: CTXN3 resides in a genomic region (5q21-34) known to be associated with schizophrenia and encodes a protein cortexin 3 which is highly enriched in brain.
Affiliation: Laboratory of Neurobiology and Molecular Psychiatry, Laboratory of Molecular Physiology, Department of Biochemistry, Faculty of Science, Masaryk University, Kotlářská 2, 611 37, Brno, Czech Republic. omarsery@sci.muni.cz. Institute of Animal Physiology and Genetics, Academy of Sciences, Veveří 97, 602 00, Brno, Czech Republic. omarsery@sci.muni.cz. Laboratory of Neurobiology and Molecular Psychiatry, Laboratory of Molecular Physiology, Department of Biochemistry, Faculty of Science, Masaryk University, Kotlářská 2, 611 37, Brno, Czech Republic. 13418@mail.muni.cz. Department of Epidemiology and Public Health, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic. Jana.Povova@osu.cz. Department of Epidemiology and Public Health, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic. Vladimir.Janout@osu.cz. Laboratory of Neurobiology and Molecular Psychiatry, Laboratory of Molecular Physiology, Department of Biochemistry, Faculty of Science, Masaryk University, Kotlářská 2, 611 37, Brno, Czech Republic. 324081@mail.muni.cz. Laboratory of Neurochemistry, Bosch Institute and Discipline of Anatomy and Histology, School of Medical Sciences, Sydney Medical School, The University of Sydney, 2006, Sydney, NSW, AUSTRALIA. vibar@anatomy.usyd.edu.au. .
Related Products: order online
2: Title: A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly.
Authors: Chouraki, V, et.al. .
Journal: Molecular psychiatry (Mol Psychiatry), Vol. 19 (12): 1326-35, 2014 .
Snippet: We also assessed the biological impact of the gene most strongly associated with plasma Aβ1-42 levels (cortexin 3, CTXN3) on APP metabolism in vitro and found that the gene protein was able to modulate Aβ1-42 secretion.
Affiliation: 1] INSERM U744, Lille, France [2] Institut pasteur de Lille, Lille, France [3] Université Lille-Nord de France, Lille, France. 1] Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands [2] Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands [3] Netherlands Consortium for Healthy Aging, Leiden, The Netherlands. Cardiovascular Health Resarch Unit and Department of Medicine, University of Washington, Seattle, WA, USA. 1] The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA [2] The Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA [3] The Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA. 1] Université Lille-Nord de France, Lille, France [2] Inserm U837, Jean-Pierre Aubert Research Centre, Lille, France [3] Centre Hospitalier Régional Universitaire de Lille, Lille, France. 1] Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands [2] Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands. The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA. INSERM U888, Hôpital La Colombière, Montpellier, France. INSERM U593, Victor Segalen University, Bordeaux, France. 1] Netherlands Consortium for Healthy Aging, Leiden, The Netherlands [2] Department of Internal medicine, Leiden, Erasmus MC University Medical Center, Rotterdam, The Netherlands. 1] Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands [2] Netherlands Consortium for Healthy Aging, Leiden, The Netherlands. 1] Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands [2] DZNE, German Center for Neurodegenerative Diseases, Bonn, Germany. Alzheimer's Disease Research Center, Departments of Neurology, Psychiatry and Psychology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. 1] Fondation Jean Dausset-Centre d'Etude du Polymorphisme Humain, Paris, France [2] Centre National de Genotypage, Institut Genomique, Commissariat à l'énergie Atomique, Evry, France. The Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA. INSERM U708, Paris, France. 1] The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA [2] The Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY, USA. 1] INSERM U744, Lille, France [2] Institut pasteur de Lille, Lille, France [3] Université Lille-Nord de France, Lille, France [4] Centre Hospitalier Régional Universitaire de Lille, Lille, France. 1] Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands [2] Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands [3] Netherlands Consortium for Healthy Aging, Leiden, The Netherlands [4] Department of Radiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands. 1] INSERM U593, Victor Segalen University, Bordeaux, France [2] INSERM U708, Paris, France. .
Related Products: order online
3: Title: Association of CTXN3-SLC12A2 polymorphisms and schizophrenia in a Thai population.
Authors: Panichareon, Benjaporn, et.al. .
Journal: Behavioral and brain functions : BBF (Behav Brain Funct), Vol. 8, 2012 .
Snippet: Further study is required for clarification the role of genetic variation around these SNPs in expression pattern of the CTXN3 and SLC12A2 genes, which may be involved in schizophrenia pathogenesis.
Affiliation: Department of Biochemistry, Faculty of Medicine, Srinakharinwirot University, Bangkok, 10110, Thailand. .
Related Products: order online
4: Title: Identifying gene regulatory networks in schizophrenia.
Authors: Potkin, Steven G, et.al. .
Journal: NeuroImage, Vol. 53 (3): 839-47, 2010 .
Snippet: Several of these genes (RSRC1, ARHGAP18, ROBO1-ROBO2, GPC1, TNIK, and CTXN3-SLC12A2) have functions related to progenitor cell proliferation, migration, and differentiation, cytoskeleton reorganization, axonal connectivity, and development of forebrain structures.
Affiliation: Department of Psychiatry & Human Behavior, 5251 California Avenue, Suite 240, University of California, Irvine, CA 92617, USA. sgpotkin@uci.edu .
Related Products: order online
5: Title: A genome-wide association study of schizophrenia using brain activation as a quantitative phenotype.
Authors: Potkin, Steven G, et.al. .
Journal: Schizophrenia bulletin (Schizophrenia Bull), Vol. 35 (1): 96-108, 2009 .
Snippet: RESULTS: Three genes or chromosomal regions were identified by having 2 single-nucleotide polymorphisms (SNPs) each significant at P < 10(-6) for the interaction between the imaging QT and the diagnosis (ROBO1-ROBO2, TNIK, and CTXN3-SLC12A2).
Affiliation: Department of Psychiatry and Human Behavior, University of California, Irvine, CA 92617, USA. sgpotkin@uci.edu .
Related Products: order online
6: Title: In silico-initiated cloning and molecular characterization of cortexin 3, a novel human gene specifically expressed in the kidney and brain, and well conserved in vertebrates.
Authors: Wang, Hai Tao, et.al. .
Journal: International journal of molecular medicine (Int J Mol Med), Vol. 20 (4): 501-10, 2007 .
Snippet: Further analysis of the encoded protein using PSORT II, TMpred, and PSIPRED programs demonstrated a putative single membrane-spanning domain in the middle of the CTXN3 amino acid sequence, indicating that it might be an integral membrane protein which may mediate extracellular or intracellular signaling of the kidney or brain.
Affiliation: Department of Interventional and Minimally Invasive Therapy, Tianjin Cancer Institute and Hospital, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University, 300060 TianJin, P.R. China. peterrock2000@126.com .
Related Products: order online
Documents per page: 20 | 50 | 100