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6 documents found
1: Title: A subset of genetic susceptibility variants for colorectal cancer also has prognostic value.
Authors: Noci, S, et.al. .
Journal: The pharmacogenomics journal (Pharmacogenomics J), Vol. 16 (2): 173-9, 2016 .
Snippet: Two additional SNPs associated with TTR, namely rs16892766 (downstream of EIF3H) and rs10749971 (COLCA2).
Affiliation: Department of Predictive and Preventive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Consortium for Human Molecular Genetics, University of Milano-Bicocca, Monza, Italy. Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Division of General Surgery B, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. .
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2: Title: Enrichment of inflammatory bowel disease and colorectal cancer risk variants in colon expression quantitative trait loci.
Authors: Hulur, Imge, et.al. .
Journal: BMC genomics, Vol. 16, 2015 .
Snippet: The CRC-associated eQTL rs3802842 was associated with the expression of C11orf93 (COLCA2).
Affiliation: Committee on Genetics, Genomics and Systems Biology, Chicago, IL, 60637, USA. imgeh@uchicago.edu. Department of Medicine, 900 East 57th Street, MB#9, Chicago, IL, 60637, USA. egamazon@medicine.bsd.uchicago.edu. Division of Genetic Medicine, Department of Medicine, Vanderbilt University, Nashville, TN, 37232, USA. egamazon@medicine.bsd.uchicago.edu. Department of Medicine, 900 East 57th Street, MB#9, Chicago, IL, 60637, USA. skol@uchicago.edu. Department of Medicine, Yale University, New Haven, CT, 06510, USA. rosa.xicola@yale.edu. Department of Medicine, Yale University, New Haven, CT, 06510, USA. Xavier.llor@yale.edu. Department of Pediatrics, University of Chicago, Chicago, IL, 60637, USA. konel@peds.bsd.uchicago.edu. University of Arizona Cancer Center, Tucson, AZ, 85724, USA. naellis@email.arizona.edu. Department of Medicine, 900 East 57th Street, MB#9, Chicago, IL, 60637, USA. skupfer@medicine.bsd.uchicago.edu. .
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3: Title: Characterization of expression quantitative trait loci in the human colon.
Authors: Singh, Tarjinder, et.al. .
Journal: Inflammatory bowel diseases (Inflamm Bowel Dis), Vol. 21 (2): 251-6, 2015 .
Snippet: A colorectal cancer locus at 11q23 contained a rectal eQTL for COLCA2, a protein implicated in colon cancer pathogenesis.
Affiliation: *Medical Genomics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom; †Division of Medicine, University College London, London, United Kingdom; ‡Department of Gastroenterology, University College London Hospitals NHS Foundation Trust, London, United Kingdom; and §Eastman Dental Institute, University College London, London, United Kingdom. .
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4: Title: Identification of candidate susceptibility genes for colorectal cancer through eQTL analysis.
Authors: Closa, Adria, et.al. .
Journal: Carcinogenesis, Vol. 35 (9): 2039-46, 2014 .
Snippet: We have found Bonferroni-significant cis-eQTLs in three loci: rs3802842 in 11q23.1 associated to C11orf53, COLCA1 (C11orf92) and COLCA2 (C11orf93; r = 0.60); rs7136702 in 12q13.12
Affiliation: Cancer Prevention and Control Program, Catalan Institute of Oncology, and Consortium for Biomedical Research on Epidemiology and Public Health (CIBERESP), Barcelona E08907, Spain, Colorectal Cancer Group, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona E08907, Spain. Gastroenterology Service, Bellvitge University Hospital, Barcelona E08907, Spain and. Department of Clinical Sciences, Faculty of Medicine, University of Barcelona, Barcelona E08907, Spain, General and Digestive Surgery Service, Bellvitge University Hospital, Barcelona E08907, Spain. Medical Oncology Service, Catalan Institute of Oncology, Barcelona E08907, Spain. Cancer Prevention and Control Program, Catalan Institute of Oncology, and Consortium for Biomedical Research on Epidemiology and Public Health (CIBERESP), Barcelona E08907, Spain, Colorectal Cancer Group, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona E08907, Spain, Department of Clinical Sciences, Faculty of Medicine, University of Barcelona, Barcelona E08907, Spain, v.moreno@iconcologia.net. .
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5: Title: Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants.
Authors: Peltekova, Vanya D, et.al. .
Journal: International journal of cancer. Journal international du cancer (Int J Cancer), Vol. 134 (10): 2330-41, 2014 .
Snippet: COLCA2 is present in the cytoplasm of normal epithelial, immune and other cell lineages, as well as tumor cells.
Affiliation: Ontario Institute for Cancer Research, Toronto, ON, M5G 0A3, Canada. .
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6: Title: Genetic association of PLCE1, C11orf92-C11orf93, and NOC3L with colorectal cancer risk in the Han population.
Authors: Duan, Xianglong, et.al. .
Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine (Tumour Biol), Vol. 35 (3): 1813-7, 2014 .
Snippet: In this Han Chinese case-control study, we genotyped 203 CRC cases and 296 controls using Sequenom MassARRAY technology and analyzed their associations with CRC using χ(2) tests, SNPStats software, and SHEsis software.
Affiliation: School of Life Sciences, Northwest University, Xi'an, 710069, China. .
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