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11 documents found
1: Title: CCDC85B promotes non-small cell lung cancer cell proliferation and invasion.
Authors: Feng, Yangyang, .
Journal: Molecular carcinogenesis (Mol Carcinog), Vol. 58 (1): 126-134, 2019 .
Snippet: CCDC85B promoted AKT and GSK3β phosphorylation and upregulated the levels of active β-catenin, Wnt targets c-myc, cyclin D1, and MMP7.
Affiliation: Department of Pathology, First Affiliated Hospital and College of Basic Medical Sciences, China Medical University, Shenyang, China. .
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2: Title: The HSA21 gene EURL/C21ORF91 controls neurogenesis within the cerebral cortex and is implicated in the pathogenesis of Down Syndrome.
Authors: Li, Shan Shan, .
Journal: Scientific reports (Sci Rep), Vol. 6, 2016 .
Snippet: We provide evidence that EURL interacts with the coiled-coil domain-containing protein CCDC85B so as to modulate β-catenin levels in cells.
Affiliation: EMBL Australia, The Australian Regenerative Medicine Institute, Monash University, Clayton, Victoria 3800, Australia. The Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Crawley, Western Australia, 6009, Australia. Department of Life Science, Chung-Ang University, Seoul, Korea. Department of Neurobiology, Yale School of Medicine, New Haven, CT 06510, USA. The Florey Institute of Neuroscience and Mental Health, Parkville, Victoria 3010, Australia. Discipline of Anatomy, School of Medical Sciences, Bosch Institute, The University of Sydney, Sydney, New South Wales, Australia. The Anatomy and Neuroscience Department, University of Melbourne, Parkville, Victoria 3010, Australia. .
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3: Title: DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia.
Authors: Markham, Nicholas O, .
Journal: Molecular biology of the cell (Mol Biol Cell), Vol. 25 (17): 2592-603, 2014 .
Snippet: Moreover, all DIPA family members (Ccdc85a, Ccdc85b/DIPA, and Ccdc85c) interact reciprocally with p120 family members (p120, δ-catenin, p0071, and ARVCF), suggesting significant functional overlap.
Affiliation: Vanderbilt-Ingram Cancer Center, Cancer Biology Department, Vanderbilt University Medical Center, Nashville, TN 37232. Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235. Department of Biochemistry and Molecular Biology, University of Texas MD Anderson Cancer Center, Houston, TX 77030. Epithelial Biology Center, Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232. Vanderbilt-Ingram Cancer Center, Cancer Biology Department, Vanderbilt University Medical Center, Nashville, TN 37232 .
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4: Title: Monoclonal antibodies to DIPA: a novel binding partner of p120-catenin isoform 1.
Authors: Markham, Nicholas O, .
Journal: Hybridoma (2005) (Hybridoma (larchmt)), Vol. 31 (4): 246-54, 2012 .
Snippet: Thus, the p120-DIPA interaction may regulate cell signaling and/or transcriptional events, as has been described previously for β-catenin and the LEF/TCF transcription factor family.
Affiliation: Department of Cancer Biology, Vanderbilt University Medical Center, 2220 Pierce Avenue, Nashville, TN 37232, USA. .
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5: Title: Investigation of the radioprotective efficacy of hesperidin against gamma-radiation induced cellular damage in cultured human peripheral blood lymphocytes.
Authors: Kalpana, K B, .
Journal: Mutation research (Mutat Res-fund Mol M), Vol. 676 (1-2): 54-61, 2009 .
Snippet: Based on the above results, 16.38 microM concentration of HN was fixed as the effective dose to further investigate its radioprotective efficacy which was then carried out by pre-incubating lymphocytes with 16.38 microM concentration of HN, exposing the lymphocytes to different doses (1, 2, 3 and 4 Gy) of radiation and investigating radiation induced genetic damage (MN, dicentric aberration, comet assay, DNA fragmentation assay) and biochemical changes (changes in the level of enzymic and non-enzymic antioxidants, lipid peroxidation).
Affiliation: Department of Biochemistry and Biotechnology, Faculty of Science, Annamalai University, Annamalainagar-608002, Tamil Nadu, India. .
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6: Title: Coiled-coil domain containing 85B suppresses the beta-catenin activity in a p53-dependent manner.
Authors: Iwai, A, .
Journal: Oncogene, Vol. 27 (11): 1520-6, 2008 .
Snippet: Here, we show that human coiled-coil domain containing 85B (CCDC85B) is induced by p53 and regulates beta-catenin activity via interaction with the T-cell factor 4 in the nucleus.
Affiliation: Division of Gastroenterology and Hepatology, Department of Medicine, Kyoto University, Kyoto, Japan. .
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7: Title: DIPA, which can localize to the centrosome, associates with p78/MCRS1/MSP58 and acts as a repressor of gene transcription.
Authors: Du, Xiulian, .
Journal: Experimental and molecular pathology (Exp Mol Pathol), Vol. 81 (3): 184-90, 2006 .
Snippet: Taken together, our results revealed a novel protein complex that plays a role in regulation of gene expression and cell proliferation.
Affiliation: Department of Pathology and Laboratory Medicine, 252 John Morgan Building, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. .
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8: Title: Delta-interacting protein A, a new inhibitory partner of CCAAT/enhancer-binding protein beta, implicated in adipocyte differentiation.
Authors: Bezy, Olivier, .
Journal: The Journal of biological chemistry (J Biol Chem), Vol. 280 (12): 11432-8, 2005 .
Snippet: In an attempt to identify novel proteins that interact with C/EBP beta, we performed a yeast two-hybrid screen with a preadipocyte cDNA library and identified a new co-regulator, delta-interacting protein A (DIPA).
Affiliation: Institute of Signaling, Developmental Biology, and Cancer Research, Centre de Biochimie, UMR 6543 CNRS, Faculté des Sciences, Parc Valrose, 06108 Nice cedex 2, France. .
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9: Title: Delta-interacting protein A and the origin of hepatitis delta antigen.
Authors: Long, M, .
Journal: Science (New York, N.Y.) (Science), Vol. 276 (5313): 824-5, 1997 .
No Abstract available.
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10: Title: How did replicating and coding RNAs first get together?
Journal: Science (New York, N.Y.) (Science), Vol. 274 (5284): 66-7, 1996 .
No Abstract available.
Affiliation: Department of Biochemistry, New York Hospital-Cornell Medical Center, New York, New York 10021, USA. .
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11: Title: A cellular homolog of hepatitis delta antigen: implications for viral replication and evolution.
Authors: Brazas, R, .
Journal: Science (New York, N.Y.) (Science), Vol. 274 (5284): 90-4, 1996 .
Snippet: However, viroid genomes contain no open reading frames, whereas HDV RNA encodes a single protein, hepatitis delta antigen (HDAg), which is required for viral replication.
Affiliation: Department of Microbiology, University of California, San Francisco, CA 94143, USA. .
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