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8 documents found
1: Title: Suppressed microRNA-96 inhibits iNOS expression and dopaminergic neuron apoptosis through inactivating the MAPK signaling pathway by targeting CACNG5 in mice with Parkinson's disease.
Authors: Dong, Yue, et.al. .
Journal: Molecular medicine (Cambridge, Mass.) (Mol Med), Vol. 24 (1): 61, 2018 .
Snippet: CONCLUSION: The above results implicated that the downregulation of miR-96 inhibits the activation of iNOS and apoptosis of dopaminergic neuron through the blockade of the MAPK signaling pathway by promoting CACNG5 in mice with PD.
Affiliation: Department of Neurology , China-Japan Union Hospital, Jilin University, No. 126, Xiantai Street, Erdao District, Changchun, 130012, Jilin Province, People's Republic of China. Department of Neurology, Cangzhou Central Hospital, Cangzhou, 061000, People's Republic of China. Department of Neurology , China-Japan Union Hospital, Jilin University, No. 126, Xiantai Street, Erdao District, Changchun, 130012, Jilin Province, People's Republic of China. xzxxuzhongxin@126.com. .
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2: Title: LncRNA LINC00880 promotes cell proliferation, migration and invasion while inhibiting apoptosis by targeting CACNG5 through the MAPK signaling pathway in spinal cord ependymoma.
Authors: Wu, Dong-Mei, et.al. .
Journal: Journal of cellular physiology (J Cell Physiol), 2017 .
Snippet: The present study was to investigate the effect of lncRNA LINC00880 targeting CACNG5 on cell proliferation, migration, invasion and apoptosis in spinal cord ependymoma (SCE) through the MAPK signaling pathway.
Affiliation: Key Laboratory for Biotechnology on Medicinal Plants of Jiangsu Province, School of Life Science, Jiangsu Normal University, Xuzhou 221116, P.R. China. School of Environment Science and Spatial Informatics, China University of Mining and Technology, Xuzhou 221008, P.R. China. Jiangsu Key Laboratory for Eco-Agricultural Biotechnology around Hongze Lake, School of Life Sciences, Huaiyin Normal University, Huaian 223300, P.R. China. .
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3: Title: Evaluation of voltage-dependent calcium channel γ gene families identified several novel potential susceptible genes to schizophrenia.
Authors: Guan, Fanglin, et.al. .
Journal: Scientific reports (Sci Rep), Vol. 6, 2016 .
Snippet: The statistical epistasis identified between CACNG5 and CACNG6 suggests that there may be an underlying biological interaction between the two genes.
Affiliation: Department of Forensic Psychiatry, School of Medicine &Forensics, Xi'an Jiaotong University, Xi'an, China. Key Laboratory of National Ministry of Health for Forensic Sciences, School of Medicine &Forensics, Xi'an Jiaotong University, Xi'an, China. Department of Psychiatry, School of Medicine, Washington University, Saint Louis, MO, USA. Department of Forensic Medicine, School of Medicine &Forensics, Xi'an Jiaotong University, Xi'an, China. Xi'an Mental Health Center, Xi'an, China. .
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4: Title: Differential Gene Expression in Gonadotropin-Releasing Hormone Neurons of Male and Metestrous Female Mice.
Authors: Vastagh, Csaba, et.al. .
Journal: Neuroendocrinology, Vol. 102 (1-2): 44-59, 2015 .
Snippet: We found significant differences in the expression of genes involved in vesicle priming and docking (Syt1, Cplx1), GABAergic (Gabra3, Gabrb3, Gabrg2) and glutamatergic (Gria1, Grin1, Slc17a6) neurotransmission, peptide signaling (Sstr3, Npr2, Cxcr4) and the regulation of intracellular ion homeostasis (Cacna1, Cacnb1, Cacng5, Kcnq2, Kcnc1).
Affiliation: Laboratory of Endocrine Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary. .
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5: Title: Hippocampal CA3 and CA2 have distinct bilateral innervation patterns to CA1 in rodents.
Authors: Shinohara, Yoshiaki, et.al. .
Journal: The European journal of neuroscience (Eur J Neurosci), Vol. 35 (5): 702-10, 2012 .
Snippet: The preferred projection of CA2 pyramidal cells to the CA1 stratum oriens was also manifested in transgenic mice that express GFP under the control of the CACNG5 promoter, in which CA2 cells express high amounts of GFP.
Affiliation: Laboratory for Neuron Glia Circuit, RIKEN Brain Science Institute, Hirosawa 2-1, Wako, Saitama 351-0198, Japan. .
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6: Title: Case-case genome-wide association analysis shows markers differentially associated with schizophrenia and bipolar disorder and implicates calcium channel genes.
Authors: Curtis, David, et.al. .
Journal: Psychiatric genetics (Psychiatr Genet), Vol. 21 (1): 1-4, 2011 .
Snippet: The finding for CACNG5, taken together with the earlier implication of CACNA1C and CACNA1B, strongly suggests a key role for voltage-dependent calcium channel genes in the susceptibility to bipolar disorder and/or schizophrenia.
Affiliation: Centre for Psychiatry, Barts and the London School of Medicine and Dentistry, London, UK. david.curtis@qmul.ac.uk .
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7: Title: A cluster of three novel Ca2+ channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family.
Authors: Burgess, D L, et.al. .
Journal: Genomics, Vol. 71 (3): 339-50, 2001 .
Snippet: The existence of an extended family of gamma subunits was subsequently demonstrated upon identification of CACNG2 (22q13), CACNG3 (16p12-p13), and CACNG4 and CACNG5 (17q24).
Affiliation: Department of Neurology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA. dburgess@bcm.tmc.edu .
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8: Title: Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication.
Authors: Burgess, D L, et.al. .
Journal: Genome research (Genome Res), Vol. 9 (12): 1204-13, 1999 .
Snippet: Low-stringency genomic sequence analysis of targeted regions led to the identification of three novel Ca(2+) channel gamma subunit genes, CACNG3, CACNG4, and CACNG5, on chromosomes 16 and 17.
Affiliation: Department of Neurology, Baylor College of Medicine, Houston, Texas 77030, USA. dburgess@bcm.tmc.edu .
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