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35 documents found
1: Title: Effects of Caloric Restriction with Protein Supplementation on Plasma Protein Profiles in Middle-Aged Women with Metabolic Syndrome-A Preliminary Open Study.
Authors: Chang, Chia-Yu, et.al. .
Journal: Journal of clinical medicine (J Clin Med), Vol. 8 (2), 2019 .
Snippet: After liquid chromatography⁻tandem mass spectrometry analysis, the relative plasma levels of alpha-2-macroglobulin (A2M), C4b-binding protein alpha chain (C4BPA), complement C1r subcomponent-like protein (C1RL), complement component C6 (C6), complement component C8 gamma chain (C8G), and vitamin K-dependent protein S (PROS) were significantly different between the CRPS and CR groups.
Affiliation: School of Nutrition and Health Sciences, Taipei Medical University, Taipei 110, Taiwan. julia21808@gmail.com. Graduate Institute of Metabolism and Obesity Sciences, Taipei Medical University, Taipei 110, Taiwan. f91625059@tmu.edu.tw. Biostatistics Center, Taipei Medical University, Taipei 110, Taiwan. robbinlin@tmu.edu.tw. Proteomics Research Center, National Yang-Ming University, Taipei 112, Taiwan. ccliao@ym.edu.tw. Graduate Institute of Metabolism and Obesity Sciences, Taipei Medical University, Taipei 110, Taiwan. chiucf@tmu.edu.tw. School of Nutrition and Health Sciences, Taipei Medical University, Taipei 110, Taiwan. derossi83621@gmail.com. School of Nutrition and Health Sciences, Taipei Medical University, Taipei 110, Taiwan. amalina.shabrina@yahoo.com. School of Nutrition and Health Sciences, Taipei Medical University, Taipei 110, Taiwan. sihuang@tmu.edu.tw. Graduate Institute of Metabolism and Obesity Sciences, Taipei Medical University, Taipei 110, Taiwan. sihuang@tmu.edu.tw. Center for Reproductive Medicine & Sciences, Taipei Medical University Hospital, Taipei 110, Taiwan. sihuang@tmu.edu.tw. .
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2: Title: iTRAQ-Based Quantitative Proteomics Analysis of the Protective Effect of Yinchenwuling Powder on Hyperlipidemic Rats.
Authors: Zhang, Zheyu, et.al. .
Journal: Evidence-based complementary and alternative medicine : eCAM (Evid Based Complement Alternat Med), Vol. 2017, 2017 .
Snippet: Of these proteins, 2 (Adipoq and Gsta1) were upregulated and 13 (C3, C4, C6, Cfh, Cfp, C8g, C8b, Lgals1, Fndc1, Fgb, Fgg, Kng1, and ApoH) were downregulated in the YCL-treated rats.
Affiliation: Institute of Integrated Traditional Chinese and Western Medicine, Xiangya Hospital, Central South University, Changsha 410008, China. .
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3: Title: Genetic association between inflammatory genes (IL-1α, CD14, LGALS2, PSMA6) and risk of ischemic stroke: A meta-analysis.
Authors: Misra, Shubham, et.al. .
Journal: Meta gene (Unknown Journal), Vol. 8, 2016 .
Snippet: OBJECTIVE: The present meta-analysis aimed to provide a comprehensive account of the association between IL-1α (-C889T and -C511T), CD14 (-C159T), LGALS2 (-C3279T) and PSMA6 (-C8G) gene polymorphisms and susceptibility to IS. METHODS: A literature search for eligible genetic studies published before August 31, 2015 was conducted in the PubMed, Medline, EMBASE, OVID, and Google Scholar databases.
Affiliation: Department of Neurology, All India Institute of Medical Sciences, New Delhi, India. .
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4: Title: The complement system of elasmobranches revealed by liver transcriptome analysis of a hammerhead shark, Sphyrna zygaena.
Authors: Goshima, Masayuki, et.al. .
Journal: Developmental and comparative immunology (Dev Comp Immunol), Vol. 61, 2016 .
Snippet: Identified genes were; one C1qB, one C1r, one C1s, one MASP-1/-3, one MASP-2, two factor B/C2, one C3, three C4, one C5, one C6, one C7, one C8A, three C8B, one C8G, one C9, two factor I and one S protein.
Affiliation: Graduate School of Science and Technology, Tokai University, Japan. Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Japan. Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Japan. Electronic address: mnonaka@bs.s.u-tokyo.ac.jp. .
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5: Title: The three-way relationship of polymorphisms of porcine genes encoding terminal complement components, their differential expression, and health-related phenotypes.
Authors: Wimmers, Klaus, et.al. .
Journal: BMC proceedings (Bmc Proc), Vol. 5 Suppl 4, 2011 .
Snippet: The terminal complement components (TCCs: C6, C7, C8A, C8B, and C9) are encoded by the genes C6, C7, C8A, C8B, C8G, and C9.
Affiliation: Leibniz Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany. wimmers@fbn-dummerstorf.de. .
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6: Title: Protein profiling underscores immunological functions of uterine cervical mucus plug in human pregnancy.
Authors: Lee, Deug-Chan, et.al. .
Journal: Journal of proteomics (J Proteomics), Vol. 74 (6): 817-28, 2011 .
Snippet: Out of 291 total proteins identified, 137 were detected in two or more samples, which included S100A8, S100A9, and complement proteins (C3, C4a, C4b, C6, and C8g).
Affiliation: Perinatology Research Branch, NICHD/NIH/DHHS, Bethesda, Maryland, and Detroit, MI, USA. .
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7: Title: Coding polymorphisms in the genes of the alternative complement pathway and abdominal aortic aneurysm.
Authors: Bradley, D T, et.al. .
Journal: International journal of immunogenetics (Int J Immunogenet), Vol. 38 (3): 243-8, 2011 .
Snippet: This study tested 49 single nucleotide polymorphisms, including common putatively functional polymorphisms, in the genes of the alternative complement cascade (CFH, CFB, CFD, CFI, properdin, CR1, CR1L, CR2, CD46, vitronectin, C3, C5, C6, C7, C8A, C8B, C8G and C9).
Affiliation: Centre for Public Health, Institute of Clinical Sciences, Queen's University Belfast, Royal Victoria Hospital, Grosvenor Road, Belfast, UK. dbradley09@qub.ac.uk .
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8: Title: Serum proteomic analysis of diet-induced steatohepatitis and metabolic syndrome in the Ossabaw miniature swine.
Authors: Bell, Lauren N, et.al. .
Journal: American journal of physiology. Gastrointestinal and liver physiology (Am J Physiol Gastrointest Liver Physiol), Vol. 298 (5): G746-54, 2010 .
Snippet: Biological classification of proteins with significant changes revealed functions previously implicated in development of NASH in humans, including immune system regulation and inflammation (orosomucoid 1, serum amyloid P component, paraoxonase 1, protein similar to alpha-2-macroglobulin precursor, beta-2-microglobulin, p101 protein, and complement components 2 and C8G), lipid metabolism (apolipoproteins C-III, E, E precursor, B, and N), structural and extracellular matrix proteins (transthyretin and endopeptidase 24.16 type M2), and coagulation [carboxypeptidase B2 (plasma)].
Affiliation: Indiana Univ. School of Medicine, Indianapolis, 46202, USA. .
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9: Title: Preparation and characterization of monoclonal antibodies against a polysaccharide from Flammulina velutipes mycelium.
Authors: Zhou, Xuelin, et.al. .
Journal: Hybridoma (2005) (Hybridoma (larchmt)), Vol. 27 (6): 439-44, 2008 .
Snippet: As a result, three hybridoma cell lines named B11D, C8G, and I6D were acquired, and the immunological characteristics of the MAbs were determined.
Affiliation: School of Life Science and Technology, China Pharmaceutical University, Nanjing, P.R. China. .
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10: Title: A disulfide linked model of the complement protein C8gamma complexed with C8alpha indel peptide.
Journal: Journal of molecular modeling (J Mol Model), Vol. 15 (2): 165-71, 2009 .
Snippet: Computer modeling and molecular dynamics simulations were performed in order to check the hypothesis that the residues Ala164 of C8alpha and Ala40 of C8gamma occupied the right position if cysteine residues were in their place for disulfide bonding.
Affiliation: Department of Economics, University of Ioannina, 45110 Ioannina, Greece. astavrak@cc.uoi.gr .
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11: Title: Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit.
Authors: Slade, Daniel J, et.al. .
Journal: Journal of molecular biology (J Mol Biol), Vol. 379 (2): 331-42, 2008 .
Snippet: Human C8 is one of five complement components (C5b, C6, C7, C8, and C9) that assemble on bacterial membranes to form a porelike structure referred to as the "membrane attack complex" (MAC).
Affiliation: Department of Chemistry and Biochemistry, University of South Carolina, Columbia, SC 29208, USA. .
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12: Title: Identification of gene markers for formaldehyde exposure in humans.
Authors: Li, Guang-Yong, et.al. .
Journal: Environmental health perspectives (Environ Health Persp), Vol. 115 (10): 1460-6, 2007 .
Snippet: OBJECTIVES: Our aim was to profile global gene expression in Hs 680.Tr human tracheal fibroblasts exposed to FA and to develop biomarkers for the evaluation of FA exposure in humans.
Affiliation: College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea. .
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13: Title: Crystal structure of complement protein C8gamma in complex with a peptide containing the C8gamma binding site on C8alpha: implications for C8gamma ligand binding.
Authors: Lovelace, Leslie L, et.al. .
Journal: Molecular immunology (Mol Immunol), Vol. 45 (3): 750-6, 2008 .
Snippet: The C8alpha subunit is homologous to C8beta, C6, C7 and C9 and together they form the MAC family of proteins.
Affiliation: Department of Chemistry and Biochemistry and School of Medicine, University of South Carolina, Columbia, SC 29208, United States. .
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14: Title: Structural features of the ligand binding site on human complement protein C8gamma: a member of the lipocalin family.
Authors: Chiswell, Brian, et.al. .
Journal: Biochimica et biophysica acta (Biochim Biophys Acta), Vol. 1774 (5): 637-44, 2007 .
Snippet: Human C8 is one of five components of the cytolytic membrane attack complex of complement.
Affiliation: Department of Chemistry and Biochemistry and School of Medicine, University of South Carolina, Columbia, SC 29208, USA. .
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15: Title: Binding of the lipocalin C8gamma to human complement protein C8alpha is mediated by loops located at the entrance to the C8gamma ligand binding site.
Authors: Chiswell, Brian, et.al. .
Journal: Biochimica et biophysica acta (Biochim Biophys Acta), Vol. 1764 (9): 1518-24, 2006 .
Snippet: Human C8 is one of five complement components (C5b, C6, C7, C8 and C9) that interact to form the membrane attack complex (MAC).
Affiliation: Department of Chemistry and Biochemistry and School of Medicine, University of South Carolina, Columbia, 29208, USA. .
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16: Title: Mixed micelles of series of monomeric and dimeric cationic, zwitterionic, and unequal twin-tail cationic surfactants with sugar surfactants: a fluorescence study.
Authors: Bakshi, Mandeep Singh, et.al. .
Journal: Journal of colloid and interface science (J Colloid Interf Sci), Vol. 289 (2): 551-9, 2005 .
Snippet: Steady state fluorescence measurements have been carried out for binary mixtures of a series of monomeric cationic (MC), zwitterionic (ZI), dimeric cationic (DC), and twin-tail cationic (TC) surfactants with sugar (beta-C8G and beta-C12G) over the whole mole fraction range using pyrene as fluorescence probe.
Affiliation: Department of Chemistry, Guru Nanak Dev University, Amritsar 143005, Punjab, India. ms_bakshi@yahoo.com .
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17: Title: Interaction between the C8 alpha-gamma and C8 beta subunits of human complement C8: role of the C8 beta N-terminal thrombospondin type 1 module and membrane attack complex/perforin domain.
Authors: Musingarimi, Primrose, et.al. .
Journal: Biochemistry (Biochemistry-us), Vol. 41 (37): 11255-60, 2002 .
Snippet: The binding specificity between C8 alpha and C8 beta subunits is determined by a cooperative interaction of the N-terminal thrombospondin type 1 module and the membrane attack complex/perforin domain.
Affiliation: Department of Chemistry and Biochemistry and School of Medicine, University of South Carolina, Columbia, South Carolina 29208, USA. .
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18: Title: Crystal structure of human complement protein C8gamma at 1.2 A resolution reveals a lipocalin fold and a distinct ligand binding site.
Authors: Ortlund, Eric, et.al. .
Journal: Biochemistry (Biochemistry-us), Vol. 41 (22): 7030-7, 2002 .
Snippet: When compared to other lipocalins, the overall structure is most similar to neutrophil gelatinase associated lipocalin (NGAL), a protein released from granules of activated neutrophils.
Affiliation: Department of Chemistry and Biochemistry and the School of Medicine, University of South Carolina, Columbia, South Carolina 29208, USA. .
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19: Title: Hepatocyte nuclear factor 1alpha controls the expression of terminal complement genes.
Authors: Pontoglio, M, et.al. .
Journal: The Journal of experimental medicine (J Exp Med), Vol. 194 (11): 1683-9, 2001 .
Snippet: In this study we show that mice lacking the hepatic transcription factor hepatocyte nuclear factor 1alpha (HNF1alpha) fail to transcribe C5 and C8A complement genes.
Affiliation: Unité des Virus Oncogènes, Centre National de la Recherche Scientifique URA 1644, Département de Biotechnologie, Institut Pasteur, 75724 Paris cedex 15, France. marcop@pasteur.fr .
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20: Title: Lipocalins as biochemical markers of disease.
Authors: Xu, S, et.al. .
Journal: Biochimica et biophysica acta (Biochim Biophys Acta), Vol. 1482 (1-2): 298-307, 2000 .
Snippet: Emphasis, however, will be put on the description of another newly described lipocalin, i.e. human neutrophil lipocalin/neutrophil gelatinase-associated lipocalin (HNL/NGAL), since the body fluid measurement of HNL/NGAL was shown to be a superior means to distinguish between acute viral and bacterial infections and also to accurately reflect the activity and involvement of neutrophils in a variety of other diseases.
Affiliation: Department of Medical Sciences, Clinical Chemistry, University of Uppsala, S-751 85 Uppsala, Sweden. shengyuan.xu@medsci.uu.se .
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