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5 documents found
1: Title: Alex3 suppresses non-small cell lung cancer invasion via AKT/Slug/E-cadherin pathway.
Authors: Du, Jiang, et.al. .
Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine (Tumour Biol), Vol. 39 (7): 1010428317701441, 2017 .
Snippet: After overexpression of Alex3, levels of p-AKT and Slug were downregulated, while level of E-cadherin was upregulated, which results in the inhibition of invasion and migration ability of lung cancer cells.
Affiliation: Department of Pathology, The First Affiliated Hospital and College of Basic Medical Sciences, China Medical University, Shenyang, China. .
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2: Title: Function of Armcx3 and Armc10/SVH Genes in the Regulation of Progenitor Proliferation and Neural Differentiation in the Chicken Spinal Cord.
Authors: Mirra, Serena, et.al. .
Journal: Frontiers in cellular neuroscience (Unknown Journal), Vol. 10, 2016 .
Snippet: Armcx3 and Armc10/SVH are characterized by high expression in the central nervous system and they play an important role in the regulation of mitochondrial distribution and transport in neurons.
Affiliation: Department of Cell Biology, Faculty of Biology, University of BarcelonaBarcelona, Spain; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas, Instituto de Salud Carlos IIIMadrid, Spain. Instituto de Biología Molecular de Barcelona, Consejo Superior de Investigaciones Científicas, ParcCientífic de Barcelona Barcelona, Spain. Department of Cell Biology, Faculty of Biology, University of BarcelonaBarcelona, Spain; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas, Instituto de Salud Carlos IIIMadrid, Spain; Valld'Hebron Institute of ResearchBarcelona, Spain; Institució Catalana de Recerca i Estudis AvançatsBarcelona, Spain. .
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3: Title: The non-canonical Wnt/PKC pathway regulates mitochondrial dynamics through degradation of the arm-like domain-containing protein Alex3.
Authors: Serrat, Román, et.al. .
Journal: PloS one, Vol. 8 (7): e67773, 2013 .
Snippet: The Armcx3 gene encodes a mitochondrial-targeted protein (Alex3) that contains several arm-like domains.
Affiliation: Department of Cell Biology, University of Barcelona, Barcelona, Spain. .
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4: Title: The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2.
Journal: Nature communications (Nat Commun), Vol. 3, 2012 .
Snippet: Furthermore, we demonstrate that Armcx3 expression levels regulate mitochondrial dynamics and trafficking in neurons, and that Alex3 interacts with the Kinesin/Miro/Trak2 complex in a Ca(2+)-dependent manner.
Affiliation: Developmental Neurobiology and Regeneration Lab, IRB Barcelona, Parc Cientific de Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED, ISCIII), Department of Cell Biology, University of Barcelona, Barcelona E-08028, Spain. .
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5: Title: The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10.
Authors: Mou, Zhongming, et.al. .
Journal: The Journal of biological chemistry (J Biol Chem), Vol. 284 (20): 13629-40, 2009 .
Snippet: In addition, although ARMCX3 does not possess intrinsic transcriptional activity, it does enhance transactivation of the nicotinic acetylcholine receptor alpha3 and beta4 subunit gene promoters by Sox10.
Affiliation: Brudnick Neuropsychiatric Research Institute, Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts 01604, USA. .
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