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7 documents found
1: Title: ANKRD49 inhibits etoposide-induced intrinsic apoptosis of GC-1 cells by modulating NF-κB signaling.
Authors: Zhou, Xia, et.al. .
Journal: Molecular and cellular biochemistry (Mol Cell Biochem), 2019 .
Snippet: Nuclear staining with Hoechst 33258 and annexin V-FITC/PI, as well as analysis of caspase 3 activity, mitochondrial membrane potential, and apoptotic protein expression, showed that etoposide-induced apoptosis was attenuated by ANKRD49 overexpression but promoted by RNA interference-induced ANKRD49 knockdown.
Affiliation: School of Basic Medicine, Shanxi Medical University, 030001, Taiyuan, Shanxi, China. School of Basic Medicine, Shanxi Medical University, 030001, Taiyuan, Shanxi, China. longwty@163.com. .
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2: Title: Transcriptome analysis provides insights into differentially expressed genes and long noncoding RNAs involved in sex-related differences in Amur sturgeon (Acipenser schrenckii).
Authors: Zhang, Xin, et.al. .
Journal: Molecular reproduction and development (Mol Reprod Dev), Vol. 86 (2): 132-144, 2019 .
Snippet: Moreover, several lncRNAs targeting Mea1, Piwil1, Tdrd1, Nanos2, Ankrd49, and ZP3 may have potential regulatory effect related to gametogenesis and gonadal differentiation were identified and validated by qRT-PCR.
Affiliation: Department of Aquaculture, College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou, China. Department of Aquaculture, Putian Municipal Institute of Fisheries Research, Putian, China. Department of Aquaculture, Fisheries College, Jimei University, Xiamen, China. .
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3: Title: High expression of the ANKRD49 protein is associated with progression and poor prognosis of gastric cancer.
Authors: Liu, Chen-Guang, et.al. .
Journal: Cancer biomarkers : section A of Disease markers (Cancer Biomark), Vol. 22 (4): 649-656, 2018 .
Snippet: RESULTS: The results revealed that the expression level of the ANKRD49 protein in gastric cancer was significantly upregulated and correlated with the tumour size, tumour-node-metastasis (TNM) stage, histological grade, depth of invasion, vessel invasion, lymph node metastasis and distant metastasis.
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4: Title: Up-regulation of ANKDR49, a poor prognostic factor, regulates cell proliferation of gliomas.
Authors: Hao, Chunyan, et.al. .
Journal: Bioscience reports (Biosci Rep), Vol. 37 (4), 2017 .
Snippet: ANKRD49 knockdown also changed the expression of key effectors that are involved in stress response, cell cycle, and apoptosis, including p-HSP27 (heat shock protein 27), p-Smad2 (SMAD family member 2), p-p53, p-p38, p-MAPK (mitogen-activated protein kinase), p-SAPK/JNK (stress-activated protein kinase/c-jun n-terminal kinase), cleveagated Caspase-7, p-Chk1 (checkpoint kinase 1), and p-eIF2a (eukaryotic translation initiation factor 2a). Taken together, our findings implicate that ANKRD49 promotes the proliferation of human malignant glioma cells.
Affiliation: Department of Geriatrics, First Clinical Medical College of Shanxi Medical University, 85 Jie Fang South Road, Taiyuan 030001, Shanxi Province, People's Republic of China. Department of Neurosurgery, First Clinical Medical College of Shanxi Medical University, 85 Jie Fang South Road, Taiyuan 030001, Shanxi Province, People's Republic of China duanhubin68@126.com. Department of Neurosurgery, First Clinical Medical College of Shanxi Medical University, 85 Jie Fang South Road, Taiyuan 030001, Shanxi Province, People's Republic of China. .
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5: Title: The Ankyrin Repeat Domain 49 (ANKRD49) Augments Autophagy of Serum-Starved GC-1 Cells through the NF-κB Pathway.
Authors: Wang, Hai-long, et.al. .
Journal: PloS one, Vol. 10 (6): e0128551, 2015 .
Snippet: Inhibition of NF-κB pathway by its inhibitors or p65 siRNA prevents the ANKRD49-dependent autophagy augmentation, demonstrating that ANKRD49 enhances autophagy via NF-κB pathway.
Affiliation: Department of Biochemistry and Molecular Biology, Shanxi Medical University, Taiyuan, Shanxi, 030001, PR China. Department of Respiratory, the First Affiliated Hospital, Shanxi Medical University, Taiyuan, Shanxi, 030001, PR China. Class 041002, Department of Anestesioloy, Shanxi Medical University, Taiyuan, Shanxi, 030001, PR China. Center of Laboratory Animal, Shanxi Medical University, Taiyuan, Shanxi, 030001, PR China. State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Peking Union Medical College, Tsinghua University, 5 Dong Dan San Tiao, Beijing, 100005, China. .
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6: Title: Molecular profiling of the lateral habenula in a rat model of depression.
Authors: Christensen, Trine, et.al. .
Journal: PloS one, Vol. 8 (12): e80666, 2013 .
Snippet: Real-time quantitative polymerase chain reaction (RT-PCR) was used to verify the microarray results and determine the expression of the Fcrla, Eif3k, Sec3l1, Ubr5, Abca8a, Ankrd49, Cyp2j10, Frs3, Syn2, and Znf503 genes in the lateral habenula tissue.
Affiliation: Translational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, Risskov, Denmark. .
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7: Title: A four-gene signature from NCI-60 cell line for survival prediction in non-small cell lung cancer.
Authors: Hsu, Yi-Chiung, et.al. .
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research (Clin Cancer Res), Vol. 15 (23): 7309-15, 2009 .
Snippet: RESULTS: The invasion-associated four-gene signature (ANKRD49, LPHN1, RABAC1, and EGLN2) had significant prediction in three validation cohorts (P = 0.0184, 0.002, and 0.017, log-rank test).
Affiliation: Institute of Statistical Science, Academia Sinica, Taipei, Taiwan, Republic of China. .
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