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9 documents found
1: Title: A novel 12-marker panel of cancer-associated fibroblasts involved in progression of hepatocellular carcinoma.
Authors: Zou, Baojia, et.al. .
Journal: Cancer management and research (Cancer Manag Res), Vol. 10, 2018 .
Snippet: Results: We successfully identified 12 CAF markers from TCGA data: FGF5, CXCL5, IGFL2, MMP1, ADAM32, ADAM18, IGFL1, FGF8, FGF17, FGF19, FGF4, and FGF23.
Affiliation: Department of Hepatobiliary Surgery, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, China, lijian5@mail.sysu.edu.cn; zhangbm@mail.sysu.edu.cn. Department of Clinical Laboratory, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China. .
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2: Title: Highly heterogeneous genomic landscape of uterine leiomyomas by whole exome sequencing and genome-wide arrays.
Authors: Yatsenko, Svetlana A, et.al. .
Journal: Fertility and sterility (Fertil Steril), Vol. 107 (2): 457-466.e9, 2017 .
Snippet: We also identified mutations in a number of genes that were implicated in leiomyomagenesis such as COL4A6, DCN, and AHR, as well as novel genes: NRG1, ADAM18, HUWE1, FBXW4, FBXL13, and CAPRIN1.
Affiliation: Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Pathology, Magee-Women's Hospital of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania. Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Magee-Women's Research Institute, Pittsburgh, Pennsylvania; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee. Department of Pathology, Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, Pennsylvania. Department of Pathology, Magee-Women's Hospital of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania. Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Pathology, Magee-Women's Hospital of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Magee-Women's Research Institute, Pittsburgh, Pennsylvania. Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania; Magee-Women's Research Institute, Pittsburgh, Pennsylvania. Department of Gynecologic Oncology and Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Pathology, Magee-Women's Hospital of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Magee-Women's Research Institute, Pittsburgh, Pennsylvania. Electronic address: rajkovic@upmc.edu. .
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3: Title: The Rhesus macaque (Macaca mulatta) sperm proteome.
Authors: Skerget, Sheri, et.al. .
Journal: Molecular & cellular proteomics : MCP (Mol Cell Proteomics), Vol. 12 (11): 3052-67, 2013 .
Snippet: Phylogenetic and genomic analyses of three MacSP ADAMs (A-Disintegrin and Metalloprotease proteins), ADAM18-, 20- and 21-like, provides empirical support for sperm genes functioning in non-human primate taxa which have been subsequently lost in the lineages leading to humans.
Affiliation: Center for Infectious Diseases and Vaccinology, The Biodesign Institute, Arizona State University, Tempe, Arizona; .
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4: Title: Fetal growth restriction caused by MIMT1 deletion alters brain transcriptome in cattle.
Authors: Venhoranta, Heli, et.al. .
Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience (Int J Food Microbiol), Vol. 31 (7): 463-7, 2013 .
Snippet: Gene expression microarray analyses identified increased expression of VIPR2, HTRA1, S100A4 and MYH8 in fetuses carrying the deletion and decreased expression of DRD2, ADAM18, miR345, ZNF585A.
Affiliation: Department of Production Animal Medicine, University of Helsinki, Saarentaus, Finland. .
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5: Title: Positive selection at reproductive ADAM genes with potential intercellular binding activity.
Authors: Glassey, Barb, et.al. .
Journal: Molecular biology and evolution (Mol Biol Evol), Vol. 21 (5): 851-9, 2004 .
Snippet: We have examined the molecular evolution of the ADAM (a disintegrin and metalloprotease) gene family, a structurally and functionally diverse group of genes expressed in reproductive and somatic tissue to test whether a variety of protein characteristics such as phylogenetic clusters, tissue of expression, and proteolytic and adhesive function can group fast evolving ADAM genes.
Affiliation: Department of Biology, University of Winnipeg, Winnipeg, Manitoba, Canada. .
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6: Title: Human tMDC III: a sperm protein with a potential role in oocyte recognition.
Authors: Frayne, Jan, et.al. .
Journal: Molecular human reproduction (Mol Hum Reprod), Vol. 8 (9): 817-22, 2002 .
Snippet: Using a PCR-based approach, we have determined the complete nucleotide sequence of human tMDC III cDNA which, unlike the three non-functional genes, contains an uninterrupted open reading frame encoding a full-length MDC protein.
Affiliation: Department of Biochemistry, University of Bristol, School of Medical Sciences, University Walk, Bristol, BS8 1TD, UK. .
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7: Title: Identification of four novel ADAMs with potential roles in spermatogenesis and fertilization.
Authors: Zhu, G Z, et.al. .
Journal: Gene, Vol. 234 (2): 227-37, 1999 .
Snippet: The ADAM (A Disintegrin And Metalloprotease) family is known to have important roles in various developmental systems, e.g., myogenesis and neurogenesis.
Affiliation: Department of Cell Biology and Human Anatomy, School of Medicine, University of California Davis, Davis, CA 95616, USA. gzhu@ucdavis.edu .
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8: Title: Macaque MDC family of proteins: sequence analysis, tissue distribution and processing in the male reproductive tract.
Authors: Frayne, J, et.al. .
Journal: Molecular human reproduction (Mol Hum Reprod), Vol. 4 (5): 429-37, 1998 .
Snippet: Previous studies in the macaque (Macaca fascicularis) have led to the cDNA cloning and sequence analysis of a number of MDC proteins which are abundantly expressed in the male reproductive tract.
Affiliation: Department of Biochemistry, University of Bristol, School of Medical Sciences, UK. .
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9: Title: Rat MDC family of proteins: sequence analysis, tissue distribution, and expression in prepubertal and adult rat testis.
Authors: Frayne, J, et.al. .
Journal: Molecular reproduction and development (Mol Reprod Dev), Vol. 48 (2): 159-67, 1997 .
Snippet: Here, we report the cloning and sequence analysis of cDNAs encoding several rat orthologues of this protein family, some of which are found to be expressed exclusively in the male reproductive tract, others exhibiting a broader tissue distribution.
Affiliation: Department of Biochemistry, University of Bristol, School of Medical Sciences, UK. .
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