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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

SNF8, ESCRT-II complex subunit, homolog

Vps22, EAP30, SNF8, dot3
SNF8, VPS25 (MIM 610907), and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL; MIM 600284) (Slagsvold et al., 2005 [PubMed 15755741]; Kamura et al., 2001 [PubMed 11278625]).[supplied by OMIM, Mar 2008] (from NCBI)
Top mentioned proteins: Vps25, HAD, CAN, TSG101, VPS28
Papers on Vps22
Leaf hydraulic conductance varies with vein anatomy across Arabidopsis thaliana wild-type and leaf vein mutants.
Sack et al., Los Angeles, United States. In Plant Cell Environ, Dec 2015
We measured leaf hydraulic conductance (Kleaf ), vein traits, and xylem and mesophyll anatomy for A. thaliana WT (Col-0) and four vein mutants (dot3-111 and dot3-134, and cvp1-3 and cvp2-1).
Genetic basis for Saccharomyces cerevisiae biofilm in liquid medium.
Regenberg et al., Copenhagen, Denmark. In G3 (bethesda), 2014
Quantitative northern blots further revealed that AIM1, ASG1, AVT1, DRN1, ELP4, FLO8, FMP10, HMT1, KAR5, MIT1, MRPL32, MSS11, NCP1, NPR1, PEP5, PEX25, RIM8, RIM101, RGT1, SNF8, SPC2, STB6, STP22, TEC1, VID24, VPS20, VTC3, YBL029W, YBL029C-A, YFL054C, YGR161W-C, YIL014C-A, YIR024C, YKL151C, YNL200C, YOR034C-A, and YOR223W controlled biofilm through FLO11 induction.
Modulation of proteome expression by F-type lectin during viral hemorrhagic septicemia virus infection in fathead minnow cells.
Kim et al., Kwangju, South Korea. In Fish Shellfish Immunol, 2014
The expression of RbFTL-3 inhibits a vascular-sorting protein (SNF8) and diminishes the loss of prothrombin, which are closely associated with controlling viral budding and hemorrhage in fish cells, respectively.
Involvement of ESCRT-II in hepatitis B virus morphogenesis.
Prange et al., Mainz, Germany. In Plos One, 2013
In contrast, RNAi-mediated depletion of the ESCRT-II components EAP20, EAP30 and EAP45 greatly reduced virus egress.
Two novel type 2 diabetes loci revealed through integration of TCF7L2 DNA occupancy and SNP association data.
Grant et al., Philadelphia, United States. In Bmj Open Diabetes Res Care, 2013
When investigating all the known GWAS loci bound by TCF7L2 in the shortest gene list, derived from HCT116, the coronary artery disease-associated variant, rs46522 at the UBE2Z-GIP-ATP5G1-SNF8 locus, yielded significant association with T2D within DIAGRAM.
Identification of CAD candidate genes in GWAS loci and their expression in vascular cells.
Lusis et al., Los Angeles, United States. In J Lipid Res, 2013
By integrating human and mouse results, we predict that PPAP2B, GALNT4, MAPKAPK5, TCTN1, SRR, SNF8, and ICAM1 play a causal role in the susceptibility to atherosclerosis through a role in the vasculature.
Knockout of the VPS22 component of the ESCRT-II complex in rice (Oryza sativa L.) causes chalky endosperm and early seedling lethality.
Xie et al., Guangzhou, China. In Mol Biol Rep, 2013
In both yeast and mammals, the major constituent of the endosomal sorting complex required for transport-II (ESCRT-II) is the VPS22/EAP30 protein, which plays an important role in ubiquitin-mediated degradation of membrane proteins through the multivesicular body pathway.
De-regulation of JNK and JAK/STAT signaling in ESCRT-II mutant tissues cooperatively contributes to neoplastic tumorigenesis.
Bergmann et al., Houston, United States. In Plos One, 2012
Multiple genes involved in endocytosis and endosomal protein trafficking in Drosophila have been shown to function as neoplastic tumor suppressor genes (nTSGs), including Endosomal Sorting Complex Required for Transport-II (ESCRT-II) components vacuolar protein sorting 22 (vps22), vps25, and vps36.
ESCRT-II's involvement in HIV-1 genomic RNA trafficking and assembly.
Mouland et al., Montréal, Canada. In Biol Cell, 2012
We then depleted EAP30 (the orthologue for Vps22) by siRNA to target ESCRT-II in HIV-1 expressing cells.
SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity.
Schlöndorff et al., Boston, United States. In Bmc Cell Biol, 2011
RESULTS: Here we report that SNF8, a component of the endosomal sorting complex for transport-II (ESCRT-II) complex, interacts with TRPC6.
Multivesicular bodies mature from the trans-Golgi network/early endosome in Arabidopsis.
Schumacher et al., Heidelberg, Germany. In Plant Cell, 2011
The localization of the ESCRT components VPS28, VPS22, and VPS2 at the TGN/EE and MVBs/LEs indicates that the formation of intraluminal vesicles starts already at the TGN/EE.
Cargo-dependent degradation of ESCRT-I as a feedback mechanism to modulate endosomal sorting.
Stenmark et al., Oslo, Norway. In Traffic, 2011
We have investigated the endosomal localization of subunits of the four ESCRTs-Hrs (ESCRT-0), Tsg101 (ESCRT-I), EAP30/Vps22 (ESCRT-II) and charged multivesicular body protein 3/Vps24 (ESCRT-III).
Genome-wide mRNA and microRNA profiling of the NCI 60 cell-line screen and comparison of FdUMP[10] with fluorouracil, floxuridine, and topoisomerase 1 poisons.
Pommier et al., Winston-Salem, United States. In Mol Cancer Ther, 2010
Genes involved in endocytosis, such as clathrin (CLTC), SNF8, annexin A6 (ANXA6), and amyloid protein-binding 2 (APPBP2) uniquely correlated with sensitivity to FdUMP[10], consistent with a protein-mediated cellular uptake of FdUMP[10].
The interaction between EAP30 and ELL is modulated by MCM2.
Yankulov et al., Guelph, Canada. In Febs Lett, 2009
ELL-associated protein 30 (EAP30) was initially characterized as a component of the Holo-ELL complex, which contains the elongation factor ELL.
Vps22/EAP30 in ESCRT-II mediates endosomal sorting of growth factor and chemokine receptors destined for lysosomal degradation.
Stenmark et al., Oslo, Norway. In Traffic, 2007
Vps22 has an important role in ligand-induced EGFR and CXCR4 turnover; termination of EGF signaling occurs prior to ESCRT-II engagement
bicoid RNA localization requires specific binding of an endosomal sorting complex.
St Johnston et al., Cambridge, United Kingdom. In Nature, 2007
Here we show that mutants in all subunits of the ESCRT-II complex (VPS22, VPS25 and VPS36) abolish the final Staufen-dependent step in bicoid mRNA localization.
Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release.
Sundquist et al., Salt Lake City, United States. In J Virol, 2006
there are probably multiple pathways for protein sorting/multivesicular body vesicle formation in human cells and that human immunodeficiency virus type 1 does not utilize an ESCRT-II-dependent pathway to leave the cell
RILP interacts with the VPS22 component of the ESCRT-II complex.
Bucci et al., Lecce, Italy. In Biochem Biophys Res Commun, 2006
we have isolated EAP30/SNF8/VPS22 subunit of the ESCRT-II complex as a RILP interacting protein. We demonstrated that VPS22 interacts with the N-terminal half of RILP.
Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII.
Luzio et al., Cambridge, United Kingdom. In J Biol Chem, 2006
mammalian ESCRTII is made up of hVps25p, hVps22p, and hVps36p and may be redundant, cargo-specific, or not required for protein sorting at the multivesicular body
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