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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Secretoglobin, family 1A, member 1

Uteroglobin, Urinary protein, CC10, CC16, CCSP
This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma. [provided by RefSeq, May 2010] (from NCBI)
Top mentioned proteins: HAD, CAN, AGE, Serum albumin, ACID
Papers using Uteroglobin antibodies
User-guided 3D active contour segmentation of anatomical structures: significantly improved efficiency and reliability.
Ouchi Toru, In PLoS ONE, 2005
... The TetO-c-MYC and CCSP-rtTa transgenic lines generated for these ...
Effective polyethylenimine-mediated gene transfer into human endothelial cells
Cho Myung-Haing et al., In Journal of Veterinary Science, 2003
... Anti-CC10 antibody was obtained from Abcam (USA) ...
Early Growth Response Gene 1–mediated Apoptosis Is Essential for Transforming Growth Factor β1–induced Pulmonary Fibrosis
Elias Jack A. et al., In The Journal of Experimental Medicine, 2001
... Generation of the CC10-rtTA-tTS-TGF-β1 Mice.In virtually all inducible overexpression transgenic systems, there is a low ...
Interleukin-9 is involved in host protective immunity to intestinal nematode infection
Flavell Richard A. et al., In The Journal of Experimental Medicine, 1996
... After digestion of the plasmid with XhoI and SacII, the CC10-IL9-SV40 transgene was separated by electrophoresis through a 1% agarose gel (SeaKem GTG BioProducts, FMC; Rockland, ME), isolated by electroelution, ...
Papers on Uteroglobin
Dietary intake in Japanese patients with kidney transplantation.
Kanno et al., Tokyo, Japan. In Clin Exp Nephrol, Feb 2016
Urinary protein was shown in 30 % of patients.
Club Cell Protein 16 (CC16) Augmentation: A Potential Disease-modifying Approach for Chronic Obstructive Pulmonary Disease (COPD).
Owen et al., Boston, United States. In Expert Opin Ther Targets, Feb 2016
INTRODUCTION: Club cell protein 16 (CC16) is the most abundant protein in bronchoalveolar lavage fluid.
Intraoperative cell salvage during cardiac surgery is associated with reduced postoperative lung injury.
de Vries et al., Utrecht, Netherlands. In Interact Cardiovasc Thorac Surg, Jan 2016
METHODS: Serial measurements of systemic plasma concentrations of interleukin-6 (IL-6), myeloperoxidase, elastase, surfactant protein D (SP-D), Clara cell 16 kD protein (CC16) and soluble receptor for advanced glycation endproducts (sRAGEs) were performed on blood samples from 195 patients who underwent cardiac surgery with the use of a cell salvage (CS) device (CS, n = 99) or without (CONTROL, n = 96).
C22-bronchial and T7-alveolar epithelial cell lines of the immortomouse are excellent murine cell culture model systems to study pulmonary peroxisome biology and metabolism.
Baumgart-Vogt et al., Gießen, Germany. In Histochem Cell Biol, Jan 2016
UNASSIGNED: In pulmonary research, temperature-sensitive immortalized cell lines derived from the lung of the "immortomouse" (H-2k(b)-tsA58 transgenic mouse), such as C22 club cells and T7 alveolar epithelial cells type II (AECII), are frequently used cell culture models to study CC10 metabolism and surfactant synthesis.
Detecting Germline PTEN Mutations Among At-Risk Patients With Cancer: An Age- and Sex-Specific Cost-Effectiveness Analysis.
Eng et al., Singapore, Singapore. In J Clin Oncol, Sep 2015
At base-case, CC10 is the most cost-effective strategy for female patients who are younger than 40 years, and CC15 is the most cost-effective strategy for female patients who are between 40 and 60 years of age and male patients of all ages.
Urinary protein-to-creatinine ratio in pregnant women after dipstick testing: prospective observational study.
Minakami et al., Japan. In Bmc Pregnancy Childbirth, 2014
This study was performed to determine which pregnant women should be recommended to undergo determination of urinary protein-to-creatinine ratio (mg/mg, P/Cr test) after dipstick test for confirmation of SPIP.
Application of urine proteomics for biomarker discovery in drug-induced liver injury.
Russel et al., Nijmegen, Netherlands. In Crit Rev Toxicol, 2014
Urinary protein biomarker candidates for DILI have emerged in the past few years and correlate well with clinical studies for serum DILI biomarkers.
Early biomarkers as predictors for bronchopulmonary dysplasia in preterm infants: a systematic review.
Lu et al., Hangzhou, China. In Eur J Pediatr, 2014
Based on the nine highest quality studies, serum KL-6, CC16, neutrophil gelatinase-associated lipocalin, and end-tidal carbon monoxide (etCO) perform extremely well in predicting the early diagnosis of established BPD, highlighting these biomarkers as promising candidates for future research.
Association between CC10 +38A/G polymorphism and asthma risk: A meta-analysis.
Zhao et al., Guangzhou, China. In Pak J Med Sci, 2013
OBJECTIVES: A number of studies conducted to assess the association between Clara cell 10-kDa protein (CC10) +38A/G polymorphism and susceptibility to asthma have yielded inconsistent and inconclusive results.
Clara cell 10-kD protein in inflammatory upper airway diseases.
Liu et al., Wuhan, China. In Curr Opin Allergy Clin Immunol, 2013
PURPOSE OF REVIEW: To discuss the role of Clara cell 10-kD protein (CC10), an anti-inflammatory and immunomodulatory molecule, in inflammatory upper airway diseases, particularly in allergic rhinitis and chronic rhinosinusitis (CRS).
Evaluation of a common variant of the gene encoding clara cell 10 kd protein (CC10) as a candidate determinant for asthma severity and steroid responsiveness among Chinese children.
Huang et al., Taiwan. In J Asthma, 2012
CC10 G+38A variant may contribute to the severity of asthma and lower level of steroid responsiveness.
Long-term renal function, complications and life expectancy in living kidney donors.
Okamoto, Chiryū, Japan. In World J Transplant, 2012
Urinary protein showed small increases in this population and was associated with hypertension and a lower glomerular filtration rate.
Clara cell protein 10 polymorphism is not associated with severe respiratory syncytial virus infection.
Navér et al., Stockholm, Sweden. In Acta Paediatr, 2012
Single-nucleotide polymorphism in the CC10 gene (A38G) does not seem to be involved in the severity of respiratory syncytial virus infection or wheezing.
Early postnatal surge of serum Clara cell secretory protein in newborn infants.
Lui et al., Australia. In Neonatology, 2011
Serum Clara cell secretory protein levels were characterized by an early postnatal surge. This apparent gestation-influenced surge may represent an initiation of a protective cascade against postnatal lung injury during extrauterine adaptation.
Clara cell 10-kDa protein gene transfection inhibits NF-κB activity in airway epithelial cells.
Liu et al., Wuhan, China. In Plos One, 2011
These results indicate that CC10 gene transfer may inhibit airway inflammation through suppressing the activation of NF-kappaB.
Clara cell protein expression in human neonates during respiratory distress syndrome.
Irles et al., Mexico. In Cell Physiol Biochem, 2011
demonstration that cc-10 is differentially expressed in infants with iRDS may point the way towards one possible mechanism that potentially involves modifications of the protein structure with its anti-inflammatory and surfactant protective function
Uteroglobin: a steroid-inducible immunomodulatory protein that founded the Secretoglobin superfamily.
Chilton et al., Bethesda, United States. In Endocr Rev, 2007
Blastokinin or uteroglobin (UG) is a steroid-inducible, evolutionarily conserved, secreted protein that has been extensively studied from the standpoint of its structure and molecular biology.
Uteroglobin is essential in preventing immunoglobulin A nephropathy in mice.
Mukherjee et al., Bethesda, United States. In Nat Med, 1999
We report here that two independent mouse models (gene knockout and antisense transgenic), both manifesting deficiency of an anti-inflammatory protein, uteroglobin (UG), develop almost all of the pathologic features of human IgA nephropathy.
Uteroglobin: structure, molecular biology, and new perspectives on its function as a phospholipase A2 inhibitor.
Mukherjee et al., Bethesda, United States. In Endocr Rev, 1987
UG or blastokinin is a low molecular weight protein which is secreted by the endometrium of the rabbit during early pregnancy.
Effect of captopril on heavy proteinuria in azotemic diabetics.
Sasaki et al., In N Engl J Med, 1986
Urinary protein decreased promptly within two weeks (from 10.6 +/- 2.2 to 6.1 +/- 1.4 g per day [mean +/- S.E.M.]; P less than 0.01).
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