gopubmed logo
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Ubiquitin specific peptidase 48

USP48, ubiquitin specific protease 31, USP31
This gene encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: Ubiquitin, p65, OGT, CAN, Ku80
Papers on USP48
New Salting Out Stability-Indicating and Kinetic Thin Layer Chromatographic Method for Determination of Glimepiride and Metformin HCl Binary Mixture.
Ahmed et al., Asyūţ, Egypt. In J Chromatogr Sci, Oct 2015
The proposed method was validated according to ICH guidelines and complied with USP31-NF26 validation guidelines.
Immunohistochemical detection of FLAG-tagged endogenous proteins in knock-in mice.
French et al., San Francisco, United States. In J Histochem Cytochem, Apr 2015
Focusing on two 3 × FLAG-tagged proteins for which specific antibodies were available, USP48 and RIPK3, we were able to validate our anti-DDDDK assay by comparing the IHC directed against the actual proteins to the anti-DDDDK IHC assay, which recognizes the FLAG epitope.
CSN-associated USP48 confers stability to nuclear NF-κB/RelA by trimming K48-linked Ub-chains.
Naumann et al., Magdeburg, Germany. In Biochim Biophys Acta, Feb 2015
In this study we observed that USP48, a DUB of hitherto ill-defined function identified through a siRNA screen, associates with the CSN and RelA in the nucleus.
Dopamine D3 receptor inhibits the ubiquitin-specific peptidase 48 to promote NHE3 degradation.
Jose et al., Baltimore, United States. In Faseb J, 2014
We now offer and describe a novel mechanism by which D3R decreases sodium transport in the long term by inhibiting the deubiquitinylating activity of ubiquitin-specific peptidase 48 (USP48), thereby promoting Na(+)-H(+) exchanger (NHE)-3 degradation.
Variation in genes related to cochlear biology is strongly associated with adult-onset deafness in border collies.
Neff et al., San Francisco, United States. In Plos Genet, 2012
Through additional validation based on targeted genotyping of additional cases (n = 23 total) and controls (n = 101 total) and an independent replication cohort of 16 cases and 265 controls, we identified variants in USP31 that were strongly associated with adult-onset deafness in Border Collies, suggesting the involvement of the NF-κB pathway.
A novel injection-molded capsular device for oral pulsatile delivery based on swellable/erodible polymers.
Zema et al., Milano, Italy. In Aaps Pharmscitech, 2011
The performance of capsular devices filled with a tracer drug powder was studied by means of a modified USP31 disintegration apparatus.
Mononuclear cell transcriptome response after sustained virgin olive oil consumption in humans: an exploratory nutrigenomics study.
de la Torre et al., Barcelona, Spain. In Omics, 2009
The response to VOO consumption was confirmed for individual samples (n = 10) by qPCR for 10 upregulated genes (ADAM17, ALDH1A1, BIRC1, ERCC5, LIAS, OGT, PPARBP, TNFSF10, USP48, and XRCC5).
Characterization of human gene expression changes after olive oil ingestion: an exploratory approach.
Covas et al., Barcelona, Spain. In Folia Biol (praha), 2008
USP48 by 2.16; OGT by 1.68-fold change) and associated processes such as inflammation (e.g.
Human ubiquitin specific protease 31 is a deubiquitinating enzyme implicated in activation of nuclear factor-kappaB.
Hatzivassiliou et al., Thessaloníki, Greece. In Cell Signal, 2006
A yeast two-hybrid screen of a human cDNA library identified a ubiquitin specific protease homologue (USP31) as a TRAF2-interacting protein.
Identification of the human ubiquitin specific protease 31 (USP31) gene: structure, sequence and expression analysis.
Farrer et al., Jacksonville, United States. In Dna Seq, 2004
Here we report the identification and characterization of a novel human deubiquitylating gene (USP31), which maps to the critical PARK6 region.
share on facebooktweetadd +1mail to friends