gopubmed logo
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Solute carrier family 35, member D2

UDP-N-acetylglucosamine transporter, HFRC1, SLC35D2, HFRC
Nucleotide sugars, which are synthesized in the cytosol or the nucleus, are high-energy donor substrates for glycosyltransferases located in the lumen of the endoplasmic reticulum and Golgi apparatus. Translocation of nucleotide sugars from the cytosol into the lumen compartment is mediated by specific nucleotide sugar transporters, such as SLC35D2 (Suda et al., 2004 [PubMed 15082721]).[supplied by OMIM, Mar 2008] (from NCBI)
Top mentioned proteins: ACID, SLC35A3, UGT, Cho, HAD
Papers on UDP-N-acetylglucosamine transporter
UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats).
Olczak et al., Wrocław, Poland. In J Biol Chem, Jul 2015
UDP-galactose transporter (UGT; SLC35A2) and UDP-N-acetylglucosamine transporter (NGT; SLC35A3) form heterologous complexes in the Golgi membrane.
Identification of a Golgi-localized UDP-N-acetylglucosamine transporter in Trypanosoma cruzi.
Ramos et al., São Paulo, Brazil. In Bmc Microbiol, 2014
A UDP-N-acetylglucosamine transporter, TcNST1, was identified by a yeast complementation approach.
Short N-terminal region of UDP-galactose transporter (SLC35A2) is crucial for galactosylation of N-glycans.
Olczak et al., Wrocław, Poland. In Biochem Biophys Res Commun, 2014
UDP-galactose transporter (UGT) and UDP-N-acetylglucosamine transporter (NGT) form heterologous complexes in the Golgi apparatus (GA) membrane.
UDP-N-acetylglucosamine transporter (SLC35A3) regulates biosynthesis of highly branched N-glycans and keratan sulfate.
Olczak et al., Wrocław, Poland. In J Biol Chem, 2013
SLC35A3 is considered the main UDP-N-acetylglucosamine transporter (NGT) in mammals.
UDP-Gal/UDP-GlcNAc chimeric transporter complements mutation defect in mammalian cells deficient in UDP-Gal transporter.
Olczak et al., Wrocław, Poland. In Biochem Biophys Res Commun, 2013
The role of UDP-galactose transporter (UGT; SLC35A2) and UDP-N-acetylglucosamine transporter (NGT; SLC35A3) in glycosylation of macromolecules may be coupled and either of the transporters may partially replace the function played by its partner.
Prognostic implications of genetic variants in advanced non-small cell lung cancer: a genome-wide association study.
Lee et al., South Korea. In Carcinogenesis, 2013
These SNPs were located in the genomic regions of the FAM154A, ANKS1A, DLST, THSD7B, NCOA2, CDH8, SLC35D2, NALCN and EGF genes.
UDP-N-acetylglucosamine transporter and UDP-galactose transporter form heterologous complexes in the Golgi membrane.
Olczak et al., Wrocław, Poland. In Febs Lett, 2012
UDP-galactose transporter (UGT; SLC35A2) and UDP-N-acetylglucosamine transporter (NGT; SLC35A3) are evolutionarily related.
Differential expression of select members of the SLC family of genes and regulation of expression by microRNAs in the chicken oviduct.
Bazer et al., Seoul, South Korea. In Biol Reprod, 2012
Expression of SLC1A4 (glutamate and neutral amino acid transporter), SLC13A2 (dicarboxylate transporter), and SLC35B4 (UDP-xylose: UDP-N-acetylglucosamine transporter) mRNAs was limited to glandular epithelium (GE), while SLC4A5 (sodium bicarbonate cotransporter) and SLC7A3 (cationic amino acid transporter) mRNAs were expressed predominantly in the luminal epithelium of the magnum.
Functional analysis of a Hansenula polymorpha MNN2-2 homologue encoding a putative UDP-N-acetylglucosamine transporter localized in the endoplasmic reticulum.
Kang et al., Seoul, South Korea. In J Microbiol, 2011
The Kluyveromyces lactis UDP-GlcNAc transporter (KlMnn2-2p) is responsible for the biosynthesis of N-glycans containing N-acetylglucosamine.
Endoplasmic reticulum/golgi nucleotide sugar transporters contribute to the cellular release of UDP-sugar signaling molecules.
Lazarowski et al., Chapel Hill, United States. In J Biol Chem, 2009
HFRC1 was overexpressed in human bronchial epithelial cells and was shown to localize in the Golgi and to enhance the surface expression of N-acetylglucosamine-rich glycans.
Tissue-specific mRNA expression profiles of human solute carrier 35 transporters.
Naito et al., Tokushima, Japan. In Drug Metab Pharmacokinet, 2008
The mRNA expression of SLC35As, SLC35Bs, SLC35Cs, SLC35D1, SLC35D2, SLC35Es, and SLC35F5 was found to be ubiquitous in both adult and fetal tissues.
[The development and application of method for detecting bovine complex vertebral malformation].
Zhong et al., China. In Yi Chuan, 2008
The molecular cause of CVM was a substitution of guanine by thymine (G-->T) in a solute carrier family 35 member 3 gene (SLC35A3), encoding UDP-N-acetylglucosamine transporter.
Isolation, sequence identification and tissue expression distribution of three novel porcine genes--RAB14, S35A3 and ITM2A.
Gao et al., Kunming, China. In Mol Biol Rep, 2008
The porcine S35A3 gene encodes a protein of 325 amino acids that contains the conserved putative nucleotide-sugar transporter domain and has high homology with the UDP-N-acetylglucosamine transporter (S35A3) of five species--cattle (98%), dog (97%), human (96%), mouse (95%) and rat (94%).
The impact of patient-specific quality-of-care report cards on guideline adherence in heart failure.
Koelling et al., Ann Arbor, United States. In Am Heart J, 2007
BACKGROUND: It is unknown if physician education through heart failure (HF) patient-specific quality-of-care report cards (HFRC) impacts outpatient HF guideline adherence.
Gene expression profiling, chromosome assignment and mutational analysis of the porcine Golgi-resident UDP-N-acetylglucosamine transporter SLC35A3.
Thomsen et al., Århus, Denmark. In Mol Membr Biol, 2007
SLC35A3 encodes a Golgi-resident UDP-N-acetylglucosamine transporter.
Molecular cloning and characterization of a human multisubstrate specific nucleotide-sugar transporter homologous to Drosophila fringe connection.
Nishihara et al., Hachiōji, Japan. In J Biol Chem, 2004
HFRC1 takes part in the synthesis of heparan sulfate by regulating the level of UDP-GlcNAc, a donor substrate for the heparan sulfate synthases
share on facebooktweetadd +1mail to friends