Twinfilin-2a is dispensable for mouse development.
Helsinki, Finland. In Plos One, 2010
These data suggest that twinfilin-2a plays a redundant role in cytoskeletal dynamics with the biochemically similar twinfilin-1, which is typically co-expressed in same tissues with twinfilin-2a.
Twinfilin 2 regulates actin filament lengths in cochlear stereocilia.
Stanford, United States. In J Neurosci, 2010
This study suggested that twinfilin 2 plays a role in the regulation of stereocilia elongation by restricting excessive elongation of the shorter row stereocilia thereby maintaining the mature staircase architecture of cochlear hair bundles.
Inhibition of monkeypox virus replication by RNA interference.
United States. In Virol J, 2008
Seven siRNA constructs from these two pools, targeting either an essential gene for viral replication (A6R) or an important gene in viral entry (E8L), inhibited viral replication in cell culture by 65-95% with no apparent cytotoxicity.