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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Cell adhesion molecule 4

TSLL2, IGSF4C, cell adhesion molecule 4, SynCAM4, Necl4
Top mentioned proteins: cell adhesion molecule-1, Nectin-4, nectin-1, CD45, HAD
Papers on TSLL2
Involvement of membrane skeletal molecules in the Schmidt-Lanterman incisure in Schwann cells.
Ohno et al., Matsumoto, Japan. In Med Mol Morphol, Dec 2015
An analogous molecular complex, 4.1G-MPP6-cell adhesion molecule 4 (CADM4), is incorporated into the Schmidt-Lanterman incisure (SLI), a truncated cone shape in the myelin internode that is a specific feature of myelinated nerve fibers formed in Schwann cells in the peripheral nervous system.
Cadm4 restricts the production of cardiac outflow tract progenitor cells.
Yelon et al., San Diego, United States. In Cell Rep, 2014
Here, we find that cell adhesion molecule 4 (cadm4) is essential for restricting the size of the zebrafish OFT.
Carcinoembryonic antigen-related cell adhesion molecule 4 (CEACAM4) is specifically expressed in medullary thyroid carcinoma cells.
Mochizuki et al., Shizuoka, Japan. In Biomed Res, 2013
Carcinoembryonic antigen (CEA), an oncofetal cell surface glycoprotein, has been widely used as a human tumor marker due to its high expression in tumors and secretion to serum.
Genetic deletion of Cadm4 results in myelin abnormalities resembling Charcot-Marie-Tooth neuropathy.
Peles et al., Israel. In J Neurosci, 2013
This family consists of four members: Cadm4/Necl4 and Cadm1/Necl2 are found in both glia and axons, whereas Cadm2/Necl3 and Cadm3/Necl1 are expressed by sensory and motor neurons.
An essential role of MAG in mediating axon-myelin attachment in Charcot-Marie-Tooth 1A disease.
Schaeren-Wiemers et al., Basel, Switzerland. In Neurobiol Dis, 2013
In this study, we examined the expression of MAG and Necl4, two critical adhesion molecules that are present at the axon-glia interface, in sural nerve biopsies of CMT1A patients and in peripheral nerves of mice overexpressing human PMP22, an animal model for CMT1A.
Necl-4/SynCAM-4 is expressed in myelinating oligodendrocytes but not required for axonal myelination.
Qiu et al., Louisville, United States. In Plos One, 2012
We generated Necl4 gene knockout mice, but found that disruption of Necl-4 gene did not affect oligodendrocyte differentiation and myelin formation in the CNS.
Aberrations of a cell adhesion molecule CADM4 in renal clear cell carcinoma.
Murakami et al., Tokyo, Japan. In Int J Cancer, 2012
CADM4, as well as 4.1B is expressed specifically in human proximal tubules.
Clinical significance of hypermethylation status in NSCLC: evaluation of a 30-gene panel in patients with advanced disease.
Minarik et al., Plzeƈ, Czech Republic. In Anticancer Res, 2011
Most frequently methylated were cadherin-13 (CDH13), Ras associated domain-containing protein (RASSF1A), Wilms' tumor protein (WT1), adenomatous polyposis coli protein (APC), paired box protein Pax-5 (PAX5), estrogen receptor (ESR1), an inhibitor of cyclin-dependent kinase p15 (CDKN2B), paired box protein Pax-6 (PAX6), transcription factor GATA-5 (GATA5) and cell adhesion molecule 4 (IGSF4).
Lack of protein 4.1G causes altered expression and localization of the cell adhesion molecule nectin-like 4 in testis and can cause male infertility.
An et al., New York City, United States. In Mol Cell Biol, 2011
findings imply that 4.1G plays a role in spermatogenesis by mediating cell-cell adhesion between spermatogenic and Sertoli cells through its interaction with NECL4 on Sertoli cells
Schwann cell spectrins modulate peripheral nerve myelination.
Rasband et al., Houston, United States. In Proc Natl Acad Sci U S A, 2011
Finally, we demonstrate that loss of spectrin significantly reduces both F-actin in the Schwann cell cytoskeleton and the Nectin-like protein, Necl4, at the contact site between Schwann cells and axons.
[Nectin and nectin-like molecules as markers, actors and targets in cancer].
Lopez et al., France. In Med Sci (paris), 2010
On the opposite, necl-1, necl-2 and necl-4 act as tumor suppressors and are repressed in cancer.
The cell adhesion nectin-like molecules (Necl) 1 and 4 suppress the growth and tumorigenic ability of colon cancer cells.
Ben-Ze'ev et al., Israel. In J Cell Biochem, 2009
Nec- 4 suppress the growth and tumorigenic ability of colon cancer cells.
Altered expression of nectin-like adhesion molecules in the peripheral nerve after sciatic nerve transection.
Cullheim et al., Stockholm, Sweden. In Neurosci Lett, 2009
The signals for necl-4 and necl-5 mRNA both increased in the injured nerve and necl immunoreactivity displayed a close relation to axon and Schwann cell markers.
A central role for Necl4 (SynCAM4) in Schwann cell-axon interaction and myelination.
Peles et al., Israel. In Nat Neurosci, 2007
Necl4 is the main Necl expressed by myelinating Schwann cells and is located along the internodes in direct apposition to Necl1, which is localized on axons.
Cell adhesion and prostate tumor-suppressor activity of TSLL2/IGSF4C, an immunoglobulin superfamily molecule homologous to TSLC1/IGSF4.
Murakami et al., Tokyo, Japan. In Oncogene, 2006
TSLL2 is expressed at the cell-cell attachment sites in the renal tubules, the transitional epithelia of the bladder, and the glandular epithelia of the prostate, and is a tumor-suppressor candidate in prostate cancer.
Subchronic exposure to TCDD, PeCDF, PCB126, and PCB153: effect on hepatic gene expression.
Olson et al., Madison, United States. In Environ Health Perspect, 2004
Many genes were co-expressed during the 13-week TCDD, PeCDF, or PCB126 exposures, including classical AhR-regulated genes and some genes not previously characterized as being AhR regulated, such as carcinoembryonic-cell adhesion molecule 4 (C-CAM4) and adenylate cyclase-associated protein 2 (CAP2).
Identification and characterization of human TMEM25 and mouse Tmem25 genes in silico.
Katoh et al., Narashino, Japan. In Oncol Rep, 2004
IGSF4 (IGSF4A), homologous to IGSF4B, IGSF4C, IGSF4D, PVR, PVRL1, PVRL2, PVRL3 and PVRL4, is down-regulated in lung cancer.
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