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Teashirt zinc finger family member 3

TSHZ3, Teashirt 3, Tsh3
Top mentioned proteins: Teashirt, CAN, OUT, Myocardin, Histone
Papers on TSHZ3
Altered epigenetic regulation of homeobox genes in human oral squamous cell carcinoma cells.
Gudas et al., New York City, United States. In Exp Cell Res, 2014
In contrast, IRX1, IRX4, SIX2 and TSHZ3 transcripts are lower in SCC-9 than in OKF6-TERT1R cells.
Whole-genome sequencing of the world's oldest people.
Kim et al., Los Angeles, United States. In Plos One, 2013
We followed up on the gene most enriched for rare protein-altering variants in our cohort of supercentenarians, TSHZ3, by sequencing it in a second cohort of 99 long-lived individuals but did not find a significant enrichment.
A novel OPA3 mutation revealed by exome sequencing: an example of reverse phenotyping.
Lohmann et al., Lübeck, Germany. In Jama Neurol, 2013
Exome sequencing revealed 2 rare, homozygous variants (c.32 T>A [p.L11Q] in OPA3 and c.941 C>G [p.A314G] in TSHZ3) that segregated with the disease.
TSHZ3 and SOX9 regulate the timing of smooth muscle cell differentiation in the ureter by reducing myocardin activity.
Fasano et al., Marseille, France. In Plos One, 2012
In the mouse ureter, the two transcriptional regulators TSHZ3 and SOX9 are independently required for initiation of smooth muscle differentiation from uncommitted mesenchymal precursor cells.
Should functional sensitivity of a new thyroid stimulating hormone immunoassay be monitored routinely? The ADVIA Centaur TSH3-UL assay experience.
Agin et al., Strasbourg, France. In Clin Biochem, 2012
OBJECTIVES: We emphasize the importance of routine follow-up of subnormal TSH concentrations with QC materials.
Tandem duplication of chromosomal segments is common in ovarian and breast cancer genomes.
Bowtell et al., Cambridge, United Kingdom. In J Pathol, 2012
Recurrent rearrangements of the transcriptional regulator gene, TSHZ3, were found in three of eight serous cases.
Teashirt-3, a novel regulator of muscle differentiation, associates with BRG1-associated factor 57 (BAF57) to inhibit myogenin gene expression.
Fasano et al., Marseille, France. In J Biol Chem, 2011
suggest a novel mechanism for transcriptional repression by TSHZ3 in which TSHZ3 and BAF57 cooperate to modulate MyoD activity on the Myog promoter to regulate skeletal muscle differentiation.
Genetic loci for blood lipid levels identified by linkage and association analyses in Caribbean Hispanics.
Sacco et al., Miami, United States. In J Lipid Res, 2011
In the association analysis of the linkage peaks, we found that seven SNPs near FLJ45974 were associated with LDL-C/HDL-C with a nominal P < 3.5 × 10(-5), in addition to associations (P < 0.0001) for other lipid traits with SNPs in or near CDH13, SUMF2, TLE3, FAH, ARNT2, TSHZ3, ZNF343, RPL7AL2, and TMC3.
Rare and frequent promoter methylation, respectively, of TSHZ2 and 3 genes that are both downregulated in expression in breast and prostate cancers.
Yamamoto et al., Los Angeles, United States. In Plos One, 2010
TSHZ3 gene promoter was found to be methylated in all the breast/prostate cancer cell lines and some of the breast cancer clinical specimens while the TSHZ2 gene promoter was unmethylated except for the MDA-MB-231 breast cancer cell line.
Teashirt 3 regulates development of neurons involved in both respiratory rhythm and airflow control.
Fasano et al., Marseille, France. In J Neurosci, 2010
Thus, a single gene, Tshz3, controls the development of diverse components of the circuitry required for breathing.
Ureter myogenesis: putting Teashirt into context.
Woolf et al., London, United Kingdom. In J Am Soc Nephrol, 2010
Teashirt-3 (Tshz3) is expressed in smooth muscle cell precursors that form the wall of the forming mammalian ureter.
Analysis of TSHZ2 and TSHZ3 genes in congenital pelvi-ureteric junction obstruction.
Woolf et al., Oxford, United Kingdom. In Nephrol Dial Transplant, 2010
Mutations in TSHZ2 and TSHZ3 are not a major cause of pelvi-ureteric junction obstruction, at least in Albanian and Macedonian populations.
Latent physiological factors of complex human diseases revealed by independent component analysis of clinarrays.
Butte et al., Stanford, United States. In Bmc Bioinformatics, 2009
TSH3, a measure of thyroid function, and blood urea nitrogen, indicative of kidney function, were factors unique to type 1 diabetes respective to type 2 diabetes.
FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4.
Buxbaum et al., New York City, United States. In Plos One, 2008
We evaluated a case-control cohort and observed evidence for a genetic association between the Teashirt genes TSHZ1 and TSHZ3 and AD, with the TSHZ3 SNP genotype correlating with expression of Teashirt3.
Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4.
Fasano et al., Marseille, France. In Development, 2008
ureteric smooth muscle cell precursors express the transcription factor teashirt 3 (TSHZ3), and Tshz3-null mutants have congenital hydronephrosis without anatomical obstruction
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