GoPubMed Proteins lists recent and important papers and reviews for
proteins. Page last changed on 19 Dec 2016.
Tripartite motif containing 45
TRIM45
This gene encodes a member of the tripartite motif family. The encoded protein may function as a transcriptional repressor of the mitogen-activated protein kinase pathway. Alternatively spliced transcript variants have been described.[provided by RefSeq, Mar 2009] (from
NCBI)
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Top mentioned proteins:
Trim, AP-1, MAPK, NET, Ubiquitin
Papers on
TRIM45
The TRIM-FLMN protein TRIM45 directly interacts with RACK1 and negatively regulates PKC-mediated signaling pathway.
New
Sapporo, Japan. In Oncogene, Apr 2015
Here, we show that one of the tripartite motif-containing (TRIM) family ubiquitin ligases, TRIM45, is a novel RACK1-interacting protein and downregulates MAPK signal transduction.
Concurrent gene signatures for han chinese breast cancers.
Taipei, Taiwan. In Plos One, 2012
A breast cancer risk predictive model was built based on the first supervised principal component from 16 genes (RCAN3, MCOLN2, DENND2D, RWDD3, ZMYM6, CAPZA1, GPR18, WARS2, TRIM45, SCRN1, CSNK1E, HBXIP, CSDE1, MRPL20, IKZF1, and COL20A1), and distinct survival patterns were observed between the high- and low-risk groups from the combined dataset of 408 microarrays.
TRIM45 negatively regulates NF-κB-mediated transcription and suppresses cell proliferation.
GeneRIF
Sapporo, Japan. In Biochem Biophys Res Commun, 2012
These findings suggest that TRIM45 acts as a repressor for the NF-kappaB signal and regulates cell growth.
TRIM45, a novel human RBCC/TRIM protein, inhibits transcriptional activities of ElK-1 and AP-1.
GeneRIF
Changsha, China. In Biochem Biophys Res Commun, 2004
TRIM45 may act as a new transcriptional repressor in mitogen-activated protein kinase signaling pathway
