1.25 Å resolution structure of an RNA 20-mer that binds to the TREX2 complex.
Cambridge, United Kingdom. In Acta Crystallogr Sect F Struct Biol Commun, Oct 2015
The 1.25 Å resolution H32:R crystal structure of a 20 nt ribonucleotide that binds to the TREX-2 complex with high affinity shows a double-stranded RNA duplex arranged along a crystallographic 31 axis in which the antiparallel chains overlap by 18 nucleotides and are related by a crystallographic twofold axis.
mRNA export and gene expression: the SAGA-TREX-2 connection.
Valencia, Spain. In Biochim Biophys Acta, 2012
In this review, we focus on the functional coupling of gene transcription and mRNA export, and place particular emphasis on the relationship between the NPC-associated complex, TREX2, and the transcription co-activator, SAGA.